Texas is currently home to 4860 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD)
Recruiting
The purpose of this study is to assess acceptability, and safety of providing tDCS to ADRD patients with behavioral symptoms and to assess the efficacy of tDCS for ADRD-related symptoms, mainly behavioral symptoms.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/24/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Alzheimer Disease
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma
Recruiting
This is a 2-part, phase 1/2, open-label, multicenter study designed to evaluate the safety, tolerability, PK, pharmacodynamics, PGx, and efficacy of fadraciclib administered orally BID. This study consists of Phase 1 and Phase 2 components in subjects with advanced solid tumors and lymphoma who have progressed despite having standard therapy or for which no standard therapy exists.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Solid Tumor, Adult, Lymphoma
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Texas Clinical Research Institute, Arlington, Texas
Conditions: NASH - Nonalcoholic Steatohepatitis
Study of CBP-4888 in Healthy, Non-Pregnant Female Subjects
Recruiting
This is a Phase I, first-in-human, single-center, randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, tolerability, and PK of ascending doses of CBP-4888.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
01/23/2024
Locations: Comanche Biopharma Clinical Research Site #1, San Antonio, Texas
Conditions: Healthy Volunteer Study
Marfan Syndrome Moderate Exercise Trial II
Recruiting
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given limited evidence from in-vitro studies, and theoretical concerns, the majority of patients with MFS are restricted from certain physical activities. The lack of exercise and deconditioning have detrimental effects including increasing weakness, joint pain, decreased endurance, and... Read More
Gender:
ALL
Ages:
Between 10 years and 25 years
Trial Updated:
01/23/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Marfan Syndrome
Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
Recruiting
The purpose of this study is to examine the effects of pioglitazone on stress-induced relapse risk in a laboratory model and to examine the effects of pioglitazone on drinking, stress/anxiety, and alcohol craving in the natural environment
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: The University of Texas Health Science Center of Houston, Houston, Texas
Conditions: Alcohol Use Disorder
A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression
Recruiting
The purpose of this study is to o evaluate the antidepressant efficacy of the PEA in Bipolar Depression and the association between antidepressant response with endogenous cannabinoids and cytokine levels
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/19/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Bipolar Depression
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury
Recruiting
It has been demonstrated that the human lumbosacral spinal cord can be neuromodulated with epidural (ESS) and transcutaneous (TSS) spinal cord stimulation to enable recovery of standing and volitional control of the lower limbs after complete motor paralysis due to spinal cord injury (SCI). The work proposed herein will examine and identify distinct electrophysiological mechanisms underlying transcutaneous spinal stimulation (TSS) and epidural spinal stimulation (ESS) to define how these approac... Read More
Gender:
ALL
Ages:
Between 22 years and 60 years
Trial Updated:
01/18/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Spinal Cord Injuries, Neuromodulation
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
Recruiting
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate. The main questions it aims to answer are: * Are there tissue thickness changes between the two groups (control group and augmentation group)? * Are there volumetric changes in the donor site (palate) between the two groups in the short and long term? Participants will receive... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/17/2024
Locations: Texas A&M College of Dentistry, Dallas, Texas
Conditions: Recession, Gingival
Establishing the Chaplain Role in a Primary Care Clinic Setting
Recruiting
In 2019, a full-time chaplain was placed in the Golden Cross Academic Clinic (GCAC), with the chaplain's focus being in the primary care internal medicine department. While research exists regarding chaplains in the inpatient setting, research regarding the presence of a full-time chaplain in a primary care setting as well as the topics patients discuss with that chaplain are limited.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/16/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Emotional Disorder
Review of Breast Abscess Management
Recruiting
Breast abscesses are an unfortunate pathology that develop in patients, and treatment is often painful and unpleasant. The goal of this study is to identify risk factors associated with failure of aspiration as a primary intervention as opposed to incision and drainage in the hopes of adequately treating patients at initial presentation.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/16/2024
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Breast Abscess