Texas is currently home to 4875 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Diuretics and Volume Overload in Early CKD
Recruiting
Almost 15% of Americans have chronic kidney disease (CKD), with an even higher rate in Veterans due to common risk factors such as high blood pressure and diabetes. People with CKD have a high risk of cardiovascular (CV) diseases, such as heart attacks, heart failure, and strokes. Extra fluid in the body, called volume overload, may lead to CV disease in people with CKD. It is unknown if volume overload develops in the earliest stages of CKD, when treating it with common, inexpensive medicines c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Chronic Kidney Disease, Hypertension
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
Recruiting
This project uses both transcriptomic- and genomic-level data to identify mechanisms of individual responses to glucagon-like peptide-1 (GLP-1) in Mexican-Americans with prediabetes. The GLP-1 hormone is essential for glucose reduction, weight loss, cardiovascular risk reduction, and renal protection. Newly discovered mechanisms will illuminate causal links between disease genotype and phenotype, which may ultimately guide personalized therapeutic approaches for type 2 diabetes, prediabetes, obe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: UTHealth Clinical Research Unit (CRU) at UT Brownsville, Brownsville, Texas
Conditions: PreDiabetes
Stroke Thrombectomy and Aneurysm Registry
Recruiting
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brai... Read More
Gender:
ALL
Ages:
Between 1 year and 120 years
Trial Updated:
12/05/2024
Locations: The University of Texas Medical Branch at Galveston, Galveston, Texas
Conditions: Stroke, Thromboses, Intracranial, Aneurysm, Brain
realMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL
Recruiting
The realMIND study is a multicenter, observational study intended to further characterize the safety and effectiveness data of US patients (with a focus on racial and ethnic minority patients) with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), treated with tafasitamab in combination with lenalidomide.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Diffuse Large B-cell Lymphoma
Young Houston Emergency Opioid Engagement System
Recruiting
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder. The investigators also intend to understand the prevalence of opioid overdoses and OUD among youth in Houston.
Gender:
ALL
Ages:
Between 13 years and 17 years
Trial Updated:
12/05/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use, Substance Use Disorders
Post-Market Study to Assess iTind Safety in Comparison to UroLift
Recruiting
The study objective is to evaluate the safety of the iTind device comparied to UroLift.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
12/05/2024
Locations: Midtown Urology Associates, Austin, Texas
Conditions: Benign Prostatic Hyperplasia (BPH)
Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Recruiting
This phase I trial identifies the best dose and clinical benefit of giving pemigatinib following standard induction chemotherapy in patients with newly diagnosed acute myeloid leukemia. Pemigatinib selectively inhibits FGFR (fibroblast growth factor receptor) activity, a receptor that may contribute to the growth of leukemia cells. The genetic changes responsible for activating the growth of leukemia cells can be unique to each patient and can change during the course of the disease. Chemotherap... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Conditions: Acute Myeloid Leukemia
Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
Recruiting
The purpose of this study is to compare the efficacy and side effects magnetic seizure therapy (MST) and electroconvulsive therapy (ECT) in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD).
Gender:
ALL
Ages:
Between 22 years and 85 years
Trial Updated:
12/05/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Bipolar Disorder
Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation
Recruiting
To determine the utility of diffusion tensor magnetic resonance imaging in the preoperative workup of children with intractable epilepsy referred for surgery.
Gender:
ALL
Ages:
Between 0 days and 18 years
Trial Updated:
12/05/2024
Locations: UTHealth & Children's Memorial Hermann Hospital, Houston, Texas
Conditions: Intractable Epilepsy
Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation
Recruiting
Demonstrate the impact of the Molecular Microscope Diagnostic System as the standard of care for heart transplant patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Annette C. and Harold C. Simmons Transplant Institute, BaylorScott&White Research Institute, Dallas, Texas
Conditions: Cardiac Transplant Disorder
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
Recruiting
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
Gender:
ALL
Ages:
Between 3 years and 18 years
Trial Updated:
12/05/2024
Locations: UTHealth & Children's Memorial Hermann Hospital, Houston, Texas
Conditions: Spastic Diplegia
Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars
Recruiting
The purpose of this study is to compare the efficacy of GentleWave versus EdgePro irrigation in the disinfection of infected root canals of human permanent teeth with necrotic pulp.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Pulp Necroses