There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
NCT04269239
Recruiting
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several ph... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
01/10/2024
Locations: University of Texas Medical Branch, Galveston, Texas +2 locations
Conditions: Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
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Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors
NCT05869604
Recruiting
There are close to 700,000 survivors of adolescent and young adult (AYA) cancer (aged 15 to 39 at diagnosis) in the US. Survivorship for AYAs is often complicated by long-term and late-effects. Cardiovascular disease (CVD), in particular, is a leading cause of death for cancer survivors and is a growing public health concern for survivors diagnosed as AYAs. Risk of CVD may be associated with treatment exposures and may be potentiated by weight gain and poor health behaviors. Healthy eating and p... Read More
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
01/08/2024
Locations: Duke University, Durham, North Carolina
Conditions: Cancer, Cardiovascular Diseases, Weight Management, Pain, Fatigue, Distress, Emotional, Physical Inactivity
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Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
NCT05819619
Recruiting
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
01/05/2024
Locations: Antonia Oladipo, Hackensack, New Jersey
Conditions: Nausea, Pain
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Heating Pad for in Office Cystoscopy and Urodynamic Testing
NCT05981794
Recruiting
Patient frequently report experiencing discomfort associated with cystoscopy or urodynamic studies (UDS), and a small percentage of patients refuse these important procedures due to discomfort or fear of discomfort. Heating pads are an inexpensive and low-risk way to reduce patient discomfort during these procedures, which to our knowledge has not been investigated in the United States.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Anxiety, Pain, Distress, Emotional
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Oklahoma Study of Native American Pain Risk III: Stress and Resilience
NCT05723081
Recruiting
The goal of this observational study is to learn about the relationship between environmental structural racism and discrimination and chronic pain risk in Native American adults. The main questions it aims to answer are: How does environmental structural racism and discrimination affect chronic pain-promoting mechanisms in Native Americans? What psychosocial factors buffer the negative effects of environmental structural racism and discrimination on chronic pain-promoting mechanisms?
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: University of Oklahoma - Schusterman Center, Tulsa, Oklahoma
Conditions: Discrimination, Racial, Stress Physiology, Pain
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Can Medical Cannabis Affect Opioid Use?
NCT06206252
Recruiting
The goal of this observational study is to learn how medical cannabis (MC) affects pain and the use of opioid pain medications. Participants who have chronic pain and use prescribed opioid pain medication will opt-in to using MC or not for the 3-month study. Participants who are certified in Pennsylvania will purchase specific medical cannabis products at a reduced cost from a partnering medical cannabis dispensary monthly. All participants will complete baseline, daily, and monthly assessments... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Conditions: Chronic Pain, Pain
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Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers
NCT06186960
Recruiting
Background: Nature-based virtual reality (VR) and other outdoor experiences in head-mounted displays (HMDs) offer powerful, non-pharmacological tools for hospice teams to help patients undergoing end-of-life (EOL) transitions. However, the psychological distress of the patient-caregiver dyad is interconnected and highlights the interdependence and responsiveness to distress as a unit. Hospice care services and healthcare need strategies to help patients and informal caregivers with EOL transitio... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Cottingham Hospice House, Seneca, South Carolina
Conditions: Hospice, End of Life, Palliative Care, Pain, Anxiety, Fear of Death
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Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
NCT04218409
Recruiting
Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, the investigators will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, decision-making, and activation of different neural substrates.
Gender:
All
Ages:
Between 21 years and 45 years
Trial Updated:
12/07/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Pain
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Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype
NCT05269628
Recruiting
The purpose of this research study is to compare the effects of cannabidiol (CBD), tetrahydrocannabinol (THC), or both, on sleep and pain in persons with multiple sclerosis (MS). Little is known about how CBD and/or THC may help sleep, reduce pain, or perhaps even treat pain through better sleep.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/07/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Multiple Sclerosis, Sleep, Pain
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A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain
NCT05838755
Recruiting
This is a multicenter randomized, double-blind, placebo-controlled phase 2 study to evaluate efficacy, safety, tolerability, pharmacokinetics, and target engagement of GSK3858279 in adult participants with chronic Diabetic Peripheral Neuropathic Pain (DPNP). The primary objective of the study is to assess the efficacy of GSK3858279 in participants with DPNP who have been unable to sufficiently manage their pain.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
12/05/2023
Locations: GSK Investigational Site, Anniston, Alabama +82 locations
Conditions: Pain
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Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience
NCT05074485
Recruiting
The first objective of the study is to evaluate whether a novel bio-signature (derived from a wide range of pro- and anti-nociceptive IL-1 family cytokine activity) will predict pain experienced and also release of underlying endogenous opioid neurotransmitters during an experimental nociceptive pain challenge, which will be performed while simultaneously quantifying mu-opioid receptor activity in the brain via [11C]-carfentanil PET neuroimaging in healthy subjects. Another objective is to evalu... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
12/01/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Pain
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Reliability of Pupil Response to Acute Pain
NCT02628314
Recruiting
The purpose of this research study is to test whether researchers can reliably measure the response pupils have when an acute painful stimulus is experienced. Changes in the size of the pupil of the eye can be an indicator of brain activity in a region of the brain that is important for feeling pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
12/01/2023
Locations: Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Conditions: Pain, Osteoarthritis
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