There are currently 122 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
NCT06274008
Recruiting
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young athletes. The purpose of the current study is to determine if extended-release Bupivacaine Liposome Injectable Suspension (Exparel) is effective in decreasing at home narcotic consumption compared to standard Bupivacaine Adductor Canal Block f... Read More
Gender:
ALL
Ages:
Between 7 years and 17 years
Trial Updated:
02/21/2024
Locations: CHOC Children's Hospital, Orange, California
Conditions: ACL Tear, Opioid Misuse, Pain, Anxiety
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Opioid-Free Orthopaedics
NCT04659317
Recruiting
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: The Emory Clinic, Atlanta, Georgia +2 locations
Conditions: Pain, Pain, Postoperative
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Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
NCT06246526
Recruiting
This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia
Conditions: Pain, Chronic Pain, Neuropathic Pain
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Mindful Waiting Room
NCT05433636
Recruiting
This will be a single-site, five-arm, parallel group randomized control trial involving patients seeking integrative healthcare. Four different styles of 5-minute, audio-recoded mindfulness practices delivered in the clinic waiting room will be compared with a 5-minute audio-recording about integrative healthcare. A secondary sub-analysis will investigate the most effective mindfulness practice style for patients presenting at the clinic with elevated anxiety, depression, or pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: University of Utah, Salt Lake City, Utah
Conditions: Anxiety State, Depressive State, Pain, Nausea, Fatigue, Cancer
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Augmented Reality For MRI-Guided Interventions
NCT06224933
Recruiting
The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
01/24/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Infections, Pain, Diagnosis, Image Guided Needle Biopsy
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Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
NCT04269239
Recruiting
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery. Half of the subjects in this study will be assigned to an intervention that meets with a study therapist to discuss implementing healthy habits. The other half of subjects will assigned to an intervention group that meets with a study therapists to discuss implementing healthy sleep habits. Both groups will undergo several ph... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/10/2024
Locations: University of Texas Medical Branch, Galveston, Texas +2 locations
Conditions: Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
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Discovery and Analytical Validation of Inflammatory Bio-signatures of the Human Pain Experience
NCT05074485
Recruiting
The first objective of the study is to evaluate whether a novel bio-signature (derived from a wide range of pro- and anti-nociceptive IL-1 family cytokine activity) will predict pain experienced and also release of underlying endogenous opioid neurotransmitters during an experimental nociceptive pain challenge, which will be performed while simultaneously quantifying mu-opioid receptor activity in the brain via \[11C\]-carfentanil PET neuroimaging in healthy subjects. Another objective is to eva... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/01/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Pain
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VR to Reduce Pain/Anxiety During Painful Procedures
NCT04268901
Recruiting
This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing painful procedures in Phlebotomy, Radiology, Infusion, Orthopedics, Gastroenterology, and Immunology, amongst others, at CHLA, as measured by self- and proxy-report. Examples of the painful procedures include IV sticks, cast removals, allergy testing, and anorectal manometries.
Gender:
ALL
Ages:
Between 7 years and 21 years
Trial Updated:
10/25/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Phlebotomy, Orthopedics, Radiology, Pain, Anxiety, Virtual Reality, Allergy, Gastroenterology
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Vibratory Anesthesia in Trigger Finger Injections
NCT05405452
Recruiting
This study aims to compare the effectiveness of the use of no topical anesthesia, topical coolant, and the use of vibration in the reduction of pain during trigger finger injections. This will be done by randomizing patients who are diagnosed with trigger finger, warrant and choose to continue with a steroid injection into each of the respective anesthetic (or lack thereof) methods described. After conducting this and gathering data on the subjects pain felt, we will compare the analgesia from e... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2023
Locations: Banner UMC North Hills Clinic, Tucson, Arizona +1 locations
Conditions: Trigger Finger, Pain, Anesthesia, Local
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Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank
NCT04004286
Recruiting
This Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/10/2023
Locations: Naval Medical Center San Diego, San Diego, California +1 locations
Conditions: Pain
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AIMS Medical Outcomes Study
NCT04512755
Recruiting
This epidemiologic research is being conducted as an observational prospective case series outcomes study of the use of advanced integrative specialty medical care and its effect on adult and pediatric patients with chronic or serious illnesses or mental health disorders.
Gender:
ALL
Ages:
All
Trial Updated:
01/30/2023
Locations: AIMS Institute, Seattle, Washington
Conditions: Mental Health Issue, PTSD, Pain, Chronic Pain, Chronic Disease
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Pregabalin vs. Gabapentin on Reducing Opioid Usage
NCT04705480
Recruiting
This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid pain medications to decrease the amount of opioid pain medication usage in single-system orthopedic trauma patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: Charleston Area Medical Center"s Level 1 Trauma Center, Charleston, West Virginia
Conditions: Analgesics, Gabapentin, Injuries, Narcotics, Pain, Trauma
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