Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals
NCT05303415
Recruiting
Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations. Participants will receive MRI and CT imaging. Participants receive low-intensity focused ultrasound (LIFU) to temporarily change brain activity. Participants then receive fMRI scans to measure changes in both resting and heat evoked brain signaling using a quantitative sensory testing device. Heart rate, blo... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/29/2023
Locations: Fralin Biomedical Research Institute, Roanoke, Virginia
Conditions: Pain
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Decreasing Long-term Opioid Use in Cancer Survivors
NCT05067556
Recruiting
This is a feasibility pilot trial assessing a behavioral intervention for chronic pain among disease-free cancer survivors to decrease long-term opioid dependence.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/08/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Pain, Chronic Pain, Cancer Pain, Survivorship
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A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome
NCT05408741
Recruiting
To learn if using guided imagery and deep breathing techniques can help with pain management in patients who have post-mastectomy pain syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Pain Syndrome, Pain, Symptom Management
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Virtual Reality (VR) for Prone Pain Procedures
NCT05615675
Recruiting
The purpose of this study is to evaluate the effectiveness of virtual reality (VR) distraction in patients undergoing interventional pain procedures in the prone position. VR has been shown to improve patient experience during interventional pain procedures, however, many of these procedures are done in the prone position making VR a challenge. This study will evaluate the effect of a VR headset and support in patients undergoing prone interventional pain procedures compared to control.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: UC Davis Interventional Pain Clinic, Sacramento, California
Conditions: Virtual Reality, Anxiety, Pain
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Regional Blocks for Lateral Condyle Fractures
NCT03796572
Recruiting
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning. Patients will be randomized into one of two groups. Group 1 will receive an infraclavicular nerve block to the affected extremity by a fellowship trained pediatric anesthesiologist prior to surgery. Group 2 will undergo the Orthopaedic Institute of Children's (OIC) standard preoperative protocol. Post-operativ... Read More
Gender:
All
Ages:
Between 4 years and 12 years
Trial Updated:
11/22/2023
Locations: Orthopaedic Institute for Children, Los Angeles, California
Conditions: Fractures, Closed, Humeral Fractures, Pain
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The Warmth, Anticipation, Sensation, Aversion, and Body-part Imaging Study
NCT04653064
Recruiting
This functional magnetic-resonance imaging study of the brain will feature a within-subject crossover design to investigate the effects of a placebo cream on painful thermal stimulation rendered upon eight body sites. The investigators aim to 1.) improve the understanding of how the brain represents thermal pain responses somatotopically (i.e., across different body-sites) 2.) to test these brain representations with and without the presence of a pain-targeted placebo intervention, and 3.) to ex... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Pain
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Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain
NCT04592978
Recruiting
Over one-quarter of American adults engage in hazardous drinking (i.e., a pattern of alcohol consumption that increases risk for harmful consequences), which is the third leading cause of preventable death in the U.S. Rates of hazardous drinking are significantly higher among individuals with (vs. without) chronic pain. Moreover, 20% of individuals prescribed opioids endorse concurrent alcohol and opioid use, which may interfere with chronic pain treatment and lead to dangerous/potentially fatal... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
11/20/2023
Locations: Syracuse University, Syracuse, New York
Conditions: Alcohol Drinking, Pain, Opioid Use, Feedback, Psychological
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Virtual Reality at End-of-life
NCT06149429
Recruiting
The purpose of this research is to determine the effect that repeated, personalized virtual reality experiences have on symptom severity, comparing self-reported symptom severity both pre and post each session, and overtime across sessions. We will also determine if this intervention results in a high rating of presence in VR, and if presence is related to the magnitude of the change in symptoms.
Gender:
All
Ages:
All
Trial Updated:
11/20/2023
Locations: Hospice and Palliative Care Buffalo, Cheektowaga, New York
Conditions: End of Life, Pain, Nausea, Fatigue, Well-Being, Psychological, Depression, Dyspnea, Appetite Loss, Anxiety
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RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Physicians Research Group, LLC, Phoenix, Arizona +110 locations
Conditions: Pain
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Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
NCT04827992
Recruiting
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain intensity and interference when added to a 24-week behavioral intervention (POTS).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/16/2023
Locations: Maine Medical Center, Portland, Maine +2 locations
Conditions: Opioid Use, Pain, Marijuana Use
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Evaluation of Objective Pain Measurement Device
NCT03975660
Recruiting
This study will attempt to objectively measure pain with an experimental device. The investigators will apply the device to measure patients "pain" due to uterine contractions during routine clinical care to correlate patients verbal pain ratings and analgesia requirements to that measured by the device. A brain oxygenation device, Edwards Foresight, will be used to concurrently to monitor brain oxygenation and hemodynamics, so the relationship between the CereVu ROPA device objective measure of... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
11/15/2023
Locations: Stanford University, Stanford, California
Conditions: Pain, Analgesia, Labor Pain
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PainChek® US Validation Nursing Home Study
NCT06049732
Recruiting
Pain is common amongst people living with dementia. However, as people's dementia worsens their ability to self-report pain diminishes because of limitations in their cognition and communication abilities. As a result pain in people with moderate to severe dementia often goes under-recognised and undertreated. PainChek® is a technology-enabled, observational pain assessment tool, in the form of a mobile application designed specifically to assist healthcare professionals and professional caregi... Read More
Gender:
All
Ages:
All
Trial Updated:
11/14/2023
Locations: NewAldaya Lifescapes, Cedar Falls, Iowa +3 locations
Conditions: Dementia, Pain
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