Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
HIV+ Deceased Donor Heart Transplant Study for HIV+ Recipients
Recruiting
This will be a prospective single-center interventional trial to compare the outcomes of HIV-positive heart transplant recipients by the HIV status of the donor; HIV-positive vs. HIV-negative and learn whether heart organ transplantation from HIV+ deceased donors is as safe and effective in HIV+ recipients as transplants from HIV- deceased donors. Patient will undergo standard evaluation for eligibility of transplantation by the primary heart transplant team. If patient meets eligibility criter... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: HIV Infection, Advanced End Stage Heart Failure
Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training
Recruiting
The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual flight simulations, the Precision Instrument Control Task (PICT). The flight simulation test will be conducted at two separate timepoints while the subject is receiving a Functional Magnetic Resonance Imaging (fMRI) scan to evaluate which anatomic and functional brain fu... Read More
Gender:
ALL
Ages:
Between 18 years and 54 years
Trial Updated:
01/13/2025
Locations: Joint Base San Antonio - Randolph & Lackland, San Antonio, Texas
Conditions: Cognitive Performance
Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine
Recruiting
The primary objective of this effort will be to optimize and operationalize innovative passive surveillance systems and in parallel, the effort will identify, evaluate, and transition groundbreaking new technologies in diagnostics for operationalization. To meet the objective and execute the deliverables for this program of effort, the A\&M Breathalyzer PROTECT Kiosk will be tested, modified and validated at Brooke Army Medical Center (BAMC). The collaborative efforts between the PI, Dr. Michae... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/13/2025
Locations: Brooke Army Medical Center, Fort Sam Houston, Texas
Conditions: COVID-19, SARS CoV 2 Virus, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
Traction vs. No Traction in Colonic ESD
Recruiting
The goal of this prospective, randomized, controlled trial conducted at Baylor St. Luke's Medical Center is to compare the effectiveness and clinical outcomes of using a traction device in colonic endoscopic submucosal dissection (ESD) to those of using conventional ESD. The investigators of this study hypothesize that use of the traction device will help expedite colonic endoscopic submucosal dissections.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Gastrointestinal Neoplasm
Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture
Recruiting
The purpose is to find out if incorporation of an intraoperative electro auricular acupuncture protocol when added to a standard multimodal analgesic regimen for patients undergoing surgery to repair lower leg fracture under spinal anesthesia will help reduce postoperative opioid use.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Recruiting
The purpose is to find out if intraoperative acupuncture performed by needling PC 6 and LI4 point bilaterally, and Yin Tang point will help reduce the incidence postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy when added to a prophylactic regimen consisting of ondansetron and dexamethasone. The hypothesis is that the addition of this acupuncture treatment to ondansetron and dexamethasone given for prophylaxis will help reduce the incidence of postoperative na... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative, Pain, Postoperative
Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
Recruiting
This randomized controlled trial will test the hypothesis that patients receiving an intraoperative auricular acupuncture protocol will require less postoperative opioid analgesic use compared to those who do not receive acupuncture in the setting of a multimodal analgesic protocol for patients receiving surgery to repair distal radius fractures at a Level 1 trauma center under brachial plexus anesthesia with sedation.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Radius Fracture Distal, Pain, Postoperative
Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
Recruiting
The purpose of the study is to assess vascular function in African Americans, Hispanic and Caucasian Americans to better understand racial differences in cardiovascular health. The investigators will further investigate the affect of Beetroot juice on the vascular function of all participants.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/13/2025
Locations: University of Texas at Austin, Austin, Texas
Conditions: Healthy Adults
Cool Prime Comparative Effectiveness Study for Mild HIE
Recruiting
To determine effectiveness of therapy to improve neurodevelopmental outcomes in infants with mild HIE. To determine the adverse effects of Therapeutic Hypothermia (TH) in mild HIE on the neonate and his/her family. Determine heterogeneity of the treatment effect across key subgroups obtained in the first 6 hours after birth prior to the decision to initiate therapy.
Gender:
ALL
Ages:
35 weeks and above
Trial Updated:
01/13/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Mild Hypoxic Ischemic Encephalopathy of Newborn
The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder
Recruiting
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use. Currently there is no guidance for speech language pathologists (SLPs) as to the language of intervention for bilingual children with DLD with differing degrees of proficiency with English or Spanish. This project will examine the relationship between relative language proficiency and the language of intervention, considering monol... Read More
Gender:
ALL
Ages:
Between 4 years and 6 years
Trial Updated:
01/12/2025
Locations: School Districst, Houston, Texas
Conditions: Developmental Language Disorder, Language Impairment
Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies
Recruiting
A Phase 1, first-in-human study of EP31670, a dual BET and CBP/p300 inhibitor in patients with targeted advanced solid tumors and Hematological Malignancies
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/12/2025
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Castrate Resistant Prostate Cancer, NUT Carcinoma, Chronic Myelomonocytic Leukemia, Myelofibrosis
Transcutaneous Auricular Neurostimulation After Lumbar Fusion Surgery
Recruiting
The purpose of this study, entitled "Delivering Transcutaneous Auricular Neurostimulation as an Adjunct Non-Opioid Pain Management Therapy for Patients Undergoing Lumbar Fusion Surgery", is to demonstrate whether transcutaneous auricular neurostimulation (tAN) can non-invasively reduce the perception of pain in patients undergoing lumbar fusion surgery. tAN is placed on and around the ear to non-invasively stimulate branches of the vagus and trigeminal nerves and modulate specific brain regions... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/10/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Pain, Postoperative, Opioid Use, Lumbar Spine Injury