Texas is currently home to 4888 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
Recruiting
Low blood sugars are known to cause brain damage in newborn babies. One of the most common causes of low blood sugars persisting beyond the new born period is a condition called congenital hyperinsulinism (HI). This is a disease whereby the pancreas secretes too much insulin and causes low blood sugars. Twenty to forty percent of these babies will have brain damage. There are two forms of this disease. In one form only a small part of the pancreas makes too much insulin (focal HI) and in the oth... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
07/15/2024
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Congenital Hyperinsulinism, Insulinoma
BiVACOR® Total Artificial Heart Early Feasibility Study
Recruiting
The purpose of this study is to assess the feasibility of using the BiVACOR Total Artificial Heart (TAH) System to support adult patients with severe biventricular heart failure, or univentricular heart failure in which left ventricular assist device (LVAD) support is not recommended, who require mechanical circulatory support to sustain life. The BiVACOR TAH System is intended for use as a bridge to transplant (BTT). Feasibility will be assessed by evaluating safety and performance of the BiVAC... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/12/2024
Locations: Texas Heart Institute / Baylor St. Luke's Medical Center, Houston, Texas
Conditions: Heart Failure, Biventricular Failure
Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations
Recruiting
The PI and the research team developed the New York University (NYU) Electronic Patient Visit Assessment (ePVA) for head and neck cancer (HNC) as a patient-reported outcome measure (PRO) for the early detection of uncontrolled symptoms. The ePVA is digital patient-reported symptom monitoring system, providing actionable information at point-of-care that enables clinicians to provide real-time interventions. The study aims to advance the science of cancer care delivery by testing the effectivenes... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: UTHealth Houston Cizik School of Nursing, Houston, Texas
Conditions: Head and Neck Cancer
A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment
Recruiting
The purpose of this study is to assess the drug levels of a single oral dose of repotrectinib in participants with moderate and severe HI, and in healthy matched control participants with normal hepatic function.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/10/2024
Locations: Local Institution - 0004, San Antonio, Texas
Conditions: Hepatic Impairment, Healthy Volunteers
Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform
Recruiting
The primary objective of this study is to determine the ex-vivo prognostic accuracy of the Cybrid live tumor diagnostic platform using in-vivo RECIST 1.1 as the reference method.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: JPS Health Network, Fort Worth, Texas
Conditions: Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer, NSCLC, Metastatic NSCLC - Non-Small Cell Lung Cancer
TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence
Recruiting
Multi-center open-label randomized controlled trial to assess if early intervention (12.0-14.0 weeks) (study group) improves the outcome of TRAP sequence as compared to late intervention (16.0-19.0 weeks) (control group). The investigators will randomly assign women diagnosed with TRAP sequence diagnosed between 12.0 and 13.6 weeks to an early or late intervention group (1:1), using a web-based application and a computer-generated list with random permuted blocks of sizes 2 or 4 (www.sealedenvel... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/09/2024
Locations: Children's Memorial Hermann Hospital, Houston, Texas
Conditions: Twin Reversal Arterial Perfusion Syndrome
Fluid Loading Countermeasures
Recruiting
The purpose of Fluid Loading Countermeasures is to determine how the volume of blood and of plasma (liquid part of blood) change during a normal day, how these are affected by drinking an additional amount of fluid either as water and salt tablets (as astronauts do) or an electrolyte beverage (similar to but tastes saltier than Gatorade®), and how altering the timing at which the additional fluid is consumed affects blood and plasma volume. This study observes how blood volume changes over \~9 h... Read More
Gender:
ALL
Ages:
Between 25 years and 55 years
Trial Updated:
07/08/2024
Locations: NASA, Houston, Texas
Conditions: Healthy
Paper-Based and Smartphone-Based Memory Supports
Recruiting
Alzheimer's disease and related dementias lead to marked declines in daily functioning, independence, and quality of life. One of the earliest cognitive changes in these conditions is impairment in prospective memory, or the ability to remember future intentions such as taking medications at a given time. Prior intervention studies that targeted prospective memory used mnemonic strategies or cognitive training, but these approaches resulted in modest gains in clinical populations. By contrast, a... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
07/08/2024
Locations: UT Health Austin Comprehensive Memory Center, Austin, Texas
Conditions: Alzheimer Disease, Dementia, Mild, Mild Cognitive Impairment
Lutein, Zeaxathin, and Fish Oil Supplementation
Recruiting
The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults. The main question it aims to answer is: Will supplementation with LZF improve macular pigment optical density (MPOD), cognitive performance and bone mass compared to controls after six months? Subjects with an MPOD \<.43 will significantly improve MPOD after 6-months of LZF supplementation. Consuming a LZFO supplement for 6-months will improve visual cognitive pe... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
07/05/2024
Locations: Gilchrist Building, College Station, Texas
Conditions: Cognitive Performance, Age-Related Macular Degeneration, Bone Loss
67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma
Recruiting
The aim of this study is to evaluate the safety and efficacy of 67Cu-SARTATE in pediatric patients with high-risk neuroblastoma.
Gender:
ALL
Ages:
All
Trial Updated:
07/05/2024
Locations: University of Texas Southwestern Medical Centre, Dallas, Texas
Conditions: Neuroblastoma, Relapsed Neuroblastoma, Refractory Neuroblastoma
Psychotherapy Effects on Reward Processing in PTSD
Recruiting
The purpose of this study is to identify how trauma-focused psychotherapy changes the function of brain circuitry in posttraumatic stress disorder (PTSD) and how this mediates improvements in the diminished ability to experience positive emotions following a traumatic or extremely stressful life event. In this instance, the investigators will be using cognitive processing therapy (CPT), a widely-utilized and evidence-based treatment for PTSD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/04/2024
Locations: Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin, Texas
Conditions: Post Traumatic Stress Disorder, Diminished Pleasure, Anhedonia, PTSD, Chronic PTSD, Chronic Post-Traumatic Stress Disorder
Optimizing Intervention Options for Toddlers With Early Social Communication Delays
Recruiting
Improving social communication outcomes for toddler siblings of children with autism, who are at high risk for multiple language and communication deficits beyond autism, has important public health implications. The proposed study is a pilot sequential multiple random assignment trial of 44 high-risk siblings that examines the feasibility, acceptability, and preliminary effects of an adaptive intervention for social communication. Evaluating effective parent-mediated communication support strat... Read More
Gender:
ALL
Ages:
Between 11 months and 18 months
Trial Updated:
07/03/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Autism Sibling