Texas is currently home to 4881 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: St. David's South Austin Medical Center, Austin, Texas
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome
Recruiting
Single center, prospective, randomized, double-blind, pragmatic Phase 2 clinical study in severely injured trauma patients within hours of hospitalization who have survived initial resuscitation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: Healios Investigational Site, Houston, Texas
Conditions: Trauma, Adult Stem Cells
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
Recruiting
Heart failure (HF) with preserved left ventricular function (pEF) is difficult clinical syndrome to treat effectively with few evidence based therapies. Atrial fibrillation (AF) is now an important co-morbidity being observed in 43% of patients with HFpEF. Rhythm control has not been studied in this population. Catheter ablation and antiarrhythmic drugs are rhythm control therapies that have been used for treatment of AF without HF or HF with reduced systolic function but have not been widely ap... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/22/2024
Locations: TCAI at St. David's Hospital, Austin, Texas
Conditions: Atrial Fibrillation, Heart Failure, Diastolic Heart Failure
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Recruiting
The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulatory hemodynamics monitoring and HF (Heart Failure) therapies. The data collected will be used for retrospective studies, quality improvement, identifying research cohorts, and member-initiated research.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/21/2024
Locations: Austin Heart, Austin, Texas
Conditions: Heart Failure
An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
Recruiting
Open-label study of brexanolone infusion for the treatment of posttraumatic stress disorder in 20 adult women with PTSD. Primary Objective: To determine if brexanolone injection infused intravenously for 24 hours at up to 60 μg/kg/h reduces PTSD symptom severity in a group of non-veteran adult female subjects diagnosed with PTSD as assessed by the change from baseline in the PTSD Checklist for DSM-5 (PCL-5) total score and rate of remission at 12-weeks post infusion. Secondary Objectives * T... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/21/2024
Locations: University of Texas at Austin Dell Medical School, Austin, Texas
Conditions: Post-Traumatic Stress Disorder
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block
Recruiting
Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally slow heart rate due to maternal antibody-mediated heart disease in the unborn baby (fetus). Since the late seventies, it has been possible to detect and monitor fetal disease by ultrasound images and to treat selected conditions with pharma... Read More
Gender:
FEMALE
Ages:
Between 16 years and 50 years
Trial Updated:
05/21/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Heart Block Complete, Heart Block Second Degree
Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane
Recruiting
The purpose of this protocol is to determine the effect of two clinically applicable Dexmedetomidine dosages (0.5mcg/kg and 1mcg/kg) on the minimum alveolar concentration (MAC) of Sevoflurane in children between the age ranges of: 1-6 months; 6-12 months of age and 12 months-36 months years of age.
Gender:
ALL
Ages:
Between 1 month and 36 months
Trial Updated:
05/21/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Pediatric Anesthesia
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Recruiting
Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%. The most common associated amblyogenic risk factors are uncorrected anisometropia, strabismus, or a combination of these. In addition to reduced visual acuity, amblyopic patients may also have measurable dysfunction of accommodation, fixation, binocularity, vergence, reading fluency, depth perception, and contrast sensitivity. For the first t... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/20/2024
Locations: Pediatric Eye Specialist, Fort Worth, Texas
Conditions: Amblyopia
Enhancing Food as Medicine Interventions for Food Insecure Postpartum Women in Central Texas
Recruiting
The purpose of this study is to compare the short-term and long term impacts of Food is the Best Medicine (FBM)-Virtual on diet quality, food security status, breastfeeding rates, mental health status, rates of home cooking, and rationing coping strategies relative to FBM-In Person among food insecure, postpartum women and to compare implementation outcomes across the FBM-Virtual and FBM-In Person using process data collected from the participants, Community Health Worker (CHW)s, and partner org... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/20/2024
Locations: Ascension Seton Medical Center, Austin, Texas
Conditions: Food Insecurity in Post Partum Women
KIOS Mobile App Evaluation
Recruiting
Evaluation of a mobile medical app (KIOS) vs. treatment as usual for the treatment of opioid use disorder (OUD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: University of Texas Health Science Center - Department of Psychiatry, San Antonio, Texas
Conditions: Opioid Use Disorder
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
Recruiting
A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Texas Oncology - Tyler, Tyler, Texas
Conditions: Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor, Recurrent Endometrial Carcinoma, Endometrioid Endometrial Cancer
Intraoperative Exercises & Musculoskeletal Pain in Gynecologic Surgeons
Recruiting
The goal of this study is to evaluate the effect of intraoperative microbreaks and exercises on gynecologic surgeon body discomfort by conducting a randomized trial. We hypothesize that gynecologic surgeons will experience decreased pain on surgery days with intraoperative microbreaks and exercises without compromising overall surgical performance.
Gender:
ALL
Ages:
All
Trial Updated:
05/20/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Work-related Injury, Physical Injury