Texas is currently home to 4873 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Establishing Daily Applicable Parameters for Using Magnetic Resonance Spectroscopy of Spinal Cord
Recruiting
To learn if MRS can effectively assess spinal cord lesions.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Spinal Cord
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
Recruiting
The MATIC-2 is a multicenter clinical trial enrolling children who are less than 18 years of age with hemorrhagic shock potentially needing significant blood transfusion. The primary objective of the clinical trial is to determine the effectiveness of Low Titer Group O Whole Blood (LTOWB) compared to component therapy (CT), and Tranexamic Acid (TXA) compared to placebo in decreasing 24-hour all-cause mortality in children with traumatic life threatening hemorrhage.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
03/27/2025
Locations: The University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Hemorrhagic Shock, Trauma Injury
Approach-Avoidance and Alcohol Challenge Study in PTSD
Recruiting
Individuals with posttraumatic stress disorder (PTSD) have greater prevalence of alcohol use disorders (AUDs), with this comorbidity associated with worse illness outcomes, yet there remains limited mechanistic understanding of how PTSD confers risk for AUD. Understanding risk factors that associate with and predict the development of AUDs in PTSD could inform interventions and prevention efforts to reduce the rate of this comorbidity and improve outcomes of both disorders. Identifying predictor... Read More
Gender:
ALL
Ages:
Between 21 years and 60 years
Trial Updated:
03/27/2025
Locations: University of Texas at Austin, Austin, Texas
Conditions: Post-Traumatic Stress Disorder, Alcohol Drinking
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Recruiting
The purpose of this clinical trial is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs). The prospective randomized, double-blinded, sham-controlled trial is designed to demonstrate superiority of wound closure of the COMS One device to a sham-control device through 24 weeks post-application, when each is administered in conjunction with standard of care (SOC) in the treatment of DFUs.
Gender:
ALL
Ages:
Between 22 years and 90 years
Trial Updated:
03/27/2025
Locations: Richard C. Galperin DPM PA, Dallas, Texas
Conditions: Diabetic Foot Ulcer
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
Recruiting
This phase III trial compares the effect of 3 study approaches in preventing chemotherapy-induced peripheral neuropathy: 1) cryocompression, 2) continuous compression, and 3) low cyclic compression. Taxane chemotherapy drugs, such as paclitaxel or docetaxel, can cause a nerve disorder called peripheral neuropathy, which can cause numbness, tingling, or pain in the arms and legs. The 3 study approaches will use a device, called the Paxman Limb Cryocompression System, made of wraps that cool and/o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Conditions: Malignant Solid Neoplasm
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Recruiting
To learn about the effects of naproxen and aspirin on the normal colon in people with Lynch Syndrome.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: T Cells, Colorectal Cancer, Lynch Syndrome
Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors
Recruiting
This is a Phase 1/2, multicenter, open-label study to evaluate the safety and efficacy of IMP9064 as monotherapy or in combination with PARP inhibitor Senaparib in patients with advanced solid tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Mary Crowley Cancer Research Centers, Dallas, Texas
Conditions: Solid Tumor, Advanced Solid Tumor
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology
Recruiting
This study evaluates patient perceptions around quality of care through telemedicine in neuro-oncology. Studying questionnaires related to perceptions quality of care through telemedicine in patients with brain cancer may help doctors to improve the delivery of care through this modality.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Central Nervous System Neoplasm, Leptomeningeal Neoplasm, Metastatic Malignant Neoplasm in the Brain, Primary Brain Neoplasm
Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia
Recruiting
This trial investigates the experience and satisfaction of care in patients with cancer that has spread to other places in the body (advanced) and their caregivers living in underserved areas of Kenya, Nigeria, Ghana, South Africa, India and Ethiopia as part of Project Extension for Community Healthcare Outcomes (ECHO). Project ECHO is a model of medical education and care management that empowers clinicians to provide better care to more people where they live. Understanding the experiences and... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/27/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm
Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
Recruiting
Prospective will be collected in a minimum of 300 patients presenting with an acquired segmental mandibular defect ≥ 2 cm secondary to OSSC removal and drugs-induced osteonecrosis, and who require mandibular reconstruction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: John Peter Smith Health Network, Fort Worth, Texas
Conditions: Mandibular Reconstruction, Segmental Mandibular Defects
Neuromodulation and Neurorehabilitation for mTBI
Recruiting
This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing training (APT) when combined with intermittent theta burst stimulation (iTBS), a type of repetitive transcranial magnetic stimulation and (ii) determine how APT + iTBS changes the neurocognitive system of attention in individuals with persistent attention deficits related to mTBI +/- PTSD.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/27/2025
Locations: Moody Neurorehabilitation Institute, Houston, Texas
Conditions: Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Tranexamic Acid in Reducing Blood Loss in Patients With Pelvic Tumors Undergoing Hemipelvectomy Surgery
Recruiting
This early phase I trial studies how well tranexamic acid works in reducing the loss of blood in patients with pelvic tumors undergoing hemipelvectomy surgery. Tranexamic acid decreases blood loss by stabilizing clots and preventing clot lysis in patients undergoing surgery.
Gender:
ALL
Ages:
All
Trial Updated:
03/27/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Pelvic Mass