There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Passive VS Active VR on HPT Using the Thermal Sensory Analyzer With a Peltier-Based Contact Thermode
NCT05836649
Recruiting
This is a prospective, crossover study of healthy participants evaluating the impact of passive vs. active virtual reality (VR) games on heat pain threshold (HPT).
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
08/16/2023
Locations: Lucile Parkard Children's Hospital, Stanford, California
Conditions: Pain, Anxiety
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Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)
NCT04082533
Recruiting
In this study, total knee replacement patients will be determined to be stiff or non-stiff preoperatively. Stiffness designation is determined by preoperative range of motion (if flexion is < 100 degrees, or extension lag is > 10 degrees). The stiff and non-stiff groups will both be randomized to two groups to receive either intravenous hydrocortisone or a placebo at 3 intervals postoperatively. Patients will be followed up with in hospital and via the phone on postoperative day (POD) 1 and 2, a... Read More
Gender:
All
Ages:
Between 18 years and 83 years
Trial Updated:
08/15/2023
Locations: Hospital for Special Surgery, New York, New York
Conditions: Pain, Arthrofibrosis, Osteoarthritis, Knee
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Vibratory Anesthesia in Trigger Finger Injections
NCT05405452
Recruiting
This study aims to compare the effectiveness of the use of no topical anesthesia, topical coolant, and the use of vibration in the reduction of pain during trigger finger injections. This will be done by randomizing patients who are diagnosed with trigger finger, warrant and choose to continue with a steroid injection into each of the respective anesthetic (or lack thereof) methods described. After conducting this and gathering data on the subjects pain felt, we will compare the analgesia from e... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/14/2023
Locations: Banner UMC North Hills Clinic, Tucson, Arizona +1 locations
Conditions: Trigger Finger, Pain, Anesthesia, Local
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Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank
NCT04004286
Recruiting
This Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/10/2023
Locations: Naval Medical Center San Diego, San Diego, California +1 locations
Conditions: Pain
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Hip Arthroscopy Postoperative Opioid Demands
NCT04094701
Recruiting
This study will be a prospective, single-blinded, randomized controlled trial (RCT), investigating the influence of the number of opioid pills prescribed following primary hip arthroscopy. All patients who sign the consent form will be enrolled in the suited and randomized to one of the two treatment arms. The intervention group will receive 5 Norco pills, gabapentin (30 mg, once daily for 10 days following surgery), and Tylenol (1000 mg, three times daily for 10 days following surgery) while th... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/28/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Opioid Use, Pain, Femoral Acetabular Impingement, Labral Tear, Glenoid
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Memory & Conditioning Under Anesthesia
NCT04062123
Recruiting
The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena The study will occur over 5 visits and involves no long-term follow up.
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
07/03/2023
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Anesthesia, Pain
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PENG vs. FIC Block for Hip Fracture ED Patients
NCT05102760
Recruiting
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1. Elderly patients with hip fractures commonly present to the ED, and their injury can be painful. Commonly used opioid pain regimens can have deleterious side effects, especially in elderly patients, like somnolence, delirium, hypotension and respiratory depression. The fascia iliac... Read More
Gender:
All
Ages:
Between 18 years and 110 years
Trial Updated:
07/02/2023
Locations: Maimonides Medical Center, Brooklyn, New York
Conditions: Pain, Hip Fracture
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Pain Sensitivity During Puberty
NCT05145595
Recruiting
Aim 1- To examine the differences in pain sensitivity between adolescents at early vs. mid pubertal status Aim 2- To determine the relationships between sex hormone levels and pain sensitivity Exploratory Aim 1- To determine the effect of pubertal maturation on pain sensitivity Exploratory Aim 2- To identify parameters related to who will develop chronic pain during puberty Hypothesis 1- Adolescents in early pubertal status will have higher pain ratings and lower pain modulation capabilities co... Read More
Gender:
All
Ages:
Between 9 years and 16 years
Trial Updated:
06/09/2023
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Pain
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Effects of Dronabinol in Opioid Maintained Patients
NCT04025359
Recruiting
Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of opioid-related outcomes. Pain sensitivity will be measured using a technique called the (QST) quantitative sensory testing, which involves the administ... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/25/2023
Locations: VA Healthcare System, West Haven, Connecticut
Conditions: Pain
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Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
NCT04994249
Recruiting
To identify diagnostic and prognostic biomarker signatures of recovery versus having persisting high-impact chronic pain and functional disability in adults with Chronic Musculoskeletal Pain.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/10/2023
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Musculoskeletal Pain, Pain, Pain, Chronic, Joint Pain
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AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)
NCT04859296
Recruiting
This study will assess the analgesic, appetite-stimulating, and subjective effects of cannabigerol (CBG) alone and in combination with THC.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
03/13/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Appetite Loss, Abuse, Drug
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A Study to Assess the Safety of MEB-1170 in Healthy Subjects
NCT05748119
Recruiting
Primary Objective: To determine the safety and tolerability of single and multiple ascending oral doses of MEB-1170 in healthy subjects. Secondary Objectives: To determine the single and multiple oral dose pharmacokinetic profiles of MEB-1170 and the primary metabolite, M373, in healthy subjects. To determine the effect of food on the pharmacokinetic (PK) profile of a single oral dose of MEB-1170 in healthy subjects. To assess the pharmacodynamic (PD) response following single and multiple ora... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/17/2023
Locations: Labcorp Clinical Research Unit, Inc, Daytona Beach, Florida
Conditions: Pain
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