There are currently 120 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Virtual Reality for Pain Management in Burn Patients
NCT04685486
Recruiting
This study is a randomized proof-of-concept study to assess the efficacy of Virtual Reality (VR) vs standard of care in 50 adult patients in the New York Presbyterian Burn Unit. The participants who are randomized to receive the virtual reality intervention will also receive opioids, which is the standard of care and is known to be effective. Participants will be randomly assigned to two groups. The first group will receive VR during their painful procedure (e.g., wound dressing changes, physica... Read More
Gender:
ALL
Ages:
8 years and above
Trial Updated:
07/30/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Pain
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Anesthetics and Analgesics in Children
NCT03427736
Recruiting
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
07/29/2025
Locations: Lucile Packard Children's Hospital, Stanford, California +12 locations
Conditions: Anesthesia, Pain
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Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment
NCT06032559
Recruiting
This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigators will also assess barriers and facilitators to integrating MORE into methadone treatment, and evaluate the impact of a sustainable train-the-trainer model on provider burden, intervention fidelity, intervention engagement, and outcomes. Participants will be assigned to a higher intensity MORE imple... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2025
Locations: Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey +1 locations
Conditions: Opioid Use, Pain
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Cannabis for Palliative Care in Cancer
NCT06266611
Recruiting
Many cancer patients suffer from pain, sleep, and mood problems and are using cannabis to relieve these symptoms. Cannabis may provide such relief but may also produce negative side effects including cognitive impairment, an especially problematic issue for cancer patients, indicating more research on cannabis use in the cancer context is required. In this endeavor, the present study seeks to compare the use of hemp-derived CBD (Cannabidiol) with and without THC (Delta-9-tetrahydrocannabinol) ve... Read More
Gender:
ALL
Ages:
25 years and above
Trial Updated:
07/29/2025
Locations: Anschutz Health Sciences Building, Aurora, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial
NCT06075797
Recruiting
The goal of this pilot randomized controlled trial is to test the feasibility of running a full scale randomized controlled trial that compares the effect of the PQ-ResPOND intervention versus usual care to improve recurrent pain in children, adolescents, and young adults with severe neurologic impairment. The main questions it aims to answer are: * Is the study feasible and acceptable for participants? * Does PQ-ResPOND have a potential to be effective? Participants will: * answer surveys (t... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
07/28/2025
Locations: University of Alabama, Birmingham, Birmingham, Alabama +3 locations
Conditions: Cerebral Palsy Infantile, Disabilities Multiple, Pain
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Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype
NCT05269628
Recruiting
The purpose of this research study is to compare the effects of cannabidiol (CBD), tetrahydrocannabinol (THC), or both, on sleep and pain in persons with multiple sclerosis (MS). Little is known about how CBD and/or THC may help sleep, reduce pain, or perhaps even treat pain through better sleep.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/23/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Multiple Sclerosis, Sleep, Pain
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Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits
NCT06387290
Recruiting
The primary aim of this implementation-effectiveness trial is to examine the effectiveness of Mindfulness-Oriented Recovery Enhancement (MORE) and patient-centered chronic pain management visits in primary care as interventions to reduce chronic pain, improve quality of life, and reduce opioid-related harms among chronic pain patients on long-term opioid therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: UCSD Health, La Jolla, California +2 locations
Conditions: Chronic Pain, Prescription Opioid Misuse, Substance-Related Disorders, Pain, Narcotic-Related Disorders, Chemically-Induced Disorders, Mental Disorders, Opioid-Related Disorders, Neurologic Manifestations
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Music Use in Parturients Admitted to Labor & Delivery
NCT06969105
Recruiting
The goal of this clinical trial is to learn if music use affects anxiety or pain levels in parturients admitted to labor and delivery. It will also learn about the effect of music use on patient satisfaction. The main questions it aims to answer are: Does music use affect anxiety levels in parturients admitted to labor and delivery? Does music use affect pain levels in parturients admitted to labor and delivery? Does music use affect patient satisfaction in parturients admitted to labor and del... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/16/2025
Locations: Tufts Medical Center, Boston, Massachusetts
Conditions: Anxiety, Pain, Patient Satisfaction
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PAINED: Project Addressing INequities in the Emergency Department
NCT05488080
Recruiting
Racial and ethnic inequities in health care quality have been described across a broad range of clinical settings, patient populations, and outcomes. Our overarching goal is to eradicate health care inequities through evidence-based interventions. The objectives of this proposal are to develop and test the impact of two interventions on overcoming clinician implicit bias and mitigating inequities in the management of pain among children seeking care in the emergency department for the treatment... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
07/14/2025
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Pain, Appendicitis, Bias, Racial, Fractures, Bone
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High Potency Cannabis: Acute and Protracted Effects
NCT06859723
Recruiting
The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
07/14/2025
Locations: UCLA Center for Cannabis and Cannabinoids, Los Angeles, California
Conditions: Abuse Cannabis, Pain, Pharmacokinetics
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Augmented Reality For MRI-Guided Interventions
NCT06224933
Recruiting
The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
07/09/2025
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Infections, Pain, Diagnosis
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ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery
NCT06091241
Recruiting
Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants. Deep Inferior Epigastric Perforator (DIEP) flaps are the gold standard for autologous breast reconstruction . Effective pain control following surgery is imperative and ultrasound-guided bilateral transversus abdominis plane blocks (TAPs) with the infiltration of local anesthetics, such a bu... Read More
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
07/07/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pain
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