Texas is currently home to 4888 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
Recruiting
This is a multi-center, single-agent, open-label, Phase I study of APG-2575. The study consists of the dose escalation stage and the dose expansion stage.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2024
Locations: MDACC, Houston, Texas
Conditions: Hematologic Malignancies
Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation
Recruiting
The purpose of this study is to determine the safety and effectiveness (how well it works) of a new experimental ultrasound bath device that uses low frequency ultrasound (LFU) that may or may not help healing.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
08/15/2024
Locations: University of Texas Medical Branch, Galveston, Galveston, Texas
Conditions: Osteo Arthritis Knee, Age Related Osteoporosis, Pain, Knee Joint Contracture
South Asians and Coronary Plaque Registry
Recruiting
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Coronary Artery Disease, Heart Diseases
Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
Recruiting
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: Texas A&M University, College Station, Texas
Conditions: Spinal Cord Injuries, Neuropathic Pain
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children
Recruiting
This multisite study seeks to understand whether and how pulse oximeter accuracy varies across children with different skin colors in real world clinical settings. Many factors can affect how well pulse oximeters work; for example, movement and even fingernail polish. Some studies in adults show that skin color may also affect the pulse oximeter reading. In this study, we will explore pulse oximeter accuracy in children of all skin colors who are undergoing cardiac catheterizations. The study wi... Read More
Gender:
ALL
Ages:
Between 4 weeks and 18 years
Trial Updated:
08/14/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Pediatric ALL, Cardiac Defect
Personalized Behavioral Nutrition Intervention in Older AAs With T2D
Recruiting
The rapid growth rate and unique challenges as a new immigrant group call for a better understanding of the social and health needs of the older Asian Americans (AAs) population. Overwhelming numbers of AAs, a fast-growing first-generation immigrant group, suffer from type 2 diabetes (T2D) and its consequences of poorly controlled blood glucose. For the older AAs, there are higher prevalence rates, worse diabetes control, and higher rates of complications due to limited English proficiency and h... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/14/2024
Locations: The University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Type 2 Diabetes
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Recruiting
This phase III trial compares the effect of adding surgery to a standard of care immunotherapy-based drug combination versus a standard of care immunotherapy-based drug combination alone in treating patients with kidney cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, pembrolizumab, and avelumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: UT Southwestern Simmons Cancer Center - RedBird, Dallas, Texas
Conditions: Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
Recruiting
This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: MD Anderson in The Woodlands, Conroe, Texas
Conditions: Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
Study of Selected X-Linked Disorders: Aicardi Syndrome
Recruiting
Based on our current understanding of Aicardi syndrome, the condition is hypothesized to occur due to a genetic change on the X-chromosome. The research team is investigating Aicardi syndrome to identify the specific gene location associated with the disorder. The investigators are collecting blood and skin biopsy samples from patients and their parents. A permanent cell line is prepared and DNA from the blood and skin samples and cell lines is isolated and then used for genetic testing. The cur... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/14/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Aicardi Syndrome, Brain Disorders
Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)
Recruiting
Study focuses on determining if daily versus every-other-day (EOD) oral iron at the same dose per kilogram per day will achieve similar incidence of iron replete status at 36 weeks post-menstrual age in premature neonates
Gender:
ALL
Ages:
Between 26 weeks and 32 weeks
Trial Updated:
08/13/2024
Locations: CHRISTUS Children's, San Antonio, Texas
Conditions: Very Low Birth Weight Infant, Premature Infants, Anemia of Prematurity, Iron Deficiency, Anaemia in Children, Extremely Low Birth Weight
The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)
Recruiting
This is an open-label, multicenter study to evaluate the safety, tolerability, and efficacy of HMPL-523 in adult subjects with ITP.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2024
Locations: Texas Oncology San Antonio Medical Center, San Antonio, Texas
Conditions: Immune Thrombocytopenia, Blood Platelet Disorder, Hematologic Diseases, Purpura, Thrombocytopenic, Purpura, Blood Coagulation Disorder, Thrombotic Microangiopathies, Hemorrhagic Disorders, Autoimmune Diseases, Immune System Diseases, Hemorrhage, Pathologic Processes, Skin Manifestations, Thrombocytopenia, Purpura, Thrombocytopenic, Idiopathic, Primary Immune Thrombocytopenia, ITP - Immune Thrombocytopenia
US National OCS Liver Perfusion (OLP) Registry
Recruiting
This Registry is a sponsor-initiated, multi-center, observational, post-approval registry with an independent academic oversight. TransMedics has contracted with United Network for Organ Sharing (UNOS) the Federal manager of the U.S. national transplant outcomes registry to obtain data that is routinely collected by the Organ Procurement and Transplantation Network (OPTN) on all transplanted organs in the U.S. for both the OCS liver transplanted patients as well as patients transplanted using o... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/13/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Liver Transplant