Texas is currently home to 4888 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients
Recruiting
The study will have two separate patient cohorts: Cohort 1 will include patients with newly diagnosed chronic graft versus host disease (GVHD), whereas cohort 2 will include patients with newly diagnosed chronic lung disease (CLD). For cohort 1, the primary objective will be to characterize PRM metrics at the onset of chronic GVHD and determine if a PRM signature is present that will predict 1-year CLD free survival. For cohort 2, the primary objective will focus on characterizing PRM at the ons... Read More
Gender:
ALL
Ages:
36 months and above
Trial Updated:
10/15/2024
Locations: MD Anderson, Houston, Texas
Conditions: Chronic Lung Disease, Hematopoietic Cell Transplantation, Graft Versus Host Disease
Vitamin D Deficiency in Adults Following a Major Burn Injury
Recruiting
This is a single site double blind randomized controlled trial of replacing Vitamin D for Vitamin D-deficient burn patients at a current recommended dose (400 IU daily) versus a higher dose (4000 IU daily). Capsules will be made in a compounding pharmacy and will look identical. Randomized controlled trial. People who meet the selection criteria will be randomized to either low or high dosage of Vitamin D. Treatment arm is high dose Vitamin D (4000 IU), and control is low dose Vitamin D (400 IU... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Parkland Health and Hospital Systems, Dallas, Texas
Conditions: Vitamin D Deficiency, Burns
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Recruiting
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib * Temozolomide (temodar) * Neratinib * CC115 * QBS10072S
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: UT MD Anderson Cancer Center, Houston, Texas
Conditions: Glioblastoma
Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care
Recruiting
The purpose of this study is to collect a large amount of data that may assist in addressing the gap in knowledge of understanding pupillometer readings using a pupillometer device. The aim of this project is to establish normative values for pupillometer data. Measures of central tendency will be developed for the variables provided by automated pupillary exams, which will provide an enhanced understanding of clinically appropriate pupil values for size, reactivity, and neurological pupil inde... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/15/2024
Locations: Maria E Denbow, Dallas, Texas
Conditions: Critical Illness, Neuropathy
Behavioral and Neural Correlates of Post-Stroke Fatigue
Recruiting
The goal of this phase I/II clinical trial is to determine the behavioral and neural effects of 5-daily transcranial direct current stimulation on post-stroke fatigue. The three aims are: Aim 1: Investigate the behavioral effect of 5 daily sessions of anodal tDCS over the ipsilesional M1 on PSF. Aim 2: Investigate the neurophysiological effect of 5 daily sessions of anodal tDCS over the ipsilesional M1. Aim 3: Determine the relationship between changes in M1 excitability, brain connectivity a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: Texas Woman's University, Dallas, Texas
Conditions: Stroke, Fatigue
CBD for Pain Following Orthopedic Shoulder Surgery
Recruiting
The goal of the study is to learn if Epidiolex (cannabidiol) works as a additional pain medication in patients who have had orthopedic shoulder surgery. It is also to learn about safe dosages and identify any side effects after surgery. Researchers will compare Epidiolex to a placebo solution to see if Epidiolex lowers pain after shoulder surgery. Participants will: * track their pain and what medications they use every day in a provided pain diary. A researchers will call every seven days to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Shoulder Osteoarthritis, Rotator Cuff Injuries
Impella RP Flex with Smart Assist
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: Medical City Heart Hospital Dallas, Dallas, Texas
Conditions: Right Ventricular (RV) Dysfunction
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
ALL
Ages:
Between 3 months and 18 years
Trial Updated:
10/09/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Pediatric Pulmonary Hypertension
Fall Risk and Quality of Life: in Individuals With Cancer Treatment Related Peripheral Neuropathy.
Recruiting
The purpose of this research is to examine the impact of peripheral neuropathy on fall risk and quality of life in people who had cancer and neuropathy from cancer treatments. The investigators are interested to find out if the participant have any difficulty with thinking, feeling, balancing, or moving around that will contribute to risk for falls or quality of life. Investigators are also interested to see if the participants have any difficulty with doing two activities at the same time, such... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Texas Woman's University, Dallas, Texas
Conditions: Peripheral Neuropathy Due to Chemotherapy
Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment
Recruiting
The objective of this trial is to determine if Near-infrared spectroscopy (NIRS) can accurately evaluate the degree of Peripheral Arterial Disease (PAD) during a Provocative Elevation Maneuver of the Lower Extremity (PEMLE) test, as compared to routine clinical assessments.
Gender:
ALL
Ages:
Between 35 years and 99 years
Trial Updated:
10/08/2024
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Peripheral Arterial Disease
Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the OASIS Trial
Recruiting
This clinical trial will investigate the effects of three surgical procedures and the associated post-operative rehabilitation to optimize time to return to military duty, work and sports, and patient-reported physical function for military personnel and civilians with traumatic anterior shoulder instability and 10-20% glenoid bone loss.
Gender:
ALL
Ages:
Between 17 years and 50 years
Trial Updated:
10/08/2024
Locations: San Antonio Military Medical Center, Fort Sam Houston, Texas
Conditions: Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
Testing FIRST in Youth Outpatient Psychotherapy
Recruiting
The study will compare the impact FIRST (a transdiagnostic treatment built upon five empirically supported principles of change) versus usual care outpatient psychotherapy on youths' mental health outcomes and a candidate mechanism of change: regulation of negative emotions.
Gender:
ALL
Ages:
Between 7 years and 15 years
Trial Updated:
10/08/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Anxiety, Depression, Trauma, Behavior Problem