Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
Recruiting
Abbreviated Title: Neoadjuvant FOLFIRINOX combined with Pembrolizumab followed by surgery for patients with resectable pancreatic cancer Trial Phase: Phase II Clinical Indication: Pancreatic ductal adenocarcinoma; Adenocarcinoma; AJCC I, II, or III; 1st Line neoadjuvant Trial Type: Interventional prospective Type of control: Historical Route of administration: IV Treatment Groups: Neoadjuvant FOLFIRINOX combined with Pembrolizumab followed by surgery for patients with resectable pancreatic cance... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Pancreatic Ductal Adenocarcinoma
Hepatic Histopathology in Urea Cycle Disorders
Recruiting
This is a multi-site, retrospective chart review as well as a prospective study to evaluate histopathologic findings in liver samples from individuals with any UCD diagnosis. This study will be conducted at all Urea Cycle Disorders Consortium (UCDC) sites: Baylor College of Medicine in Houston, TX and Children's National Medical Center in Washington D.C.
Gender:
ALL
Ages:
All
Trial Updated:
07/17/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency, Citrullinemia 1, ARGI Deficiency, ASL Deficiency, Argininosuccinic Aciduria, ASS Deficiency, Hyperargininemia, Carbamyl Phosphate Synthetase Deficiency, NAGS Deficiency
Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas
Recruiting
This study involved patients that have a cancer called diffuse large B cell lymphoma (DLBCL), NK and T cell lymphomas (NK/TL) or classical Hodgkin lymphoma (cHL) (hereafter these 3 diseases will be referred to as lymphoma). Patients lymphoma has come back or not gone away after treatment. Because there is no standard treatment for the patients cancer at this time or because the currently used treatments do not work fully in all cases, the patients are being asked to volunteer in this research st... Read More
Gender:
ALL
Ages:
Between 12 years and 75 years
Trial Updated:
07/17/2025
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, Classical Hodgkin Lymphoma
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
Recruiting
Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing (PS) femoral component in complex primary total knee arthroplasty.
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
07/17/2025
Locations: Texas Institute for Hip & Knee Surgery, Austin, Texas
Conditions: Primary Knee Arthroplasty
Frame Support Study
Recruiting
This is a randomized, controlled pilot study evaluating an intervention of non-significant risk. Potential subjects will be women who have completed an initial new patient consultation at one of the participating fertility clinics. Approximately 400 subjects will be enrolled from multiple fertility clinics.
Gender:
FEMALE
Ages:
Between 22 years and 44 years
Trial Updated:
07/16/2025
Locations: Inception Fertility Research Institute, Houston, Texas
Conditions: Fertility Issues, Emotional Stress
A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis.
Recruiting
The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help to decrease nausea severity associated with idiopathic gastroparesis severity in adult subjects. The main questions it aims to answer are: * To evaluate the efficacy of CIN-102 on symptoms of gastroparesis when given to patients with idiopathic gastroparesis compared to a placebo * To evaluate the safety of CIN-102 when given to patients with idiopathic gastroparesis compared to a placebo Partic... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Digestive Health - UT Health Austin, Austin, Texas
Conditions: Idiopathic Gastroparesis
A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
Recruiting
This study will be conducted to evaluate INCB177054 given as monotherapy or in combination with retifanlimab in participants with select advanced or metastatic solid Tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: South Texas Accelerated Research Therapeutics, San Antonio, Texas
Conditions: Solid Tumors, Advanced Solid Tumors, Metastatic Solid Tumors
Fertilo In Vitro Research Study and Trial
Recruiting
The goal of this clinical trial is to evaluate the safety and efficacy of using Fertilo for In vitro maturation (IVM) in participants 18-35 years of age. The main question it aims to answer is whether the use of Fertilo is superior to using Medicult IVM for In vitro maturation. Researchers will compare the number of ongoing pregnancies at 12 weeks gestation for participants in each arm. * Arm 1 participants will have all cumulus oocyte complexes (COCs), or eggs surrounded by helper cells, cult... Read More
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
07/16/2025
Locations: Dallas Fort Worth Fertility Associates, Dallas, Texas
Conditions: In Vitro Maturation of Oocytes
Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients
Recruiting
The primary objective is to evaluate the efficacy of Ropanicant at two different dosage levels compared to placebo in patients with Major Depressive Disorder (MDD).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/16/2025
Locations: Community Clinical Research, Inc., Austin, Texas
Conditions: Major Depressive Disorder (MDD)
Paired Vagus Nerve Stimulation Mechanisms
Recruiting
In this mechanistic study, 40 individuals with chronic stroke will be implanted with a small vagus nerve stimulation (VNS) device. The study will use a randomized, blinded, crossover design to deliver two conditions in six-week blocks: active VNS or sham VNS, each paired with upper extremity (UE) motor rehabilitation. Assessment visits will occur before and after each block, and will examine neural pathway strength, functional connectivity, and motor and non-motor behaviors. Investigators will t... Read More
Gender:
ALL
Ages:
Between 22 years and 79 years
Trial Updated:
07/16/2025
Locations: The University of Texas at Dallas, Richardson, Texas
Conditions: Chronic Stroke
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1
Recruiting
This study will assess how effective, safe, and long-lasting a long-acting antiretroviral therapy (ART) using CAB LA + RPV LA is for people with HIV who still have detectable virus levels despite being on oral ART. The study will also consider feedback from patients on their experience with this treatment.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
07/16/2025
Locations: GSK Investigational Site, Dallas, Texas
Conditions: HIV Infections
Suvorexant for Treatment of AUD and PTSD
Recruiting
This study is to determine if suvorexant (SUV) will reduce insomnia in 76 men and women veteran and non-veterans between the ages 21-65 with posttraumatic stress disorder (PTSD) symptoms and alcohol use disorder (AUD). All participants will have a 7-day placebo run-in period, followed by a random assignment to receive placebo or suvorexant for an additonal 14 days. Post-randomization, participants will attempt to stop drinking for two weeks and will complete daily virtual diaries and study outco... Read More
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
07/16/2025
Locations: The University of Texas Health Science Center - Houston, Houston, Texas
Conditions: Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia