There are currently 135 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
The Warmth, Anticipation, Sensation, Aversion, and Body-part Imaging Study
NCT04653064
Recruiting
This functional magnetic-resonance imaging study of the brain will feature a within-subject crossover design to investigate the effects of a placebo cream on painful thermal stimulation rendered upon eight body sites. The investigators aim to 1.) improve the understanding of how the brain represents thermal pain responses somatotopically (i.e., across different body-sites) 2.) to test these brain representations with and without the presence of a pain-targeted placebo intervention, and 3.) to ex... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/15/2024
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Pain
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Randomized Controlled Comparison of Pre-op TLIP Vs Intra-op TLIP
NCT06154980
Recruiting
Single-center, randomized study will enroll 50 subjects who are scheduled for 1-3 level posterior laminectomy \& fusion. Study participants who are eligible for the posterior lumbar laminectomy and fusion procedure will be scheduled and also consented as a part of the study. Participants will be stratified based on age and gender to ensure equal distribution.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: William Beaumont Hospital, Royal Oak, Michigan
Conditions: Pain, Spine Fusion
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M2VA Pain Care Pathway
NCT06526143
Recruiting
The goal of this 2-cohort, cluster randomized, type 2 hybrid trial is to test the effectiveness, cost-effectiveness and patient-level effects of an implementation facilitation strategy in helping M2VA case managers adopt a Military2VA Pain Care Pathway (M2VAPCP) intervention. The main questions it aims to answer are: Will adding implementation facilitation to training-as-usual for M2VAPCP result in a higher proportion of Veterans who receive M2VAPCP compared to training-as-usual alone? Will ad... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: VA Connecticut Healthcare System (VACHS), West Haven, Connecticut
Conditions: Pain, Substance Use, Opioid Misuse, Quality of Life
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Brainwave Activity Response on Common Physical Therapy Intervention
NCT04542707
Recruiting
This study is designed to evaluate the if there is a predictable patterns in brainwave activity and to see how this changes with external physical therapy interventions such as manipulation, soft tissue massage, and exercise.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/05/2024
Locations: Florida Gulf Coast University, Fort Myers, Florida
Conditions: Pain
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Post-Op Pain Control for Prophylactic Intramedullary Nailing.
NCT03823534
Recruiting
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because no fracture is present, these patients do not rely on inflammatory healing factors, allowing for post... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Saint Louis University, Saint Louis, Missouri
Conditions: Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use, Pain
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TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence.
NCT06369922
Recruiting
This will be a double-blind randomized control trial in women with stress urinary incontinence who are undergoing an outpatient transurethral bulking procedure for stress urinary incontinence. Subjects will be identified by the University of Rochester urologists and urogynecologists participating in the study who currently oversee stress incontinence care. Subjects will be randomized into two groups. One group will be undergoing the cystoscopy with transcutaneous electrical nerve stimulation (TE... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Pelvic Health and Continence Specialties, Rochester, New York
Conditions: Stress Incontinence Female, Urinary Incontinence, Urinary Incontinence,Stress, Pain, Pain Acute
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Effects of Dronabinol in Opioid Maintained Patients
NCT04025359
Recruiting
Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of opioid-related outcomes. Pain sensitivity will be measured using a technique called the (QST) quantitative sensory testing, which involves the administ... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/04/2024
Locations: VA Healthcare System, West Haven, Connecticut
Conditions: Pain
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Efficacy of Guided Imagery Therapy Mobile Application for Functional Abdominal Pain
NCT06653647
Recruiting
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies. This clinical trial aims to see how well pre-recorded guided imagery therapy sessions help children's abdominal pain when delivered via a mobile application (app) on a smartphone or tablet. Participants will complete a baseline abdominal pain and stooling diary to determine eligibility and... Read More
Gender:
ALL
Ages:
Between 7 years and 12 years
Trial Updated:
10/28/2024
Locations: Baylor College of Medicine / Texas Children's Hospital, Houston, Texas
Conditions: Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders, Functional Colonic Disease, Gastrointestinal Disease, Digestive System Diseases, Neurological Manifestations, Signs and Symptoms, Digestive, Pain, Abdominal Pain/ Discomfort
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A Phase 1 Dose Escalation Study of VX-973 in Healthy Participants
NCT06615570
Recruiting
The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of VX-973 in healthy participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
10/25/2024
Locations: ICON Salt Lake City, Salt Lake City, Utah
Conditions: Pain
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Vestibular Innovation in Pain
NCT06559839
Recruiting
The VIP trial will assess the effectiveness, tolerability, and durability of effect of vestibulocortical stimulation (VCS) - a safe \& cost-effective bedside technique - in treating pain, fatigue \& related symptoms using validated patient-reported outcomes. Data from this trial will be used to guide optimized treatment protocols in future randomized controlled trials and help inform the implementation of VCS into standard clinical practice.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
10/22/2024
Locations: Mount Sinai West, New York, New York
Conditions: Pain, Fatigue, Quality of Life
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Intravenous Gammaglobulin for Sickle Cell Pain Crises
NCT01757418
Recruiting
The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease. Funding Source: Food and Drug Administration (FDA), Office of Orphan Products Development (OOPD)
Gender:
ALL
Ages:
Between 6 years and 65 years
Trial Updated:
10/17/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Sickle Cell Disease, Pain
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Options for Pain Management Using Nonpharmacological Strategies
NCT05563792
Recruiting
The purpose of this study is to help Veterans learn about different ways they can manage chronic pain that do not involve medications. Veterans will work with a coach to explore the Veterans' values and goals and how different non-medication approaches may fit into these values and goals.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2024
Locations: Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis, Indiana
Conditions: Pain
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