Texas is currently home to 4882 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Optimizing Intervention Options for Toddlers With Early Social Communication Delays
Recruiting
Improving social communication outcomes for toddler siblings of children with autism, who are at high risk for multiple language and communication deficits beyond autism, has important public health implications. The proposed study is a pilot sequential multiple random assignment trial of 44 high-risk siblings that examines the feasibility, acceptability, and preliminary effects of an adaptive intervention for social communication. Evaluating effective parent-mediated communication support strat... Read More
Gender:
ALL
Ages:
Between 11 months and 18 months
Trial Updated:
07/03/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Autism Sibling
Suicide Treatment Alternatives for Teens
Recruiting
Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.
Gender:
ALL
Ages:
Between 12 years and 18 years
Trial Updated:
07/03/2024
Locations: UT Southwestern Medical Center/Children's Health, Dallas, Texas
Conditions: Suicidal Ideation
Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App
Recruiting
The purpose of this study is to demonstrate the feasibility and utility of SIT delivered asynchronously (self-paced) via fully virtual platform with and without the aid of a mobile health application and to determine initial change over baseline in terms of reduction in PTSD symptoms and improvement in resiliency in participants receiving the virtual SIT prototype, using Linear Mixed Models (LMMs),
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
07/02/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: PTSD, Trauma and Stressor Related Disorders, Traumatic Brain Injury
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Recruiting
This is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and anti- tumor activity of ETX-19477, a novel reversible small molecule inhibitor of PARG.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced or Metastatic Solid Tumors, Breast Cancer, Ovarian Cancer, Prostate Cancer, Epithelial Ovarian Cancer, BRCA2 Mutation, ER+ Breast Cancer, Castrate Resistant Prostate Cancer, BRCA1 Mutation, BRCA Mutation, Endometrial Cancer, Colorectal Cancer, Gastric Cancer
Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC)
Recruiting
Esophagectomy is the cornerstone of the curative treatment of esophageal carcinoma. Despite this treatment, patients can suffer from locoregional or distant metastatic disease and only a very selected group of patients can be cured: mostly those with recurrence in one single organ. Brain metastases are rare after esophagectomy for cancer, but they have a serious impact on survival. Agressive treatment is often moren difficult for brain metastases compared to other metastases and some risk facto... Read More
Gender:
ALL
Ages:
All
Trial Updated:
07/02/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Esophageal Neoplasms, Esophagectomy, Brain Metastases
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Recruiting
This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.
Gender:
ALL
Ages:
All
Trial Updated:
07/02/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Neoplasms
The Effect of Clinic Visit Audio Recordings for Self-management in Older Adults
Recruiting
The objective of this study is to conduct a multisite trial evaluating the impact of adding an audio recording of clinic visits (AUDIO) to usual care in older adults with multimorbidity, including diabetes, compared to After Visit Summary (AVS) alone (Usual Care; UC).
Gender:
ALL
Ages:
65 years and above
Trial Updated:
07/01/2024
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Diabetes
Increasing HIV/STI Home Testing Via a Digital Intervention Among Black Women
Recruiting
The proposed intervention is a web-based intervention guided by theoretical components to increase HIV home testing among Black women at risk for HIV and sexually transmitted infections (STIs) in a HIV hotspot in the South. The intervention will promote using the home test, linkage to care, and linkage to pre-exposure prophylaxis (PrEP) evaluation. The intervention has the potential to be implemented on a large scale and tailored based on location and population to increase testing, treatment, a... Read More
Gender:
FEMALE
Ages:
Between 15 years and 59 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins Bloomberg School of Public Health, Austin, Texas
Conditions: Hiv, Sexually Transmitted Diseases, Economic Problems
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: Hendrick Medical Center, Abilene, Texas
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
A Culturally Tailored Scalable Asthma Intervention for Hispanic Children (Asthma Guardian)
Recruiting
This is a two-arm, parallel design, randomized, controlled pilot trial comparing access to Asma Guardián, a culturally tailored multi-component app-based asthma intervention for Hispanic/Latinx school age children with asthma, to usual care.
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
06/28/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Asthma in Children
LSTR in Chevron Osteotomy
Recruiting
The goal of this clinical trial is to determine if performing a lateral soft tissue release during a Chevron osteotomy (or Akin osteotomy when appropriate) for bunions leads to better correction without added complications in 200 patients over the age of 18 years old with the capacity to consent and mild to moderate bunions that are determined to benefit from Chevron osteotomies by one of the IRB approved study physicians. The main questions it aims to answer are: How does the addition of a lat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Houston Methodist Research Institute, Houston, Texas
Conditions: Bunion
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Recruiting
Vascular Ehlers-Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein. This impacts the body's connective tissue and makes people with VEDS at high risk of spontaneous aortic and arterial rupture, pneumothorax, and hollow organ perforation across the age spectrum. Given this risk and high potential for lethality, VEDS is considered the most severe type of Ehlers-Danlos Syndrome. In addition, many patients experience chronic pain... Read More
Gender:
ALL
Ages:
Between 12 years and 45 years
Trial Updated:
06/27/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Vascular Ehlers-Danlos Syndrome