Texas is currently home to 5024 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
NCT04443088
Recruiting
Phase 1, open-label dose-escalation study to determine the MTD of INV-1120 and RP2D, and to assess the DLT of INV-1120 as a single agent or in the combination with pembrolizumab. The safety, tolerability, and PK of INV-1120 as a single agent or in the combination with pembrolizumab will be assessed in adult patients with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: START, San Antonio, Texas
Conditions: Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma, Solid Tumor, Unspecified, Adult, Tumor, Solid
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Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: Baylor, Scott & White Health (BSW Health), Texas City, Texas
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
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First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector
NCT04053283
Recruiting
To characterise the safety and tolerability of NG-641 in patients with metastatic or advanced epithelial tumours.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: MD Anderson, Houston, Texas
Conditions: Metastatic Cancer, Epithelial Tumor
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A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy
NCT04015141
Recruiting
The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome (Cohort 1) and partial-onset seizures (POS) (Cohort 2).
Gender:
All
Ages:
Between 1 month and 18 years
Trial Updated:
06/19/2023
Locations: Child Neurology Consultants of Austin, Austin, Texas
Conditions: Pediatric Epileptic Syndrome, Partial-onset Seizures
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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
NCT03113643
Recruiting
This research study is studying a drug as a possible treatment for diagnosis of AML, BPDCN and high-risk MDS. The interventions involved in this study are: SL-401 Azacitidine Venetoclax
Gender:
All
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Blastic Plasmacytoid Dendritic Cell Neoplasm
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New Pediatric Patching Method to Improve Compliance
NCT02236351
Recruiting
This project will assess whether there is a significant difference in compliance with patching in amblyopic patients whose parents are instructed to pinch the superior and inferior edges of the patch before applying (in order to improve comfort) versus patients whose parents are instructed to place the patch evenly around the orbit.
Gender:
All
Ages:
7 years and below
Trial Updated:
06/19/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Amblyopia, Strabismus
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A Study of MT-101 in Subjects With CD5+ Relapsed/Refractory TCL
NCT05138458
Recruiting
This is a Phase 1/2 study to test the safety, tolerability, and efficacy of the investigational agent MT-101 in patients with T cell Lymphoma. MT-101 is made with myeloid cells collected from the patient's blood. The myeloid cells are modified and later infused back into their veins. The modified myeloid cells recognize the tumor cells and are designed to target and kill them.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2023
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Cell Therapy, Lymphoma, T-Cell, Peripheral, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides, Adoptive Cellular Immunotherapy
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A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer
NCT05198804
Recruiting
This is a Phase 1/2 study to evaluate the safety, clinical activity, pharmacokinetics (PK), and pharmacodynamics (PD) of ZN-c3 in combination with niraparib in subjects with platinum-resistant ovarian cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/16/2023
Locations: Texas Oncology-Fort Worth Cancer Center, Fort Worth, Texas
Conditions: Ovarian Cancer, Platinum-resistant Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
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BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
NCT05161429
Recruiting
An observational study of electronic patient data to compare diabetes medications and to determine which ones offer the best balance of risks and benefits.
Gender:
All
Ages:
30 years and above
Trial Updated:
06/16/2023
Locations: Baylor Scott & White, Dallas, Texas
Conditions: Diabetes Mellitus, Type 2
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Endoscopic Strip Craniectomy for Treatment of Sagittal Craniosynostosis
NCT04721769
Recruiting
Endoscopic strip craniectomy (ESC) with post-operative helmeting is the gold-standard treatment for isolated, non-syndromic sagittal craniosynostosis in children under 6 months of age as it is has been demonstrated to reduce perioperative morbidity when compared to more invasive procedures such as cranial vault remodeling. ESC is frequently performed with or without the use of lateral osteotomies with technical selection being largely based on surgeon preference. Previous studies have shown that... Read More
Gender:
All
Ages:
6 months and below
Trial Updated:
06/16/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Craniosynostosis, Sagittal
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Study of Individuals Affected With Hypoplasminogenemia
NCT03797495
Recruiting
This is an Investigator initiated retrospective and prospective single cohort study. The study will utilize an international registry and develop a specimen biobank to provide an improved understanding of the natural history of hyposplasminogenemia, to elucidate the heterogeneity of phenotypic expression, identify markers to predict disease course, and inform improved therapeutic modalities
Gender:
All
Ages:
All
Trial Updated:
06/16/2023
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Plasminogen Deficiency
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LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
NCT05303636
Recruiting
The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12 months (13 medication cycles) of investigation in comparison to non-hormonal contraceptive methods. Secondary objectives include further evaluating the impact of LF111 and DRSP 3.5 mg chewable tablets on BMD and bone turnover after 12 months (13 medication cycles) in comparison to non-hormonal contraceptive methods and a... Read More
Gender:
Female
Ages:
Between 14 years and 45 years
Trial Updated:
06/15/2023
Locations: Corpus Christi Women's Clinic, Corpus Christi, Texas
Conditions: Change in Bone Mineral Density, Bone Loss
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