There are currently 127 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA
NCT05468398
Recruiting
The study team aims to investigate whether implementing virtual reality therapy (VRT) during Genicular nerve radiofrequency ablation (GNRFA) procedure will provide better alleviation of procedural pain and augmented satisfaction for patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: UC Irvine Gottschalk Medical Plaza, Irvine, California
Conditions: Pain, Patient Satisfaction
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Exparel vs. ACB With Bupivacaine for ACL Reconstruction
NCT06274008
Recruiting
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young athletes. The purpose of the current study is to determine if extended-release Bupivacaine Liposome Injectable Suspension (Exparel) is effective in decreasing at home narcotic consumption compared to standard Bupivacaine Adductor Canal Block f... Read More
Gender:
ALL
Ages:
Between 7 years and 17 years
Trial Updated:
02/21/2024
Locations: CHOC Children's Hospital, Orange, California
Conditions: ACL Tear, Opioid Misuse, Pain, Anxiety
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Opioid-Free Orthopaedics
NCT04659317
Recruiting
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: The Emory Clinic, Atlanta, Georgia +2 locations
Conditions: Pain, Pain, Postoperative
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Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
NCT06246526
Recruiting
This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia
Conditions: Pain, Chronic Pain, Neuropathic Pain
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Mindful Waiting Room
NCT05433636
Recruiting
This will be a single-site, five-arm, parallel group randomized control trial involving patients seeking integrative healthcare. Four different styles of 5-minute, audio-recoded mindfulness practices delivered in the clinic waiting room will be compared with a 5-minute audio-recording about integrative healthcare. A secondary sub-analysis will investigate the most effective mindfulness practice style for patients presenting at the clinic with elevated anxiety, depression, or pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Anxiety State, Depressive State, Pain, Nausea, Fatigue, Cancer
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App Delivered Brief Mindfulness Intervention for Surgical Patients
NCT05433389
Recruiting
This will be a single-site, five-arm, parallel group randomized control trial involving patients undergoing knee or hip replacement surgery. The investigators will compare five different styles of 5-minute, audio-recoded mindfulness practices delivered via app 7 days before to surgery, 2 days before to surgery, 2 days after surgery, and 6 days after surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Pain, Anxiety State, Depressive State
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Brief Mindfulness for Foot and Ankle Pain
NCT05939843
Recruiting
This is a single-site, four-arm, parallel-group randomized clinical trial (RCT). The clinical effects of three different formats of a very brief (i.e., 3 minute), audio-recorded mindfulness intervention for foot and ankle patients will be investigated relative to a 3-minute audio-recoding about pain psychoeducation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Pain
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Mindfulness Intervention in Orthopedic Trauma Patients
NCT05634278
Recruiting
This project a single-site 3-arm parallel group randomized clinical trial conducted at a tertiary level 1 trauma center among patients undergoing operative fixation of a lower extremity fracture.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Pain, Anxiety
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Augmented Reality For MRI-Guided Interventions
NCT06224933
Recruiting
The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
01/24/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Infections, Pain, Diagnosis, Image Guided Needle Biopsy
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Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
NCT04269239
Recruiting
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several ph... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/10/2024
Locations: University of Texas Medical Branch, Galveston, Texas +2 locations
Conditions: Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
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Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience
NCT05074485
Recruiting
The first objective of the study is to evaluate whether a novel bio-signature (derived from a wide range of pro- and anti-nociceptive IL-1 family cytokine activity) will predict pain experienced and also release of underlying endogenous opioid neurotransmitters during an experimental nociceptive pain challenge, which will be performed while simultaneously quantifying mu-opioid receptor activity in the brain via \[11C\]-carfentanil PET neuroimaging in healthy subjects. Another objective is to eva... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/01/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Pain
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