Texas is currently home to 4879 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Sacroiliac (SI) Joint Transfixing and Fusion: Meaningful Long Term Outcomes With Nevro1
Recruiting
The goal of this observational study is to learn if Nevro1 Sacroiliac Transfixing and Fusion System can treat sacroiliac joint dysfunction in males or females over 21. The main questions it aims to answer is what percentage of patients have clinically important pain relief with no adverse events, and what proportion of patients have fusion of the sacroiliac joint at 1 year and 2 years.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/02/2025
Locations: Advanced Spine and Pain Specialists, Spring, Texas
Conditions: Sacroiliac Joint Dysfunction
Evaluating Occupational Stress in Surgeons and Musicians: A Multi-modal Pilot Study Using Wearable EEG, Biomarker Analysis and Validated Questionnaires
Recruiting
To learn about occupational stress among surgeons and musicians by integrating psychological assessments, neurophysiological measures, and biomarkers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Occupational Stress
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function
Recruiting
The purpose of this study is to measure the effect of HI on the PK, safety, and tolerability of a single dose of mavorixafor compared to matched healthy volunteers (HVs) with normal hepatic function.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/02/2025
Locations: Texas Liver Institute/Alamo Medical Research, San Antonio, Texas
Conditions: Hepatic Insufficiency
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration
Recruiting
This is a Phase 1/Phase 2 multicenter study to evaluate the safety and efficacy of a one-time single-eye intravitreal dose of SAR402663 in participants with neovascular age-related macular degeneration. Participants will be enrolled in one of 2 parts: * In Part I (dose escalation), multiple dose levels of SAR402663 will be evaluated in successive cohorts of participants * In Part II (dose expansion), participants will be randomized to receive one of two dose levels selected based on data from... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
04/02/2025
Locations: Site # 8400015, Austin, Texas
Conditions: Neovascular Age-related Macular Degeneration
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Recruiting
A Phase 1, Open label, Multiple Ascending Dose Study to Assess Safety and Tolerability of STM-01 in Participants with Heart Failure with Preserved Ejection Fraction (HFpEF)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)
Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence
Recruiting
This is a multicentered, double-blind, randomized controlled, surgical trial of 358 women with inadequate symptom relief of stress urinary incontinence (SUI) or stress predominant mixed urinary incontinence (MUI) after conservative care. The Primary Aim is to determine the comparative effectiveness (as defined by "much" or "very much" better on PGI-I) of transurethral bulking agent (TBA) \[for 1 or 2 injections in 12 months\] vs. single-incision sling (SIS) 12 months after treatment interventio... Read More
Gender:
FEMALE
Ages:
21 years and above
Trial Updated:
04/02/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Stress Urinary Incontinence, Urinary Incontinence, Mixed Urinary Incontinence
A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis
Recruiting
The primary objective of this post-marketing study is to assess the safety and tolerability of apremilast in pediatric participants (ages 6 through 17 years) with mild to moderate plaque psoriasis.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
04/02/2025
Locations: Studies in Dermatology LLC, Cypress, Texas
Conditions: Plaque Psoriasis
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Recruiting
To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled corticosteroids (ICS) and at least one additional asthma controller medication with or without oral corticosteroids.
Gender:
ALL
Ages:
Between 5 years and 11 years
Trial Updated:
04/02/2025
Locations: Research Site, Coppell, Texas
Conditions: Asthma
A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors
Recruiting
To find the recommended dose of eribulin that can be given in combination with irinotecan and temozolomide to treat relapsed and/or refractory solid tumors.
Gender:
ALL
Ages:
Between 1 year and 25 years
Trial Updated:
04/02/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Refractory Solid Tumors
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
Recruiting
This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.
Gender:
ALL
Ages:
Between 21 years and 99 years
Trial Updated:
04/02/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Calcium Phosphate Kidney Stones
Abbott Ventricular Tachycardia PAS
Recruiting
This post-approval study (PAS) is designed to provide continued clinical evidence to confirm the long-term safety and effectiveness of the FlexAbilityTM Ablation Catheter, Sensor EnabledTM (FlexAbility SE) for the treatment of ventricular tachycardia in a post-market environment. This is a prospective, single arm, open-label, multi-center, observational study.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
04/02/2025
Locations: Baylor Scott & White Heart & Vascular Hospital, Dallas, Texas
Conditions: Ventricular Tachycardia
δ in Dementia Clinical Trials
Recruiting
The goal of this clinical trial is to demonstrate potential improvements in clinical trial methods relating to dementia and cognitive decline. The main questions it aims to answer are: * Can an intervention's outcome be better assessed by a latent variable ("δ") integrating cognitive performance with functional status? * Can latent biomarkers of δ guide the selection of an intervention that will modulate dementia severity? * Can a latent variable, derived from information collected remotely fro... Read More
Gender:
ALL
Ages:
Between 65 years and 100 years
Trial Updated:
04/02/2025
Locations: Univeristy of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, Texas
Conditions: Alzheimer's Disease (AD), Dementia, Cognitive Decline, Mild Cognitivie Impairment (MCI)