There are currently 127 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Pain After Buffered Vs Non Buffered Articaine
NCT06538233
Recruiting
Pain after buffered versus non buffered articaine.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/31/2024
Locations: Clevland Dental Institute, Cleveland, Ohio
Conditions: Pain
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Postoperative Pain After Activation of Irrigant
NCT06528574
Recruiting
The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation techniques, negative pressure irrigation technique and traditional irrigation techniques. PICOTS Question: Does the new Dent's iVac irrigation protocol has an effect on reduction of postoperative pain By enlisting at least 84 suitable individuals who are undergoing t... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/26/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Pain
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Pain Perception Measurement by EEG and NRS
NCT06510244
Recruiting
Observational study at CDI Cleveland Dental Institute. Investigators will assess the pain perception in one group of patients using two non-invasive methods. First, a numerical rate scale (NRS) and second, a brain wave EEG.
Gender:
ALL
Ages:
Between 20 years and 60 years
Trial Updated:
07/19/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Pain, Electroencephalography, Toothache
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Testing the Pain Clinical Practice Guideline
NCT05858996
Recruiting
There are evidence based processes for assessment and management of pain using pharmacologic and nonpharmacological approaches. These were reviewed and included within the Pain Management Clinical Practice Guideline (Pain Management CPG) recently developed by AMDA: The Society for Post-Acute and Long-Term Care Medicine. There are, however, many challenges to translating the use of Clinical Practice Guidelines into clinical settings. To overcome these challenges we developed and previously tested... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/23/2025
Locations: Future Care Coldspring, Baltimore, Maryland +6 locations
Conditions: Pain, Dementia
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Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
NCT06962306
Recruiting
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
Gender:
ALL
Ages:
Between 6 months and 4 years
Trial Updated:
05/23/2025
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
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Effects of Dronabinol in Opioid Maintained Patients
NCT04025359
Recruiting
Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of opioid-related outcomes. Pain sensitivity will be measured using a technique called the (QST) quantitative sensory testing, which involves the administ... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/22/2025
Locations: VA Healthcare System, West Haven, Connecticut
Conditions: Pain
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A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
NCT05081596
Recruiting
The purpose of the study is to examine the effect of Problem Adaptation Therapy for Pain (PATH-Pain) on cognitive functioning, depression and pain-related disability in 100 older adults with cognitive impairment, chronic pain, and depression. The study will test if PATH-Pain has better cognitive, affective, and functional outcomes than Attention Control Usual Care.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/20/2025
Locations: Weill Cornell Medicine, White Plains, New York
Conditions: Depression, Pain, Cognitive Impairment
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Integrating Pain-CBT Into an mHealth Analgesic Support Intervention for Patients With Chronic Pain From Advanced Cancers
NCT06722014
Recruiting
Smartphone Technology to Alleviate Malignant Pain (STAMP) + Cognitive Behavioral Therapy for Pain (STAMP+CBT) The purpose of the study is to develop and refine the mHealth pain-CBT app intervention and carry out a randomized pilot to test the novel mHealth (Mobile health technology) intervention, which harmonizes psychological and pharmacological support for advanced cancer pain. The name of the study smartphone application involved in this study is: -STAMP+CBT
Gender:
ALL
Ages:
22 years and above
Trial Updated:
05/14/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Pain, Pain Syndrome, Advanced Cancer
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Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy
NCT06842888
Recruiting
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb. This study will use two parallel groups: (1) receiving conventional mirror therapy as a part of the standard of care as conducted by the participant's clinical care team and (2) receiving mirror therapy with the Miraπ device as conducted by study personnel with the oversight of the participant's clinical care team.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Rehabilitation and Wellness Center at the Milford Campus of Bridgeport Hospital, Milford, Connecticut
Conditions: Stroke, Pain, Impaired Motor Function
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Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
NCT06374238
Recruiting
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support in... Read More
Gender:
ALL
Ages:
Between 16 years and 30 years
Trial Updated:
05/13/2025
Locations: Connecticut Children's Medical Center, Hartford, Connecticut +2 locations
Conditions: Pain, Sickle Cell Disease
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Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
NCT04994249
Recruiting
To identify diagnostic and prognostic biomarker signatures of recovery versus having persisting high-impact chronic pain and functional disability in adults with Chronic Musculoskeletal Pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/12/2025
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Musculoskeletal Pain, Pain, Pain, Chronic, Joint Pain
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The Role of Virtual Reality During Regional Anesthesia
NCT04163809
Recruiting
In this study, we will analyze the role of virtual reality in acute pain and anxiety management for regional anesthesia in pre-operative patients at Cedars-Sinai Medical Center.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/12/2025
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Anxiety, Pain
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