There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Evaluation of Post-PACU Pain Management in Pediatric Surgery
NCT02352116
Recruiting
This study aims to assess the differences in overall pain severity, pain management, and satisfaction during recovery period between two groups of children who either receive or do not receive additional education related to expectation and management of postoperative pain.
Gender:
All
Ages:
Between 1 year and 6 years
Trial Updated:
03/21/2024
Locations: Columbia University, New York, New York
Conditions: Pain
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Transcutaneous Electrical Nerve Stimulation (TENS) for IUD Insertion Pain
NCT06245655
Recruiting
This study is a double-blind, randomized, placebo-controlled trial to evaluate the use of high frequency TENS for pain control during IUD insertion. Transcutaneous electrical nerve stimulation (TENS) is a relatively low-cost, low-risk, non-pharmacologic intervention for pain management. Previous studies have found that TENS reduces pain associated with other outpatient gynecological procedures. Participants will be randomized in a 1:1 ratio to either active treatment or placebo (placebo TENS) an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Mount Sinai Beth Israel, New York, New York +3 locations
Conditions: Pain
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Transcutaneous Electrical Nerve Stimulation (TENS) for Chemotherapy Induced Peripheral Neuropathy (CIPN)
NCT06324344
Recruiting
The purpose of this pilot study is to examine the acceptability and proof of concept effectiveness of a wireless Transcutaneous Electrical Nerve Stimulation (TENS) technology to address Chemotherapy Induced Peripheral Neuropathy (CIPN). Participants, who satisfy the inclusion and exclusion criteria and sign the informed consent form will be randomly assigned with ratio of 1:1 into two groups. The patients and clinicans will be blinded for group allocation. One group will utilize TENS high-dose d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathy
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Sex, Hormones and Identity Affect Nociceptive Expression
NCT05787470
Recruiting
The Investigators have recently published on differences in pain sensitivity measures between cis and trans individuals in the local area. The investigators observed the anticipated differences in pain sensitivity between CM and CW (CW > CM), but found that the TW were phenotypically similar to CW in all measures. However, the investigators did not assess hormone level, nor did the investigators recruit TM participants. Here, with the assistance of two local community group stakeholders the inve... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/13/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pain, Gender Identity
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Transdiagnostic Cognitive Biomarkers
NCT04864080
Recruiting
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depres... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Pain, Depression
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The Role of Virtual Reality During Regional Anesthesia
NCT04163809
Recruiting
In this study, we will analyze the role of virtual reality in acute pain and anxiety management for regional anesthesia in pre-operative patients at Cedars-Sinai Medical Center.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/12/2024
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Anxiety, Pain
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The Warmth, Anticipation, Sensation, Aversion, and Body-part Imaging Study
NCT04653064
Recruiting
This functional magnetic-resonance imaging study of the brain will feature a within-subject crossover design to investigate the effects of a placebo cream on painful thermal stimulation rendered upon eight body sites. The investigators aim to 1.) improve the understanding of how the brain represents thermal pain responses somatotopically (i.e., across different body-sites) 2.) to test these brain representations with and without the presence of a pain-targeted placebo intervention, and 3.) to ex... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Pain
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Association Between Body Composition and Pain in Spinal Cord Injury
NCT05459207
Recruiting
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/29/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Pain, Inflammatory Response
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Chronic Pain in Rheumatoid Arthritis
NCT05038553
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of Colorado, Denver, Colorado +4 locations
Conditions: Arthritis, Rheumatoid, Pain
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Exparel vs. ACB With Bupivacaine for ACL Reconstruction
NCT06274008
Recruiting
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young athletes. The purpose of the current study is to determine if extended-release Bupivacaine Liposome Injectable Suspension (Exparel) is effective in decreasing at home narcotic consumption compared to standard Bupivacaine Adductor Canal Block f... Read More
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
02/21/2024
Locations: CHOC Children's Hospital, Orange, California
Conditions: ACL Tear, Opioid Misuse, Pain, Anxiety
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Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction
NCT06241742
Recruiting
The goal of this clinical trial is to test the ability of HT-6184 to decrease inflammation and pain in patients after third molar removal. The main question it aims to answer are: Does HT-6184 decrease inflammation in patients after third molar removal? Does HT-6184 decrease pain in patients after third molar removal? Participants will be asked to do the following during the clinical trial: Take a single oral dose of HT-6184 or placebo Allow a oral surgeon remove their third molar teeth Bloo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: CenExel JBR, Murray, Utah
Conditions: Pain
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Training in Evidence-based Treatments in Psycho-Oncology
NCT05674357
Recruiting
The goal of this research study is to train psychotherapists to administer individualized evidence-based psychotherapies in a cancer care setting to participants with elevated levels of distress due to their illness and/or treatment. The intervention will mirror clinical care in psycho-oncology in which the therapist, collaboratively with their supervisor, will choose specific components of the following evidence-based treatments to administer based on the clinical presentation of the patient a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Distress, Emotional, Depression, Anxiety, Fatigue, Pain, Insomnia
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