Texas is currently home to 4884 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Texas Clinical Research Institute, Arlington, Texas
Conditions: NASH - Nonalcoholic Steatohepatitis
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Study of CBP-4888 in Healthy, Non-Pregnant Female Subjects
NCT05881993
Recruiting
This is a Phase I, first-in-human, single-center, randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, tolerability, and PK of ascending doses of CBP-4888.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
01/23/2024
Locations: Comanche Biopharma Clinical Research Site #1, San Antonio, Texas
Conditions: Healthy Volunteer Study
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Marfan Syndrome Moderate Exercise Trial II
NCT05809323
Recruiting
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection. Given limited evidence from in-vitro studies, and theoretical concerns, the majority of patients with MFS are restricted from certain physical activities. The lack of exercise and deconditioning have detrimental effects including increasing weakness, joint pain, decreased endurance, and... Read More
Gender:
ALL
Ages:
Between 10 years and 25 years
Trial Updated:
01/23/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Marfan Syndrome
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Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
NCT05107765
Recruiting
The purpose of this study is to examine the effects of pioglitazone on stress-induced relapse risk in a laboratory model and to examine the effects of pioglitazone on drinking, stress/anxiety, and alcohol craving in the natural environment
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: The University of Texas Health Science Center of Houston, Houston, Texas
Conditions: Alcohol Use Disorder
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Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury
NCT06213012
Recruiting
It has been demonstrated that the human lumbosacral spinal cord can be neuromodulated with epidural (ESS) and transcutaneous (TSS) spinal cord stimulation to enable recovery of standing and volitional control of the lower limbs after complete motor paralysis due to spinal cord injury (SCI). The work proposed herein will examine and identify distinct electrophysiological mechanisms underlying transcutaneous spinal stimulation (TSS) and epidural spinal stimulation (ESS) to define how these approac... Read More
Gender:
ALL
Ages:
Between 22 years and 60 years
Trial Updated:
01/18/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Spinal Cord Injuries, Neuromodulation
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Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
NCT05961566
Recruiting
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate. The main questions it aims to answer are: * Are there tissue thickness changes between the two groups (control group and augmentation group)? * Are there volumetric changes in the donor site (palate) between the two groups in the short and long term? Participants will receive... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/17/2024
Locations: Texas A&M College of Dentistry, Dallas, Texas
Conditions: Recession, Gingival
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Establishing the Chaplain Role in a Primary Care Clinic Setting
NCT06225219
Recruiting
In 2019, a full-time chaplain was placed in the Golden Cross Academic Clinic (GCAC), with the chaplain's focus being in the primary care internal medicine department. While research exists regarding chaplains in the inpatient setting, research regarding the presence of a full-time chaplain in a primary care setting as well as the topics patients discuss with that chaplain are limited.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/16/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Emotional Disorder
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Review of Breast Abscess Management
NCT06225180
Recruiting
Breast abscesses are an unfortunate pathology that develop in patients, and treatment is often painful and unpleasant. The goal of this study is to identify risk factors associated with failure of aspiration as a primary intervention as opposed to incision and drainage in the hopes of adequately treating patients at initial presentation.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/16/2024
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Breast Abscess
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Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia
NCT06223607
Recruiting
The use of clopidogrel as part of DAPT will be associated with lower bleeding rates compared to ticagrelor in patients with chronic thrombocytopenia requiring Percutaneous intervention (PCI )with Drug Eluting Stent (DES) or Bare Metal Stint(BMS).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Baseline Thrombocytopenia
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Evaluation of Intravenous Fluid Therapy Within Dallas Acute Pancreatitis Protocol
NCT06223594
Recruiting
Acute pancreatitis (AP) is a common disease of the gastrointestinal tract that can result in emotional, physical, and financial burdens on the patient.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/16/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Acute Pancreatitis
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Massive Transfusion in Trauma Patient Registry
NCT06136715
Recruiting
The early use of blood products as a part of Massive Transfusion Protocol (MTP) during trauma resuscitation has been increasingly supported by providers and backed by the literature. However, the incidence of hypocalcemia during MTP has also been recorded and continues to be studied as an exacerbating factor in coagulopathy during trauma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Trauma
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Decreasing Post-Operative Nausea and Vomiting in the Bariatric Surgical Patient
NCT06110416
Recruiting
From the research and current studies, post-operative nausea and vomiting is a common complaint after bariatric surgery. Nausea relief inhalers could improve post-operative nausea and vomiting without the need for further medications, subsequently reducing the chance of side effects. This study could help improve patient satisfaction and increase the ability of the patient to ambulate after surgery with the use of a nausea relief inhaler.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/16/2024
Locations: Methodist Mansfield Medical Center, Mansfield, Texas
Conditions: Nausea, Postoperative, Vomiting, Postoperative
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