There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP
NCT06154980
Recruiting
Single-center, randomized study will enroll 50 subjects who are scheduled for 1-3 level posterior laminectomy & fusion. Study participants who are eligible for the posterior lumbar laminectomy and fusion procedure will be scheduled and also consented as a part of the study. Participants will be stratified based on age and gender to ensure equal distribution.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: William Beaumont Hospital, Royal Oak, Michigan
Conditions: Pain, Spine Fusion
Register for Updates
RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Physicians Research Group, LLC, Phoenix, Arizona +110 locations
Conditions: Pain
Register for Updates
Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism
NCT04798469
Recruiting
The aim of this trial is to evaluate whether testosterone replacement results in greater improvement in pain perception, pain tolerance, sexual function, fatigue, and quality of life when compared with placebo in men with chronic back pain treated with opioids who have opioid-induced hypogonadism (low testosterone).
Gender:
Male
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Opioid Use, Pain, Hypogonadism, Male
Register for Updates
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
NCT06214923
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
06/05/2024
Locations: Luana Colloca, Baltimore, Maryland +1 locations
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Register for Updates
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
NCT05688410
Recruiting
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments on cravings (primary outcome) in adults with an opioid use disorder. The investigators will also evaluate the effects of "assisted" rate cycling, voluntary rate cycling and I-STOP on secondary outcomes including depression, anxiety and sleep.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/03/2024
Locations: University of Colorado at Denver, Denver, Colorado +1 locations
Conditions: Opioid Use Disorder, Pain
Register for Updates
Testing the Pain Clinical Practice Guideline
NCT05858996
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
06/01/2024
Locations: Communicare Ellicott City, Ellicott City, Maryland +2 locations
Conditions: Pain, Dementia
Register for Updates
Virtual Reality (VR) for Prone Pain Procedures
NCT05615675
Recruiting
The purpose of this study is to evaluate the effectiveness of virtual reality (VR) distraction in patients undergoing interventional pain procedures in the prone position. VR has been shown to improve patient experience during interventional pain procedures, however, many of these procedures are done in the prone position making VR a challenge. This study will evaluate the effect of a VR headset and support in patients undergoing prone interventional pain procedures compared to control.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: UC Davis Interventional Pain Clinic, Sacramento, California
Conditions: Virtual Reality, Anxiety, Pain
Register for Updates
Feasibility of a Mindfulness Intervention for Endometriosis Surgery
NCT06141720
Recruiting
Endometriosis is a common cause of pelvic pain in women which has been historically under-studied and under-diagnosed. The goal of this research is to pilot-test the feasibility and acceptability of a manualized, single-session brief mindfulness-based intervention (BMBI) among participants with endometriosis-related chronic pelvic pain (ECPP) who undergo surgical treatment, and gather preliminary data necessary for future studies assessing BMBI's impact on outcomes in surgically-treated ECPP. Th... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Penn State Health, Hershey, Pennsylvania
Conditions: Endometriosis, Pain, Mindfulness
Register for Updates
Clinical and Scientific Assessment of Pain and Painful Disorders
NCT02707029
Recruiting
Background: Researchers want to better understand pain by studying people with and without different kinds of pain. To do this, researchers will expose people to pleasant and unpleasant sensations. They will ask them questions about their pain. Researchers also want to see if these people are eligible for other research studies at the National Center for Complementary and Integrative Health. Objectives: To study the experience of pain. Also to find people eligible to join other NIH studies.... Read More
Gender:
All
Ages:
Between 12 years and 120 years
Trial Updated:
05/30/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Pain
Register for Updates
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment
NCT03258580
Recruiting
Background: People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective: To study if social and cultural factors lead to differences in pain experience and how pain is interpreted by other individuals. Eligibility: Healthy adults ages 18-60 Design: Participants will h... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/29/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Healthy Volunteers, Pain
Register for Updates
A Phase 1 Dose Escalation Study of Intravenous VX-993 in Healthy Adults
NCT06394167
Recruiting
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of intravenously administered VX-993 at different doses in healthy participants.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/28/2024
Locations: ICON Lenexa, Lenexa, Kansas
Conditions: Pain
Register for Updates
Brainwave Activity Response on Common Physical Therapy Intervention
NCT04542707
Recruiting
This study is designed to evaluate the if there is a predictable patterns in brainwave activity and to see how this changes with external physical therapy interventions such as manipulation, soft tissue massage, and exercise.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/27/2024
Locations: Florida Gulf Coast University, Fort Myers, Florida
Conditions: Pain
Register for Updates