Texas is currently home to 4854 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis
NCT01315782
Recruiting
This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requiring mechanical ventilation and the possibility to predict multi-organ failure. The measurement of alveolar dead space used to require sophisticated equipment and time. New ventilators have microprocessors that allow rapid mathematical calculation with minimal intervention.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2023
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Sepsis, Severe Sepsis, Septic Shock, Multi-organ Failure
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Comparison of iLivTouch and FibroScan for the Assessment of Liver Fibrosis and Steatosis in Adult Patients in the US
NCT06051669
Recruiting
This is a multi-center, cross-sectional, and prospective study that will recruit patients from multiple hospitals or outpatient clinics in the USA to the comparison of iLivTouch and FibroScan for the assessment of liver fibrosis and steatosis in adult patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2023
Locations: Baylor University, Houston, Texas
Conditions: Liver Fibrosis, Fatty Liver
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Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations
NCT04042831
Recruiting
This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene mutations. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Bile Duct Adenocarcinoma, Fanconi Anemia Complementation Group Gene Mutation, Metastatic Bile Duct Carcinoma, PTEN Gene Deletion
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The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
NCT06016478
Recruiting
The purpose of this study is to examine the effect of 4 weeks of Citrulline supplementation on macro- and microvascular function during acute hyperglycemia in middle-aged and older adults with type 2 diabetes.
Gender:
ALL
Ages:
Between 40 years and 75 years
Trial Updated:
10/10/2023
Locations: TTU Kinesiology and Sport Management Building, Lubbock, Texas
Conditions: Type 2 Diabetes
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AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
NCT05211570
Recruiting
The primary objective is to define the safety and tolerability of AB8939 in patients with AML by determining the dose-limiting toxicities, the maximum tolerated dose, and the recommended dose for dose expansion study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse, Myelodysplastic Syndrome Acute Myeloid Leukemia
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FX Shoulder Prospective Clinical Study
NCT06078865
Recruiting
Prospective Multi-Center Registry on study subjects with implanted devices marketed and legally commercialized in the USA by FX Shoulder Solutions.
Gender:
ALL
Ages:
All
Trial Updated:
10/05/2023
Locations: Texas Orthopedic Specialists, Bedford, Texas
Conditions: Osteoarthritis Shoulder, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Shoulder
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Impact of an Enhanced Patient Reported Outcome Measurement (PROM) Strategy on PROM Completion Rates
NCT06078137
Recruiting
in clinical practice has been curbed by issues related to the variability in use of these tools for decision-making, and universally poor completion rates over time. Patients may not see the relevance of responding to questions about their health, and the results may not be reviewed by the clinician or presented and visualized with the patient. The questions may seem impersonal (e.g. too general and not directly assessing their individual goals, motivations, aspirations), irrelevant (e.g., askin... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
10/05/2023
Locations: University of Texas Health Austin, Austin, Texas
Conditions: PROM
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Sleep Assessment: The Benefits of Identifying Sleep Disturbance Using a Sleep Questionnaire
NCT06074224
Recruiting
The investigators are interested in measuring the influence of addressing sleep in the orthopedic setting. This includes assessing patient experience measures (satisfaction with the visit, perceived empathy, communication effectiveness) as well as greater engagement in their healthcare (patient activation). The investigators will also see what factors might be associated with sleep disturbance and if addressing sleep leads to an intervention such as cognitive behavioral therapy.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
10/05/2023
Locations: University of Texas Health Austin (UTHA), Austin, Texas
Conditions: Sleep Disturbance
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High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation
NCT04973852
Recruiting
The purpose of this study is to see if it's possible to reach high cardiovascular intensity training parameters (exercise at a rate that elevates heart rate to the level recommended for improving strength and endurance) while walking in a wearable robotic exoskeleton. This study will also evaluate if exercising at high intensity will lead to improvement in walking ability. Participants in this study will be asked to attend 5 walking training sessions using Ekso exoskeleton. There will be two add... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: NeuroRecovery Research Center at TIRR Memorial Hermann, Houston, Texas
Conditions: Spinal Cord Injuries
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LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
NCT04759664
Recruiting
The study evaluates the efficacy and safety of two strengths of LUT014 Gel topically applied once a day for 4 weeks, compared to placebo, in metastatic colorectal cancer (mCRC) patients who developed Grade 2 or non-infected Grade 3 EGFRI induced acneiform lesions
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: EGFRI Induced Acneiform Lesions
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A Study of Belantamab Mafodotin in Multiple Myeloma Participants With Normal and Impaired Hepatic Function
NCT04398680
Recruiting
The purpose of this study is to assess the pharmacokinetics (PK), safety, and tolerability of belantamab mafodotin monotherapy in Relapsed/Refractory Multiple Myeloma (RRMM) participants with impaired hepatic function and in matched RRMM participants with normal hepatic function.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: GSK Investigational Site, The Woodlands, Texas
Conditions: Multiple Myeloma
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Extracellular RNA Biomarkers of Myotonic Dystrophy
NCT05020002
Recruiting
Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
10/04/2023
Locations: University of Texas Southwestern, Dallas, Texas
Conditions: Myotonic Dystrophy
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