Texas is currently home to 4879 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies
Recruiting
Pancreatic cystic lesions (PCLs) are a common incidental finding in cross sectional imaging (up to 27% on CT scan and 41% on MRI) and pose a management challenge to physicians. According to society guidelines, PCLs with specific features should prompt additional workup with endoscopic ultrasound (EUS) for cyst characterization as well as cyst sampling. This can help determine if the cyst is mucinous or non-mucinous which has implications for its malignant potential. Cyst fluid has traditionally... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/20/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Pancreatic Cyst
Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies
Recruiting
This clinical trial is a Phase 1-2, open-label, sequential-group, dose-escalation and cohort-expansion study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor activity of Zotatifin (eFT226) in subjects with selected advanced solid tumor malignancies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Solid Tumor, Adult
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
Recruiting
Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring normal rhythm (NR) which may be because current surveillance is limited to once- weekly fetal echocardiograms. It is hypothesized that there may be a vital transition p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: AVB - Atrioventricular Block, Fetal AVB
Histological Evaluation in the Efficacy of GentleWave in Root Canal Pulp Tissue Debridement and Disinfection of Difficult to Reach Areas in Mandibular Human Molars II. An In-vivo Study.
Recruiting
The purpose of this study is to understand and learn better the efficacy of GentleWave and obtain histological evidence of the efficacy of this new technology done in-vivo
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/17/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Root Canal Treatment
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
Recruiting
The primary specific aim is to evaluate the use of intranasal scopolamine gel and sensory augmentation as an integrated countermeasure to mitigate motion sickness and enhance sensorimotor performance. The proposed intranasal scopolamine gel formulation (Defender Pharmaceuticals, Inc.) offers a safe non-invasive method to self-administer with a rapid onset of action. This study involves a comparison of motion sickness outcome measures when administering intranasal scopolamine gel versus placebo (... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/15/2024
Locations: NASA Johnson Space Center Neuroscience Laboratory, Houston, Texas
Conditions: Motion Sickness, Space, Motion Sickness, Sea Sickness
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
Recruiting
The primary specific aim of this Field Test aim is to evaluate the feasibility and efficacy of administering the intranasal scopolamine gel in operational field settings using both astronaut and ground-control subjects that are exposed to provocative motion as part of their assigned duties. For the ground-control subjects, these may include motion simulations (e.g., centrifuge), parabolic flights and/or Orion capsule recovery operations. Astronaut participants may choose to test Inscop during pr... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/15/2024
Locations: NASA Johnson Space Center Neuroscience Laboratory, Houston, Texas
Conditions: Motion Sickness, Space, Motion Simulation, Parabolic Flight
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Recruiting
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (G... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/15/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Motor Function, Cognitive Function, Contrast Media
Community Opioid Innovation Network (JCOIN): TCU Clinical Research Center
Recruiting
There are two study periods for the TCU JCOIN project. The primary aims of Study 1 (approved by the TCU IRB) are (1) to gather information from staff on the current treatment referral process within participating communities and (2) to learn about the existing interrelationships between medical and community behavioral health (CBH) providers. TCU IRB granted approval for Phase 1 on 11/07/19, approval number: 1920-60-AM1. Study 2 (under current review by the TCU IRB) includes recruitment across 1... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: Texas Christian University, Fort Worth, Texas
Conditions: Addiction, Opioid
Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma
Recruiting
Microneedling radiofrequency technology has been shown in clinical studies to improve skin quality, tone, pigment, and to treat various skin conditions related to aging. The purpose of this study is to evaluate efficacy and safety of Sylfrim X device for the treatment of melasma.
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
05/14/2024
Locations: Refresh Dermatology, Houston, Texas
Conditions: Melasma
Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production
Recruiting
This is a split-face, single-blind study assessing the use of an antioxidant serum with a series of acne laser treatments to reduce sebum production in healthy male and female subjects between the ages of 18 and 65 years, inclusive, with Fitzpatrick skin types I-VI.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/14/2024
Locations: Austin Institute for Clinical Research, Inc., Pflugerville, Texas
Conditions: Acne
An Adjunct Test Distinguishing Bacterial From Viral Etiology Improves Resource Utilization and Efficiency in the ED.
Recruiting
The purpose of this study is to evaluate overall changes in patient management and longer-term resource utilization between control and test arms, including (but not limited to) additional work-up (including other diagnostic tests and consults), antimicrobial treatments, disposition decisions and hospital length of stay (LOS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Respiratory Tract Infections
Comparative Performance of a Vaginal Yeast Test
Recruiting
The purpose of this study is to establish lay user performance criteria for the SavvyCheck Vaginal Yeast Test in comparison to standard vaginal yeast culture and identification method for Candida (the Reference Method). Polymerase chain reaction (PCR) and sequencing of fungi will be used as an aid to explain the nature of the discrepancy in the case of discordant results between the lay user-performed SavvyCheck Vaginal Yeast Test and standard vaginal yeast culture and identification method for... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: Brooke Army Medical Center, Fort Sam Houston, Texas
Conditions: Vulvovaginal Candidiasis