Texas is currently home to 4854 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
ROSE-Longitudinal Assessment With Neuroimaging
Recruiting
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: Houston Methodist, Houston, Texas
Conditions: Intracerebral Hemorrhage
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
Recruiting
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/10/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: Sarcoidosis, Pulmonary
An Enhanced Home-Based Telemedicine Program Using Remote Examination Devices for Children With Medical Complexity
Recruiting
The purpose of this study is to assess if the benefits for children with medical complexity (CMC) receiving comprehensive care (CC) in an enhanced medical home can be further improved by enhanced telemedicine program (ETM) provided during clinic hours using mobile devices to measure temperature\& oxygen saturation, auscultate the heart \& lungs, and view the skin, throat, \& tympanic membranes in the home.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
05/10/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Chronic Diseases in Children
The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.
Recruiting
The purpose of this study is to determine the effect of a dietary supplement rich in nitric oxide (NO) on nasal nitric oxide and fractional exhaled nitric oxide (FeNO),on ciliary beat frequency assessed by high-speed digital video microscopy and on lung function assessed by spirometry in normal patients and patients with Primary ciliary dyskinesia (PCD).
Gender:
ALL
Ages:
Between 4 years and 99 years
Trial Updated:
05/10/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Primary Ciliary Dyskinesia
COVID-19 Outcome Prediction Algorithm
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
Recruiting
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these genes, and determine genetic and environmental modifiers of H-TAD.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Aortic Aneurysm, Aortic Dissection, Aortic Diseases
Strawberry Candy Twists as an Alternative Screen for Gestational Diabetes: A Prospective Trial
Recruiting
The goal of this prospective study is to determine whether there is superiority of 10 Twizzlers to the 50 gram glucola beverage for screening for GDM in a population based study.
Gender:
FEMALE
Ages:
Between 18 years and 64 years
Trial Updated:
05/09/2023
Locations: Ben Taub General Hospital, Houston, Texas
Conditions: Gestational Diabetes Mellitus
Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR
Recruiting
To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-carotid)
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/08/2023
Locations: Baylor Scott and White Heart Hospital, Plano, Texas
Conditions: Iliac Disease, Aortic Valve Stenosis
Seaweed-derived Rhamnan Sulfate and Vascular Function
Recruiting
The primary aim of the proposed investigation is to examine the hypothesis that a relatively short period of rhamnan sulfate supplementation would improve key markers of vascular dysfunction in middle-aged and older adults with at least one risk factors for cardiovascular disease.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
05/08/2023
Locations: Cardiovascular Aging Research Lab at UT Austin, Austin, Texas
Conditions: Cardiovascular Diseases
Impact of Customized Respiratory Training on Cardiopulmonary Function in Parkison's Disease
Recruiting
People with PD have lower cardiopulmonary function than their age matched peers. This decline can further impair a person's ability to participate in exercise and daily activities. Furthermore, the limitations in cardiopulmonary function can have a severe impact on mortality. There is evidence indicating the positive changes IMT can have on cardiopulmonary function in people with PD. Through intensive daily exercise people with PD have shown improvements in maximum inspiratory pressure and maxi... Read More
Gender:
ALL
Ages:
Between 30 years and 99 years
Trial Updated:
05/08/2023
Locations: University of St. Augustine for Health Sciences, Austin, Texas
Conditions: Parkinson Disease
Affect Treatment for Depression and Anxiety
Recruiting
The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety. Target enrollment is 100 male and female participants with low positive affect and depression or anxiety and impaired functioning, between the ages of 18 and 65 years, who will be randomized to either Positive Aff... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2023
Locations: Southern Methodist University, Dallas, Texas
Conditions: Depression, Anxiety
Deposit Contracts to Increase Accessibility of a Contingency Management Intervention to Reduce Problematic Drinking
Recruiting
This study will examine the effects of an incentive-based intervention (for reducing alcohol use) that would be sustainable, easily accessible intervention using remote alcohol monitoring and deposit contracts, targeting individuals who would not be reached by more traditional forms of treatment due to barriers such as time constraints, attitudes, and stigma.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/03/2023
Locations: University Of North Texas, Denton, Texas
Conditions: Alcohol Abuse, Alcohol Intervention, Transdermal Alcohol Monitoring, Contingency Management, Deposit Contract