Texas is currently home to 4876 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Hepatic Histopathology in Urea Cycle Disorders
Recruiting
This is a multi-site, retrospective chart review as well as a prospective study to evaluate histopathologic findings in liver samples from individuals with any UCD diagnosis. This study will be conducted at all Urea Cycle Disorders Consortium (UCDC) sites: Baylor College of Medicine in Houston, TX and Children's National Medical Center in Washington D.C.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Urea Cycle Disorder, Ornithine Transcarbamylase Deficiency, Citrullinemia 1, ARGI Deficiency, ASL Deficiency, Argininosuccinic Aciduria, ASS Deficiency, Hyperargininemia, Carbamyl Phosphate Synthetase Deficiency, NAGS Deficiency
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Texas Movement Disorder Specialist, Georgetown, Texas
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program?
Recruiting
The purpose of this study is find out if we can use simple tests (biomarkers) to tell us if a specific child would benefit most from CBT or from the low FODMAPs diet.
Gender:
ALL
Ages:
Between 7 years and 12 years
Trial Updated:
05/24/2024
Locations: Children's Nutrition Research Center, Houston, Texas
Conditions: Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Functional Bowel Disorder, Functional Abdominal Pain, Functional Abdominal Pain Disorders
Assessing the Impact of Botulinum Toxin Type A on Facial Wrinkles: A Comprehensive Clinical Investigation
Recruiting
A study conducting to see how well a treatment called Botulinum Toxin Type A works for reducing facial wrinkles. The study will help us understand if this treatment is safe and effective for making wrinkles on the face less noticeable.
Gender:
ALL
Ages:
Between 20 years and 65 years
Trial Updated:
05/23/2024
Locations: Global Aesthetics LLC, Cisco, Texas
Conditions: Wrinkle
Implementation and Evaluation of an Evidence-Based, Multilevel Lifestyle Intervention for Underserved and Rural Populations in South Texas
Recruiting
The purpose of this study is to enhance the current TSSC multilevel intervention delivered in Cameron and Hidalgo counties by adding additional components including an educational module on the risks of alcohol intake and its connection to cancer, as well as developing training and referral systems to address social determinants of health (SDOH) that negatively impact uptake of cancer prevention behaviors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Cancer Prevention
Massage Therapy After Thoracic or Lumbar Surgery
Recruiting
The purpose of this research is to look at the effect of massage therapy on the pain, anxiety, and quality of life that pediatric patients have after undergoing spinal fusion surgery. This is a single-site, prospective, randomized, interventional study design that will involve post-thoracic and post-lumbar spinal fusion surgeries of pediatric patients from 7 to 19 years of age that present to Cook Children's Medical Center in Fort Worth, Texas. These patients will be identified prior to their sc... Read More
Gender:
ALL
Ages:
Between 7 years and 19 years
Trial Updated:
05/22/2024
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
Phase II Clinical Trial of Interleukin-2 in AD
Recruiting
Neuroinflammation is a significant component of Alzheimer disease (AD). Our group recently demonstrated that regulatory T cells (Tregs) have a compromised phenotype and reduced suppressive function in AD patients, skewing the immune system toward a proinflammatory status and potentially contributing to disease progression. Low dose interleukin-2 (IL-2) is now viewed as a promising immunoregulatory drug with the capacity to selectively expand and restore functional Tregs. This study is a phase II... Read More
Gender:
ALL
Ages:
Between 50 years and 86 years
Trial Updated:
05/22/2024
Locations: Houston Methodist Research Institute, Houston, Texas
Conditions: Alzheimer Disease
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: St. David's South Austin Medical Center, Austin, Texas
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome
Recruiting
Single center, prospective, randomized, double-blind, pragmatic Phase 2 clinical study in severely injured trauma patients within hours of hospitalization who have survived initial resuscitation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: Healios Investigational Site, Houston, Texas
Conditions: Trauma, Adult Stem Cells
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
Recruiting
Heart failure (HF) with preserved left ventricular function (pEF) is difficult clinical syndrome to treat effectively with few evidence based therapies. Atrial fibrillation (AF) is now an important co-morbidity being observed in 43% of patients with HFpEF. Rhythm control has not been studied in this population. Catheter ablation and antiarrhythmic drugs are rhythm control therapies that have been used for treatment of AF without HF or HF with reduced systolic function but have not been widely ap... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/22/2024
Locations: TCAI at St. David's Hospital, Austin, Texas
Conditions: Atrial Fibrillation, Heart Failure, Diastolic Heart Failure
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Recruiting
The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulatory hemodynamics monitoring and HF (Heart Failure) therapies. The data collected will be used for retrospective studies, quality improvement, identifying research cohorts, and member-initiated research.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/21/2024
Locations: Austin Heart, Austin, Texas
Conditions: Heart Failure
An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
Recruiting
Open-label study of brexanolone infusion for the treatment of posttraumatic stress disorder in 20 adult women with PTSD. Primary Objective: To determine if brexanolone injection infused intravenously for 24 hours at up to 60 μg/kg/h reduces PTSD symptom severity in a group of non-veteran adult female subjects diagnosed with PTSD as assessed by the change from baseline in the PTSD Checklist for DSM-5 (PCL-5) total score and rate of remission at 12-weeks post infusion. Secondary Objectives * T... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/21/2024
Locations: University of Texas at Austin Dell Medical School, Austin, Texas
Conditions: Post-Traumatic Stress Disorder