There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Recruiting
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain relief and functional improvement in participants with PLP/RLP after contralateral limb sciatic nerve block. Also, contribute to the basic science understanding of the crossed-withdraw reflex by demonstrating a known animal model phenomenon in human participants. Hypothesis: Contralateral limb sciatic nerve ane... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2023
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Pain, Amputation
Measuring Analgesic Interventions
Recruiting
It is generally recognized that pain assessment and management especially in newborns, children and other nonverbal populations is an unmet need. According to the American Medical Association, "the pediatric population is at risk of inadequate pain management, with age-related factors affecting pain management in children. Children are often given minimal or no analgesia for procedures that would routinely be treated aggressively in adults. Although much is now known about pain management in chi... Read More
Gender:
All
Ages:
Between 7 years and 21 years
Trial Updated:
01/31/2023
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Pain
A Phase 1, Randomized, Placebo-Controlled Safety and Tolerability Study Of Intravenous SBS-1000 in Healthy Adults
Recruiting
This study will be a single-center, double-blind, randomized placebo-controlled, adaptive, single ascending dose study.
Gender:
All
Ages:
Between 18 years and 59 years
Trial Updated:
01/31/2023
Locations: Altasciences Clinical Kansas, Overland Park, Kansas
Conditions: Pain, Acute Pain
AIMS Medical Outcomes Study
Recruiting
This epidemiologic research is being conducted as an observational prospective case series outcomes study of the use of advanced integrative specialty medical care and its effect on adult and pediatric patients with chronic or serious illnesses or mental health disorders.
Gender:
All
Ages:
All
Trial Updated:
01/30/2023
Locations: AIMS Institute, Seattle, Washington
Conditions: Mental Health Issue, PTSD, Pain, Chronic Pain, Chronic Disease
Pregabalin vs. Gabapentin on Reducing Opioid Usage
Recruiting
This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: Charleston Area Medical Center"s Level 1 Trauma Center, Charleston, West Virginia
Conditions: Analgesics, Gabapentin, Injuries, Narcotics, Pain, Trauma
STIMFIX Trail Lead Anchor System for Dorsal Column Stimulator Trail Leads (SECURE Study)
Recruiting
This project will investigate the efficacy of a Stimfix Trail lead anchor system (StimfixTM) in patients undergoing dorsal column stimulator trial. In dorsal column stimulator trails, two leads are placed in the epidural space and various frequencies, pulse widths, and amplitudes are run to reduce pain perception. This therapy has been in use for the last 70 years and today there are about 100,000 implants done annually for various pain indications. The process of obtaining the therapy requires... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: Lake side spine & pain, Lake Havasu City, Arizona +2 locations
Conditions: Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Recruiting
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies. To date, experiencing a painful stimulus has been known to disrupt motor activity in an attempt to minimize injury. However, physical activity, even when it increases ongoing pain initially, has been shown to significantly reduce pain symptoms eventually through neuromodulation. In both acute and chronic pain cohorts, exercise protocols and neuromodulatio... Read More
Gender:
All
Ages:
Between 10 years and 24 years
Trial Updated:
05/06/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Pain, Chronic Widespread Pain, Fibromyalgia
Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
Recruiting
This two arm, patient blinded, randomized, post market clinical trial in a single orthopedic hospital will determine whether there is improved pain management and decreased length of stay when comparing standard of care pain management with and without sufentanil.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
03/29/2022
Locations: The CORE Institute Specialty Hospital, Phoenix, Arizona
Conditions: Pain
Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation
Recruiting
The study's objective is to assess whether CAM methods are feasible and beneficial in the WSRH setting; to assess stress (using the Perceived Stress Scale-14 and using BioSquares™), anxiety (using the Generalized Anxiety Disorder-7 scale), depression (using the Patient Health Questionnaire-9 scale), pain (using the Wong-Baker FACES scale), and vital signs using a multidisciplinary complementary approach with Heartfulness Meditation, Conscious Breathing, and Emotional Freedom Technique - the CAM... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/05/2021
Locations: Wellspan Surgery and Rehabilitation Hospital, York, Pennsylvania
Conditions: Anxiety, Depression, Stress, Pain, Heart Rate, Blood Pressure
Effects of Aromatherapy on Patient Satisfaction With Surgical Abortion at Less Than 10 Weeks Gestation
Recruiting
The investigators propose a single-site, double-blinded, placebo-controlled clinical trial of lavender aromatherapy versus placebo for patient satisfaction in adult women having a surgical abortion before 10 weeks and 0 days gestation. The investigators will evaluate whether lavender aromatherapy is an effective adjunct therapy for patient satisfaction during first trimester surgical abortion. The investigators will measure satisfaction using the Iowa Satisfaction with Anesthesia Scale (ISAS). T... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
08/17/2021
Locations: Comprehensive Women's Health Center, Denver, Colorado
Conditions: Surgical Abortion, Patient Satisfaction, Anesthesia, Pain
Comparison of Quadratus Lumborum Block Types
Recruiting
This study will compare the quality of analgesia and reduction of opioid use, between standard of care and two groups of local anesthetic blocks in different location in the quadratus lumborum plane, for postoperative pain control after lumbar spinal fusion and if it reduces opioid consumption.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
03/18/2021
Locations: UMASS Memorial Medical Center, Worcester, Massachusetts
Conditions: Pain, Opioid Use, Lumbar Disc Herniation
Optimizing Pain Control in Transurethral Resection of the Prostate
Recruiting
The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/25/2019
Locations: Virginia Mason Medical Center, Seattle, Washington
Conditions: Pain, BPH With Urinary Obstruction, BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms