Texas is currently home to 4875 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Real-time Personalized Brain State-dependent TMS After Stroke
Recruiting
Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic hand function after stroke. This project will test whether personalized brain state-dependent TMS can activate the residual corticospinal tract better than standard TMS, and evaluate the relationship between this activation and hand motor impairment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Stroke
Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool
Recruiting
The purpose of this study is to assess the impact of a semi-structured intraoperative anesthesia handoff tool on patient outcomes and to assess the validity of the 5-Factor Perceived Shared Mental Model Scale (5-PSMMS) in a healthcare setting and whether the perception of Shared Mental Model (SMM) mediates the effect of the intraoperative handoff tool on postoperative outcomes
Gender:
ALL
Ages:
Between 18 years and 105 years
Trial Updated:
12/04/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Post-operative Complications
Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas with Child-Pugh-B Cirrhosis
Recruiting
This is a single-arm, phase II study of patients with advanced liver cancer or hepatocellular carcinoma (HCC) who are eligible for first-line treatment with T300+D. The invesitgators hypothesize that T300+D will be safe and tolerated in CP-B patients with HCC. HCC mostly affects disadvantaged populations with higher rates among racial/ethnic minorities, who are often not included in clinical trials (i.e., Hispanics, Blacks, underserved, low socioeconomic status) and present with more severe dise... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: UT Health San Antonio, San Antonio, Texas
Conditions: Hepatocellular Carcinoma, Cirrhosis, Liver
MISC-IPV: a Community-Based Intervention for Children Traumatized by Intimate Partner Violence
Recruiting
This study adapts and evaluates preliminary outcomes of the Mediational Intervention for Sensitizing Caregivers (MISC) for women and children of color who have survived domestic violence.
Gender:
ALL
Ages:
Between 7 years and 65 years
Trial Updated:
12/04/2024
Locations: University of Houston, Houston, Texas
Conditions: MISC Intervention, Treatment as Usual
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Recruiting
This Phase 3 study is a randomized, double-blind, vehicle-controlled, multiple-center, parallel study to evaluate efficacy and safety of ENERGI-F703 GEL compared with vehicle control in subjects with Wagner Grade 1 to Grade 2 diabetic foot ulcers. Baseline target ulcer size (\<16 cm2 vs ≥16 cm2 ) will be included as a stratification factor. Subjects will be randomized 1:1 to receive ENERGI-F703 GEL or vehicle control using an interactive web response system for randomization to automatically ass... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: Mt. Olympus Medical Research, Houston, Texas
Conditions: Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline
Recruiting
The goal of this clinical study is to investigate the effectiveness of non-invasive stimulation to enhance cognitive control abilities in cognitively healthy adults and older adults diagnosed with mild cognitive disorder (MCI). The main questions it aims to answer are: * whether it is possible to restore various cognitive functions in older adults diagnosed with MCI by delivering theta burst stimulation (TBS), a form of transcranial magnetic stimulation, and * whether closed-loop TBS is able to... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/04/2024
Locations: Health Discovery Building, Austin, Texas
Conditions: Mild Cognitive Impairment
Enhancing Psychotherapy for Veterans and Service Members with PTSD and Anxiety
Recruiting
The goal of this clinical trial is to compare two different intensive formats of delivering cognitive-behavioral treatment for people with PTSD and anxiety disorders. The main questions it aims to answer are: * Is iTCBT delivered in individual and group formats more effective than TAU in improving anxiety symptoms and quality of life? * For treatment non-responders, is iTCBT-Enhanced more effective than TAU improving anxiety symptoms and quality of life? * Does iTCBT-Individual produce a larger... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: Posttraumatic Stress Disorder, Anxiety Disorders
The Establishment of a Registry and a Biorepository of Patients With Suspected Amniotic Fluid Embolism (AFE)
Recruiting
To establish a clinical registry of suspected cases of AFE. The existing registry will be migrated to a new platform,
Gender:
ALL
Ages:
All
Trial Updated:
12/04/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Amniotic Fluid Embolism
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Recruiting
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: * Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)? * Can reliable biomarkers for JoHD be found in brain structure and function? Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations... Read More
Gender:
ALL
Ages:
Between 6 years and 30 years
Trial Updated:
12/04/2024
Locations: University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
intenSive UpPer Extremity Recovery Program for Chronic Stroke (SUPER)
Recruiting
The purpose of this study is to Investigate the feasibility of a high-quality, high-dose, high-intensity upper extremity therapy program and to assess the treatment effects of a high-quality, high-dose, high-intensity upper extremity therapy program on functional outcomes, motor impairment, and quality of life
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/04/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Chronic Stroke
PRIME: PReservIng Memory in Epilepsy
Recruiting
In this study, participants will receive unilateral Deep Brain Stimulation (DBS) for treatment of epilepsy, with network-based stimulation targets specifically defined using a stereo-electro-encephalographic evaluation and chronic recordings using the Medtronic Percept™ primary cell (PC) Neurostimulator DBS System with BrainSense™ Technology. The hypothesis is that, compared to no stimulation or to standard duty cycle high frequency stimulation, epilepsy neuromodulation using low frequency stimu... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/04/2024
Locations: The University of Texas Science Center at Houston, Houston, Texas
Conditions: Mesial Temporal Lobe Epilepsy
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Recruiting
Tagraxofusp is a protein-drug conjugate consisting of a diphtheria toxin redirected to target CD123 has been approved for treatment in pediatric and adult patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN). This trial aims to examine the safety of this novel agent in pediatric patients with relapsed/refractory hematologic malignancies. The mechanism by which tagraxofusp kills cells is distinct from that of conventional chemotherapy. Tagraxofusp directly targets CD123 that is pre... Read More
Gender:
ALL
Ages:
Between 1 year and 21 years
Trial Updated:
12/04/2024
Locations: University of Texas, Southwestern, Dallas, Texas
Conditions: Hematologic Malignancy, AML, ALL, BPDCN, MDS, Lymphoblastic Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Hodgkin Lymphoma, Mixed Phenotype Acute Leukemia, Acute Undifferentiated Leukemia