Texas is currently home to 5040 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study Of The Selective PKC-β Inhibitor MS- 553
Recruiting
A Phase I/II Dose-Escalation and Expansion Study Of The Selective PKC-Î’ Inhibitor MS-553 In Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2023
Locations: MD Anderson Cancer Center, Department of Leukemia, Houston, Texas
Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Aggressive Lymphoma
A Study of ICP-192 in Patients With Advanced Solid Tumors
Recruiting
This is a multi-center, open-label, phase I/II clinical study to evaluate ICP-192 in patients with advanced solid tumors and FGFR gene alterations. It consists of two parts: Part I (Phase I), dose escalation and Part II (Phase II), dose expansion.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/12/2023
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced Solid Tumors, Urothelial Carcinoma, Cholangiocarcinoma
Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites
Recruiting
A Multicenter Study Conducted to Evaluate the Performance of the LumiraDx Influenza A/B + RSV Test at Point of Care Testing Sites
Gender:
All
Ages:
All
Trial Updated:
03/10/2023
Locations: Family Medical Associates, Carrollton, Texas
Conditions: Influenza, Human, Respiratory Syncytial Virus Infections
EyeKon Medical Inc. Capsular Tension Ring Study
Recruiting
This study evaluates the safety and effectiveness of a capsular tension ring (CTR) when used during cataract surgery. Capsular Tension Rings are used during intraocular lens implantation to give added support in order to keep the intraocular lens well centered, especially in eyes with weak or partially absent zonules. In many cases, capsular tension rings allow a lens to be successfully implanted into an eye which otherwise could not have supported an intraocular lens.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/10/2023
Locations: Brazosport Eye Institute, Lake Jackson, Texas
Conditions: Cataract Extraction
A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies
Recruiting
This study will be divided into two parts, Parts A and B and will enroll patients with relapsed/refractory AML or MDS/chronic myelomonocytic leukemia (CMML) patients who have failed up to 2 prior therapeutic regimens. Part A is a dose escalation study to explore the safety, efficacy, pharmacokinetic (PK) and pharmacodynamic (PD) profile of DSP107 when administered in combination with azacitidine (AZA). Part B is a dose escalation study to explore the safety, efficacy, PK and PD profile of DSP1... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/09/2023
Locations: The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, Texas
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia
Artificial Intelligence Mobile Health Trial Of A Digital Platform To Optimize GDMT Using Wearable Sensors
Recruiting
The goal of this real-world, multi-center, randomized, outpatient study is to assess the effectiveness of the Biofourmis cloud based BiovitalsHFTM platform to recommend optimal titration of Guideline-Directed Medical Therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) subjects.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/09/2023
Locations: Austin Heart, San Marcos, Texas
Conditions: Heart Failure
PF-07104091 as a Single Agent and in Combination Therapy
Recruiting
To assess the safety and tolerability of increasing doses of PF-07104091 and to estimate the Maximum Tolerated Dose (MTD) and/or select the Recommended Phase 2 dose (RP2D) for PF-07104091 as a single agent in participants with advanced or metastatic small cell lung, breast and ovarian cancers.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2023
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer
Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy
Recruiting
The purpose of this study is to evaluate whether Continuous glucose monitoring (CGM) for diagnosis of gestational diabetes mellitus (GDM) improves maternal and neonatal outcomes related to GDM and to evaluate whether CGM for GDM diagnosis reduces the health system costs for mother-infant dyads compared to usual care
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/07/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Gestational Diabetes
ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors
Recruiting
ACE1702 (anti-HER2 oNK cells) is an off-the-shelf Natural Killer (NK) cell product that targets human HER2-expressing solid tumors. The ACE1702-001 phase I study aims to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of ACE1702 in patients with advanced or metastatic HER2-expressing tumors, and to determine the phase Ib/II starting dose for ACE1702.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Locally Advanced Solid Tumor, Metastatic Cancer, Solid Tumor, HER2-positive Gastric Cancer, HER2-positive Metastatic Breast Cancer
SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects
Recruiting
This is a Phase 1/2a randomized, double-blind, two-part, dose-ascending, multicenter study of AR-501 (gallium citrate) solution, administered via inhalation, in healthy adult and P. aeruginosa infected cystic fibrosis (CF) subjects. Phase 1 of the study in HV subjects will consist of a single-ascending-dose (SAD) cohort, followed by the HV multiple-ascending-dose (MAD) cohort. Phase 2a of the study in CF subjects will consist of a MAD study design. The study will evaluate the safety and pharmaco... Read More
Gender:
All
Ages:
Between 18 years and 49 years
Trial Updated:
03/07/2023
Locations: Research Site, Tyler, Texas
Conditions: Cystic Fibrosis
PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)
Recruiting
The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation procedures of high-energy lower extremity fractures (HELEF) will decrease the patients' risk of surgical site infections (SSI), particularly those caused by Staphylococcus aureus.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2023
Locations: University of Texas Southwestern, Dallas, Texas
Conditions: Surgical Site Infection
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Recruiting
Children and adults diagnosed with high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow will be treated for up to 101 weeks with naxitamab and granulocyte-macrophage colony stimulating factor (GM-CSF). Patients will be followed for up to five years after first dose. Naxitamab, also known as hu3F8 is a humanised monoclonal antibody targeting GD2
Gender:
All
Ages:
1 year and above
Trial Updated:
03/06/2023
Locations: M.D. Anderson Cancer Center, Houston, Texas
Conditions: Neuroblastoma