Texas is currently home to 4873 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
Recruiting
This First-in-Human (FIH) Phase 1/2 study is designed to characterize the safety, tolerability, and pharmacological activity (as assessed by biomarker measurements) and to determine the optimal dose of mRNA-3927 in participants with genetically confirmed propionic acidemia (PA). After establishing a dose with acceptable safety and pharmacodynamic (PD) response in a Dose Optimization Group (Part 1) in participants ≥1 year of age, additional participants will be enrolled into the study in a Dose E... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/26/2025
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Propionic Acidemia
Collection of Sputum and Labeling for Lung Cancer
Recruiting
The primary objective of this study is to compare Assay results to diagnoses determined by currently accepted standards for lung cancer detection. This will be accomplished by analysis of sputum samples from three cohorts including healthy Participants, high risk Participants, and cancer patient Participants using the Assay as developed in accordance with findings of bioAffinity protocol BA-001 to confirm assay results. Adjustments will be made as necessary to finalize Assay design for clinical... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/26/2025
Locations: South Texas Veterans Health Care System (STVHCS)/Audie L. Murphy Memorial Veterans Hospital, San Antonio, Texas
Conditions: Lung Cancer
Single Versus Multifraction Salvage Spine Stereotactic Radiosurgery for Previously Irradiated Spinal Metastases
Recruiting
The goal of this clinical research study is to learn whether delivering spine radiosurgery in a single large dose is better than delivering spine radiosurgery over 3 smaller doses. Researchers also want to learn about the effects of a single dose on participant's symptoms, pain, and quality-of-life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System
Metabolic Biomarkers in Thoracic Cancers
Recruiting
The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slight... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Lung Cancer
Supporting Informed Decision Making About Multi-cancer Early Detection Testing
Recruiting
To develop a new participant educational aid that can be used by participants to support informed decision-making about Multi-Cancer Early Detection (MCED) tests, which are new blood-based screening tests.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/25/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Multi-cancer Early Detection
The Effect of Uterine Entry in Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
Recruiting
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of chorioamniotic membrane separation.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Texas Children's Hospital - Pavilion for Women, Houston, Texas
Conditions: Twin to Twin Transfusion
Advancing Discussions Using a Video-based Support Tool About End-of-life Care
Recruiting
The purpose of this study is to evaluate the effectiveness and implementation considerations of a video aid to improve communication and patient-centered outcomes in older injured adults
Gender:
ALL
Ages:
65 years and above
Trial Updated:
03/25/2025
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Traumatic Injury
A Study to Assess Safety and Effectiveness of Injections of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Change of Mid-Face Volume
Recruiting
Facial fullness is often regarded as a characteristic feature of a youthful face. Chronic reduction of collagen, elastin, and glycosaminoglycans contribute to the facial volume loss that characterizes the aging face. Volume restoration by replacing or augmenting soft tissue is critical to successful facial rejuvenation. NOA VOLUME is a crosslinked Hyaluronic Acid (HA) gel implant formulated with lidocaine that was developed to provide a safe, minimally invasive method of improving mid-face volum... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: Westlake Dermatology & Cosmetic Surgery - Westlake /ID# 258156, Austin, Texas
Conditions: Mid Face Volume Deficit
An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: Rio Grande Regional Hospital, McAllen, Texas
Conditions: Heart Failure
Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe hypertriglyceridemia (SHTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo, and be evaluated for efficacy and safety. After Month 12, eligible participants will be offered an opportunity to continue in an optional open-label extension under a separate protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Diabetes and Thyroid Center of Fort Worth, Fort Worth, Texas
Conditions: Severe Hypertriglyceridemia
SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults with CD33 And/or FLT3 Blood Cancers Including AML/MDS
Recruiting
This is an open-label study of the safety, biodynamics, and anti-cancer activity of SENTI-202 (an off-the-shelf logic gated CAR NK cell therapy) in patients with CD33 and/or FLT3 expressing blood cancers, including AML and MDS.
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
03/25/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: AML/MDS, CD33 Expressing Hematological Malignancies, FLT3 Expressing Hematological Malignancies
Microphthalmia, Anophthalmia, and Coloboma Genetic Epidemiology in Children
Recruiting
The investigators are inviting families to take part in a research study that will help us better understand the physical characteristics associated with children who have Microphthalmia, Anophthalmia, and Coloboma (MAC) and how changes in their DNA sequence, called genetic mutations, play a role in the risk of developing MAC
Gender:
ALL
Ages:
All
Trial Updated:
03/25/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Microphthalmia, Coloboma, Anophthalmia