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Pain Clinical Trials
A listing of 122 Pain clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
61 - 72 of 122
There are currently 122 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Recruiting
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)
Recruiting
Management of neonatal pain and sedation often includes opioid therapy. A growing body of evidence suggests long-term harm associated with neonatal opioid exposure. Providing optimal sedation while neonates are undergoing therapeutic hypothermia (TH) may be beneficial but also presents therapeutic challenges. While there is evidence from animal models of brain injury and clinical trials in adults to support the safety and neuroprotective properties of dexmedetomidine (DMT), there are no publishe... Read More
Gender:
ALL
Ages:
24 hours and below
Trial Updated:
01/23/2025
Locations: Intermountain Medical Center, Murray, Utah +4 locations
Conditions: Hypoxic-Ischemic Encephalopathy, Pain
Meaning-Centered Pain Coping Skills Training for Cancer Pain
Recruiting
This study is a randomized controlled trial of a psychosocial pain management intervention called, Meaning-Centered Pain Coping Skills Training (MCPC). Patients with advanced solid tumor cancer and pain interference (N=210) will be randomized to MCPC or a standard care control condition. Patient-reported outcomes will be assessed at baseline and 8- and 12-week follow-ups. The risk and safety issues in this trial are low and limited to those common to a psychosocial intervention (e.g., loss of co... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: Duke Cancer Center, Durham, North Carolina
Conditions: Advanced Solid Tumor, Pain
Anesthetics and Analgesics in Children
Recruiting
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
01/21/2025
Locations: Lucile Packard Children's Hospital, Stanford, California +12 locations
Conditions: Anesthesia, Pain
Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults with Chronic Pain
Recruiting
Over one-quarter of American adults engage in hazardous drinking (i.e., a pattern of alcohol consumption that increases risk for harmful consequences), which is the third leading cause of preventable death in the U.S. Rates of hazardous drinking are significantly higher among individuals with (vs. without) chronic pain. Moreover, 20% of individuals prescribed opioids endorse concurrent alcohol and opioid use, which may interfere with chronic pain treatment and lead to dangerous/potentially fatal... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
01/20/2025
Locations: Syracuse University, Syracuse, New York
Conditions: Alcohol Drinking, Pain, Opioid Use, Feedback, Psychological
FDG PET/MR Imaging of Peripheral Pain Generators
Recruiting
The purpose of this research is to determine if a PET/MRI scan using FDG can accurately identify the source of chronic pain. Identifying the source of pain may help doctors treat chronic pain more effectively. Approximately 128 participants will be enrolled and can expect to be on study for up to 12 months.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/16/2025
Locations: UW School of Medicine and Public Health, Madison, Wisconsin
Conditions: Pain, Nociceptive Pain
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
Recruiting
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
01/09/2025
Locations: Antonia Oladipo, Hackensack, New Jersey
Conditions: Nausea, Pain
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
Recruiting
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments on cravings (primary outcome) in adults with an opioid use disorder. The investigators will also evaluate the effects of "assisted" rate cycling, voluntary rate cycling and I-STOP on secondary outcomes including depression, anxiety and sleep.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/20/2024
Locations: University of Colorado at Denver, Denver, Colorado +1 locations
Conditions: Opioid Use Disorder, Pain
Analgesic and Subjective Effects of Terpenes
Recruiting
The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
12/17/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Abuse, Drug
Low-Dose Ketamine Infusion During Burn Wound Care
Recruiting
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Regional One Health, Memphis, Tennessee
Conditions: Burn, Pain, Dissociation, Opioid
Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
Recruiting
Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, the investigators will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, decision-making, and activation of different neural substrates.
Gender:
ALL
Ages:
Between 21 years and 45 years
Trial Updated:
12/09/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Pain
Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia
Recruiting
The goal of this study is to compare the abuse potential of low-dose equianalgesic buccal buprenorphine to a commonly used full mu opioid receptor (MOR) agonist in a highly controlled experimental setting. This is a translational study in which healthy participants are phenotyped for psychosocial and Opioid-Use-Disorder-risk-related metrics. In a within-subjects crossover design, 60 participants will receive a standard postoperative oral oxycodone dose (10 mg), placebo, and 3 different doses of... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Analgesia, Abuse Opioids, Pain
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
Recruiting
The purpose of this study is to test whether yoga can reduce nerve pain caused by cancer treatment (chemotherapy-induced peripheral neuropathy, or CIPN). Participants will take one of three approaches:
* Yoga classes
* Educational sessions on the causes and impacts of CIPN, how yoga may help with CIPN, and how different therapies may help with CIPN
* Usual care with standard-of-care medications for CIPN
The researchers will compare how these different approaches affect participants' balance, t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts +7 locations
Conditions: Chemotherapy-Induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful, Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chronic Pain
61 - 72 of 122