Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Balance Control and Recovery in Diabetes Peripheral Neuropathy
Recruiting
In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults over 50 years. Aim 1: Determine muscle activity and balance control during a sit-to-stand in adults age above 50 with and without diabetic peripheral neuropathy. Aim 2: Assess local balance recovery and latency responses to lateral surface perturbation during quiet standing.
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
08/05/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2, Diabetic Peripheral Neuropathy Type 2 - Uncontrolled, Healthy Aging
PD, PK, and Safety of ALTO-203 in Patients With MDD
Recruiting
The goal of this clinical trial is to determine the pharmacodynamic effects of ALTO-203 in patients with MDD in a randomized, placebo-controlled, single-dose crossover treatment period. Additionally, safety, tolerability, and PK will be assessed in a subsequent randomized placebo-controlled multi-dose parallel-group treatment period of 28 days. Participants will complete subjective response questionnaires and perform cognitive tasks during the single-dose period, in which participants will rece... Read More
Gender:
ALL
Ages:
Between 25 years and 64 years
Trial Updated:
08/05/2024
Locations: Site 4040, Austin, Texas
Conditions: Major Depressive Disorder, Anhedonia
A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes
Recruiting
A randomized, double-blind, parallel-group, two-arm, multiple dose, multicenter, clinical endpoint bioequivalence study
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: Houston Eye Associates, Houston, Texas
Conditions: Open-angle Glaucoma, Ocular Hypertension
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies
Recruiting
This clinical trial is evaluating a drug called AC676 in participants with Relapsed/Refractory B-cell Malignancies. The main goals of the study are to: * Identify the recommended dose of AC676 that can be given safely to participants * Evaluate the safety profile of AC676 * Evaluate the pharmacokinetics of AC676 * Evaluate the effectiveness of AC676
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Relapsed/Refractory B-cell Malignancies
Clinical Assessment of Sports Exertion
Recruiting
The Clinical Assessment for Sports Exertion (CASE) addresses the physical performance of athletes by quantifying physiological and symptomatic responses to dynamic exertion. The CASE is highly sport-specific as it tests multiple body positions that mimic requirements typical of individual and contact sports activities including soccer, gymnastics, cheerleading, swimming, and basketball. It was developed by clinicians at the Baylor Scott and White Sports Concussion Program in an effort to identif... Read More
Gender:
ALL
Ages:
Between 10 years and 22 years
Trial Updated:
08/05/2024
Locations: Baylor Scott and White Sports Therapy and Research, Frisco, Texas
Conditions: Return to Sport
Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research
Recruiting
A major goal of this protocol is to support biomarker studies in advanced lung diseases, lung transplantation care, and to improve our understanding of the effects of viral and other infectious exposures to outcomes in our lung transplant and ALD patient populations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: Baylor Scott & White Research Institute, Dallas, Texas
Conditions: Respiratory Failure, Interstitial Lung Disease, Lung Diseases
A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
Recruiting
The goal of this clinical trial is to define a safe and effective dose of DM919 for participants with solid tumors The main questions it aims to answer are: What is the safe and effective dose of DM919 when used alone or in combination with pembrolizumab? What cancers can be treated effectively with DM919 alone or in combination with pembrolizumab?? Participants will be asked to attend clinic and be given a intravenous infusion of DM919 or DM-919 in combination with pembrolizumab. They will h... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2024
Locations: NEXT Oncology, San Antonio, Texas
Conditions: Advanced Solid Tumor
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MKND-201 in Healthy Volunteers
Recruiting
MKC-NI-001 is a Phase 1, first-in-human, randomized, double-blind, placebo-controlled study of nintedanib inhalation powder (MNKD-201) in healthy adult volunteers. The trial consists of a Single Ascending Dose (SAD), followed by a Multiple Ascending Dose (MAD) with a primary objective to evaluate the safety, tolerability, and pharmacokinetics (PK) of MNKD-201 compared to placebo in healthy adult participants.
Gender:
ALL
Ages:
Between 40 years and 65 years
Trial Updated:
08/02/2024
Locations: Flourish Research, San Antonio, Texas
Conditions: Healthy Volunteers
Annatto-derived GG for Statin-associated Myopathy
Recruiting
To evaluate the effects of 3-months annatto-derived geranylgeraniol (GG) supplementation on statin-associated skeletal muscle health.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
08/02/2024
Locations: Texas Tech University Health Sciences Center, Lubbock, Texas
Conditions: Myopathy; Primary
OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages
Recruiting
The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an i... Read More
Gender:
ALL
Ages:
3 years and above
Trial Updated:
08/02/2024
Locations: Baylor College of Medicine & Texas Children's Hospital, Houston, Texas
Conditions: Eosinophilic Gastrointestinal Disorders (EGIDs), Eosinophilic Esophagitis, Eosinophilic Colitis, Eosinophilic Gastritis, Eosinophilic Gastroenteritis
Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation
Recruiting
This study will examine how effective caregiver's repositioning strategies are in correcting an infant's deformational cranial shape, as well as the effectiveness of the use of a custom cranial remolding orthosis for treatment of deformational head shapes. Infants with torticollis will be concurrently enrolled in physical therapy treatment until the torticollis is resolved. A normal, unaffected population will be studied to compare typical growth to the growth of infants undergoing active treatm... Read More
Gender:
ALL
Ages:
Between 2 months and 3 months
Trial Updated:
08/01/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Deformational Plagiocephaly, Deformational Posterior Plagiocephaly, Brachycephaly, Torticollis, Congenital Muscular Torticollis
Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)
Recruiting
Langerhans Cell Histiocytosis (LCH) is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis (LCH) is a cancer that begins in LCH cells (a type of dendritic cell which fights infection). Sometimes there are mutations (changes) in LCH cells as they form. These include mutations of the BRAF gene. These changes may make the LCH cells grow and multiply quickly. This causes LCH cells to build up in certain parts of the body,... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
08/01/2024
Locations: Dell Children's Medical Center, Austin, Texas
Conditions: Langerhans Cell Histiocytosis