Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Can the Language Environment Analysis Start Program Improve Children's Readiness for School? LENA Program Evaluation
Recruiting
The objective of the project is to implement the LENA Start Program at the Alief The objective of the project is to implement the LENA Start Program at the Alief Independent School District in Houston, Texas. The purpose of the study is to learn how maternal expectations about language development influence the child's language development. Also, the study will evaluate how much the mothers believe can affect their child's language development. More specifically, the program implementation will... Read More
Gender:
ALL
Ages:
Between 16 months and 30 months
Trial Updated:
12/20/2022
Locations: Alief ISD, Houston, Texas
Conditions: Language Development
Procedural Discomfort Related to Number of Intradetrusor Botox Injections
Recruiting
Injection of intradetrusor OnabotulinumtoxinA (BTX-A) is a highly efficacious therapy with a reliable safety profile and demonstrable improvements in subjective and objective measures for overactive bladder (OAB) symptom control. This procedure can be performed in the office with an evidence-based standard dosing of 100 units for idiopathic OAB. This is a single-blinded, randomized control trial is to evaluate and optimize the technique for performing intradetrusor injections of BTX-A for idiopa... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/14/2022
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Overactive Bladder
GABA Biomarkers in Dravet Syndrome
Recruiting
This study will non-invasively obtain levels of GABA in the brain of children with SCN1A+DS and neurodeveloping children through evoked and induced cortical responses, correlate them with the BOLD responses, and with the levels of GABA in their blood.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
12/13/2022
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Dravet Syndrome
Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study
Recruiting
A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
11/01/2022
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Cervical Spine Fracture
Network Effects of Therapeutic Deep Brain Stimulation
Recruiting
The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2022
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Intractable Epilepsy
Safety and Effectiveness of the CustomFlex Artificial Iris Prosthesis for the Treatment of Iris Defects
Recruiting
The purpose of this study is to study the long term safety and effectiveness of an artificial iris prosthesis for the treatment of iris defects.
Gender:
ALL
Ages:
3 years and above
Trial Updated:
10/21/2022
Locations: Alkek Eye Center/ Baylor College of Medicine, Houston, Texas
Conditions: Full Aniridia, Partial Aniridia
CERENOVUS Neurothrombectomy Devices Registry
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: University of Texas Houston, Houston, Texas
Conditions: Cerebral Stroke
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
Recruiting
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted. Subjects will be randomly assigned to wear NaturalVue Sphere single vision contact lenses (SVCL) or NaturalVue Multifocal (NVMF) soft contact lenses for a total of three years.
Gender:
ALL
Ages:
Between 7 years and 13 years
Trial Updated:
10/03/2022
Locations: Bellaire Family Eye Care, Bellaire, Texas
Conditions: Myopia
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Recruiting
This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost ophthalmic solution, 0.01% of Amneal EU, Limited Reference Product - LUMIGAN® (bimatoprost ophthalmic solution) 0.01% of Allergan, Inc.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2022
Locations: Keystone Research, Austin, Texas
Conditions: Glaucoma, Open-Angle, Ocular Hypertension
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: William Beaumont Army Medical Center, El Paso, Texas
Conditions: Breast Cancer
Horizon Eagle Fatherhood Program
Recruiting
Horizon Outreach has developed the Horizon Eagle Fatherhood Program (HEFP). HEFP includes a program/services aspect, but also includes a rigorous evaluation component, featuring a randomized control trial (RCT) research design. The evaluation will determine the effect of the Horizon Eagle Fatherhood Program with fathers aged 18 and up in Houston, Texas. Specifically, the research is examining the effects of the program relative to: (1) improvement in healthy relationship and marriage skills, (2)... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/22/2022
Locations: Horizon Outreach, Houston, Texas
Conditions: Responsible Fatherhood Programming
A Study of FWD1509 in Adults With Non-Small Cell Lung Cancer
Recruiting
The purpose of this study is to characterize the safety and tolerability of FWD1509 MsOH in advanced NSCLC patients and establish the maximum tolerable dose (MTD), recommended phase 2 dose (RP2D) in advanced NSCLC patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/20/2022
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Carcinoma, Non-Small-Cell Lung