Texas is currently home to 4888 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Endoscopic Strip Craniectomy for Treatment of Sagittal Craniosynostosis
Recruiting
* Endoscopic strip craniectomy (ESC) with post-operative helmeting is the gold-standard treatment for isolated, non-syndromic sagittal craniosynostosis in children under 6 months of age as it is has been demonstrated to reduce perioperative morbidity when compared to more invasive procedures such as cranial vault remodeling. ESC is frequently performed with or without the use of lateral osteotomies with technical selection being largely based on surgeon preference. * Previous studies have shown... Read More
Gender:
ALL
Ages:
6 months and below
Trial Updated:
07/26/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Craniosynostosis, Sagittal
Improving Independent Multi-joint Arm Control After Stroke
Recruiting
The purposes of this study include: 1. - To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2. - To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.
Gender:
ALL
Ages:
Between 40 years and 75 years
Trial Updated:
07/25/2024
Locations: University of Houston, Houston, Texas
Conditions: Stroke
Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy
Recruiting
This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about its impact on physical therapy outcomes. The aim of this project is to show the efficacy of a novel device, the Neubie direct current device, compared to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Spine & Rehab Specialists, El Paso, Texas
Conditions: Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites
PODER Familiar: Health Promotion for Latino Families of Children With IDD
Recruiting
The goal of this clinical trial is to test a culturally tailored health promotion intervention for children with IDD and their families. First investigators will conduct a single group design pilot study of a health promotion intervention, followed by second, a small-scale randomized control trial (RCT). of the intervention with Latino parents of children with intellectual and developmental disabilities (IDD) in the Chicago, Illinois and Austin, Texas areas. The following research questions will... Read More
Gender:
ALL
Ages:
Between 6 years and 100 years
Trial Updated:
07/25/2024
Locations: Steve Hicks School of Social Work, University of Texas at Austin, Austin, Texas
Conditions: Health-Related Behavior, Quality of Life, Psychological Distress, Diet, Healthy, Physical Inactivity
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Recruiting
Texas Biomedical Device Center (TxBDC) has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT). This technique uses brief pulses of vagus nerve stimulation to engage pro-plasticity neuromodulatory circuits during rehabilitation exercises. Preclinical findings demonstrate that VNS paired with rehabilitative training enhances recovery in multiple models of neurological injury, including stroke, spinal... Read More
Gender:
ALL
Ages:
Between 22 years and 79 years
Trial Updated:
07/25/2024
Locations: Baylor Scott & White Institute for Rehabilitation, Dallas, Texas
Conditions: Stroke, Chronic Stroke, Upper Extremity Paresis, Ischemic Stroke, Hemorrhagic Stroke
iotaSOFT Pediatric Study
Recruiting
Prospective, non-randomized, open-label study to evaluate the safety and efficacy of the iotaSOFT Insertion System when used to assist electrode array insertion during cochlear implant surgery in a pediatric population.
Gender:
ALL
Ages:
Between 9 months and 12 years
Trial Updated:
07/23/2024
Locations: Texas Childrens Hospital, Houston, Texas
Conditions: Hearing Loss, Sensorineural, Hearing Loss, Bilateral, Hearing Loss, Unilateral
A Coping Skills Program for Children With Asthma
Recruiting
Uncontrolled asthma in school-aged children is a significant public health problem. Latino children living in low-income contexts are at increased risk for uncontrolled asthma compared to non-Latino white children, and stress is an unaddressed factor in this disparity. Therefore, the purpose of the current study is to test an intervention program that teaches families skills to cope with asthma-related and other sources of stress. Specifically, the study will compare the effects of the combined... Read More
Gender:
ALL
Ages:
8 years and above
Trial Updated:
07/23/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Asthma in Children
Optimizing Beta Blocker Dosage in Women While Using the Wearable Cardioverter Defibrillator
Recruiting
The primary objective of this pilot study is to document the percentage achievement in effective HR control (average nighttime HR \< 70 bpm) during WCD use in a cohort of female patients with cardiomyopathy in an outpatient setting using continuous heart rate (HR) trends data from the WCD to optimize BB/ivabradine dosage, as compared to a prior historical control.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Texas Cardiology Associates of Houston, Kingwood, Texas
Conditions: Cardiomyopathies, Heart Failure
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: MD Anderson, Houston, Texas
Conditions: Diffuse Large B-cell Lymphoma
Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma
Recruiting
This study will assess the safety, tolerability, pharmacokinetics (PK) and the therapeutic potential of HDP-101 in patients with plasma cell disorders including multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Multiple Myeloma, Plasma Cell Disorder
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
Recruiting
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure and heart rate, time to onset and to maximal response, and the duration of response; to assess the safety of the product in this population; and to character... Read More
Gender:
ALL
Ages:
Between 12 years and 16 years
Trial Updated:
07/22/2024
Locations: Children's Medical Center of Dallas, Dallas, Texas
Conditions: Hypotension
SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.
Recruiting
SprmPik AI Assisted Sperm Selection Study SiD, an assistant for sperm selection during intracytoplasmic sperm injection in medically assisted reproduction: effect on fertilization, blastocyst formation, early pregnancy loss, and consistent practice. A prospective pilot study.
Gender:
ALL
Ages:
All
Trial Updated:
07/19/2024
Locations: Ovation Fertility - Austin, Austin, Texas
Conditions: Infertility