Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Texas Retina Associates, Dallas, Texas
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
Substance Abuse Pre-Treatment Screening Study
Recruiting
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/19/2023
Locations: University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute, Houston, Texas
Conditions: Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Open Nipple Sparing Mastectomy (NSM)
Recruiting
This is retrospective, multicenter chart review is to evaluate the complication rates of prophylactic open NSM procedures through 42 days postoperatively
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/17/2023
Locations: Univ. of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Nipple Sparing Mastectomy
Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Recruiting
This is a phase 1, multi-center, open-label, dose-escalation study of nab-sirolimus in adult patients with locally advanced or metastatic solid tumors and moderate hepatic impairment or normal hepatic function.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas
Conditions: Tumor, Solid, Tumor, Advanced Solid Tumor
Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants
Recruiting
The main purpose of this study is to measure the efficacy of farudodstat compared to placebo at Week 12 from the treatment start, in adult participants with Alopecia Areata (AA) with 30% or greater scalp hair loss.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: 1 Site, Pflugerville, Texas
Conditions: Alopecia Areata
A Trauma-Informed Sleep Intervention for Children in Foster Care
Recruiting
Sleep disturbances are pervasive and impairing among children who spend time in foster care but not a single prevention or intervention program for this fragile group targets sleep health. Poor sleep undermines effective self-regulation and stable biological rhythms, amplifying the negative impacts of early adversity/trauma on immediate and long-term functioning. Consistent with evidence that optimizing sleep is critical for trauma recovery, the investigators will adapt cognitive-behavioral trea... Read More
Gender:
ALL
Ages:
Between 6 years and 10 years
Trial Updated:
12/12/2023
Locations: Sleep and Anxiety Center of Houston, Houston, Texas
Conditions: Sleep Disturbance, Child Development, Mental Disorder, Child
Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas
Recruiting
The purpose of this study is to assess the baseline sleep pattern disruption for patients starting oral propranolol at the standard BID dosing regimen compared to the control (timolol) group and to determine if there is a significant improvement in the sleep patterns in infants taking oral propranolol on the TID dosing regimen versus the control (timolol) group
Gender:
ALL
Ages:
18 months and below
Trial Updated:
12/08/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Infantile Hemangioma
Ultrasound Imaging and Spectroscopy as Early Indicators of Locally-Advanced Breast Cancer Response
Recruiting
This work explores the possibility of using ultrasound imaging and spectroscopy as a way of monitoring cell death, hence, tumour response to treatment. The hypothesis here is that it can be used as a way of monitoring early response to cancer treatment and predicting which patients continue on in their therapy to have a complete pathological response as a primary endpoint and tumour size decrease as a secondary endpoint. If this work is successful it could be used in the future early on in a can... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/07/2023
Locations: MD Anderson, Houston, Texas
Conditions: Breast Cancer
Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: DermResearch, Austin, Texas
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
Recruiting
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
Gender:
ALL
Ages:
Between 55 years and 80 years
Trial Updated:
12/06/2023
Locations: University of North Texas Health Science Center, Fort Worth, Texas
Conditions: Aging Well, Walking, Difficulty, Hyperemia
Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
Recruiting
This study will assess the safety and efficacy of increasing doses of narazaciclib (ON 123300) in combination with the standard daily dose (2.5mg) of letrozole in patients with Recurrent Metastatic Low-grade Endometrioid Endometrial Cancer and other Gynecologic Malignancies.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Conditions: Endometrioid Endometrial Cancer
International CDKL5 Clinical Research Network
Recruiting
Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments and cortical visual impairment. While capability for disease modifying therapies is accelerating, there is a critical barrier for clinical trial readiness that may result in failure of these therapies, not due to lack of efficacy but due to lack of validated outcome mea... Read More
Gender:
ALL
Ages:
Between 1 month and 100 years
Trial Updated:
12/05/2023
Locations: Baylor College of Medicine/ Texas Children's Hospital, Houston, Texas
Conditions: CDKL5, CDKL5 Deficiency Disorder, CDD