There are currently 140 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Pain After Buffered Vs Non Buffered Articaine
Recruiting
Pain after buffered versus non buffered articaine.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/31/2024
Locations: Clevland Dental Institute, Cleveland, Ohio
Conditions: Pain
Postoperative Pain After Activation of Irrigant
Recruiting
The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation techniques, negative pressure irrigation technique and traditional irrigation techniques. PICOTS Question: Does the new Dent's iVac irrigation protocol has an effect on reduction of postoperative pain By enlisting at least 84 suitable individuals who are undergoing t... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/26/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Pain
Pain Perception Measurement by EEG and NRS
Recruiting
Observational study at CDI Cleveland Dental Institute. Investigators will assess the pain perception in one group of patients using two non-invasive methods. First, a numerical rate scale (NRS) and second, a brain wave EEG.
Gender:
ALL
Ages:
Between 20 years and 60 years
Trial Updated:
07/19/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Pain, Electroencephalography, Toothache
Superficial Cervical Plexus Block for IJCL Pain Management
Recruiting
This is a prospective randomized trial evaluating the effect of SCPB on reported patient pain following IJCL placement as compared to local infiltrate.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/10/2024
Locations: Cleveland Clinic Akron General, Akron, Ohio
Conditions: Superficial Cervical Plexus Block, Pain
Stress and Pain in People Living With HIV
Recruiting
This is a basic human experimental study utilizing 4 groups of individuals with and without HIV and complex morbidities of cannabis use disorder and major depression who will participate in 2 sessions of the Yale Pain Stress Task (YPST) and follow-up phase to assess drug use and mood symptoms.
Gender:
ALL
Ages:
Between 18 years and 68 years
Trial Updated:
02/19/2025
Locations: The Yale Stress Center, New Haven, Connecticut
Conditions: HIV, Depression, Cannabis Use Disorder, Stress, Pain
Development of STEPPT
Recruiting
This 6-month pilot study aims to assess the feasibility, acceptability, and estimate effect sizes of the pilot STEPPT intervention for addressing ethnic disparities in physical therapy referrals and adherence between Hispanic and Non-Hispanic White patients with spine pain. Feasibility and acceptability will be assessed based on the extent to which the pilot clinic implements all components of the intervention appropriately, feedback from clinic staff during implementation of the intervention, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Family Health Centers of San Diego, San Diego, California
Conditions: Pain, Back Pain, Low Back Pain, Chronic Pain, Neck Pain
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment
Recruiting
This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigators will also assess barriers and facilitators to integrating MORE into methadone treatment, and evaluate the impact of a sustainable train-the-trainer model on provider burden, intervention fidelity, intervention engagement, and outcomes. Participants will be assigned to a higher intensity MORE imple... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey +1 locations
Conditions: Opioid Use, Pain
Clinical and Scientific Assessment of Pain and Painful Disorders
Recruiting
Background: Researchers want to better understand pain by studying people with and without different kinds of pain. To do this, researchers will expose people to pleasant and unpleasant sensations. They will ask them questions about their pain. Researchers also want to see if these people are eligible for other research studies at the National Center for Complementary and Integrative Health. Objectives: To study the experience of pain. Also to find people eligible to join other NIH studies.... Read More
Gender:
ALL
Ages:
Between 12 years and 120 years
Trial Updated:
02/15/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Pain
Neural and Psychological Mechanisms of Pain Perception
Recruiting
Background: - Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, not just pain. Researchers want to understand how different factors influence pain. They want to test what happens when people expect different levels of pain and receive treatments that can modify pain. They want to see if these factors influence decisions about pain and how the body responds to it. They also want to compare pain with resp... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
02/13/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Pain, Normal Physiology, Healthy Volunteers
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment
Recruiting
Background: People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective: To study if social and cultural factors lead to differences in pain experience and how pain is interpreted by other individuals. Eligibility: Healthy adults ages 18-60 Design: Participants will h... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
02/13/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Healthy Volunteers, Pain
Can Medical Cannabis Affect Opioid Use?
Recruiting
The goal of this observational study is to learn how medical cannabis (MC) affects pain and the use of opioid pain medications. Participants who have chronic pain and use prescribed opioid pain medication will opt-in to using MC or not for the 3-month study. Participants who are certified in Pennsylvania will purchase specific medical cannabis products at a reduced cost from a partnering medical cannabis dispensary monthly. All participants will complete baseline, daily, and monthly assessments... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Conditions: Chronic Pain, Pain
MBCT-T for Preoperative Pain Catastrophizing and Pain Outcomes After Spine Surgery
Recruiting
This is a two phase study. In phase 1, a focus group (N=5) will be conducted to adapt MBCT-T for use in the study population. In phase 2, a single-arm trial will be conducted examining four, weekly sessions of preoperative MBCT-T in subjects with high pain catastrophizing scheduled for spine surgery (N=20). Subjects will then be followed for two weeks postoperatively.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/11/2025
Locations: NYU Langone Health, Brooklyn, New York +1 locations
Conditions: Pain