Texas is currently home to 5037 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of RX108 in Patients With Locally Advanced or Metastatic Solid Tumors
Recruiting
RX108 is a novel, potent, small-molecule inhibitor of Na+/K+-ATPase. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK) and efficacy of RX108 in patients with locally advanced or metastatic solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2022
Locations: University of Texas at MD Anderson Cancer Center, Houston, Texas
Conditions: Locally Advanced Solid Tumors, Metastatic Solid Tumors
Reducing Mental Health in Informal Caregivers
Recruiting
The overarching goal of this project is to evaluate if evidence-based interventions can reduce PDG, burden, and stress in informal caregivers of individuals with dementia
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/11/2022
Locations: Texas Tech University, Lubbock, Texas
Conditions: Mental Health Issue, Grief, Burden, Caregiver
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
Recruiting
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2022
Locations: PRX Research/Dallas Regional Medical Center, Mesquite, Texas
Conditions: Covid19
An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection
Recruiting
The goal of the current study is to evaluate the ability of CGB-400, a proprietary eutectic mixture of GRAS compounds, to clear the toenail fungal growth and improve the appearance of the fungus affected area(s). This is an open-label, single group POC study evaluating the effectiveness of CGB-400 Topical Gel for toenail fungal growth clearing. The study consists of a 12-week period with 5 clinic visits at the following timepoints: Baseline (Day 0), and Weeks 2, 6, and 12 and post-application f... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/05/2022
Locations: John Peter Smith Hospital, Fort Worth, Texas
Conditions: Fungal Infection, Onychomycosis, Tinea Unguium
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD)
Recruiting
This is a comparative effectiveness study of two pragmatic models aiming to introduce palliative care for end stage liver disease patients. The 2 comparators are: Model 1: Consultative Palliative Care (i.e. direct access to Palliative Care provider), Model 2: Trained Hepatologist- led PC intervention (i.e. a hepatologist will receive formal training to deliver Palliative Care services) Primary Outcome: The change in quality of life from baseline to 3 months post enrollment as assessed by FACT-... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/05/2022
Locations: Baylor College of Medicine, Houston, Texas
Conditions: End Stage Liver Disease
Development of Protocols and Methods for Image Processing and Enhancement of Magnetic Resonance Imaging (MRI) Data.
Recruiting
The purpose of the study is to develop new methods for image processing and enhancement of MRI data. Different setting of acquisition parameters used in conventional clinical MRI protocols will be defined, to create "New Protocols". The specific aim of this study is to assess and to improve the performance of our image processing methods, by comparing diagnostic qualities of images obtained by conventional MRI protocols with those obtained by corresponding New Protocols' and processed by our im... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2022
Locations: Houston Medical Imaging, Houston, Texas
Conditions: MRI Image Enhancement
Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)
Recruiting
The purpose of this study is to investigate the use of autologous umbilical cord blood (UCB) mononuclear cells to mitigate hypoxic neurologic injury among infants with high-risk congenital diaphragmatic hernia (CDH).
Gender:
All
Ages:
Between 10 minutes and 7 days
Trial Updated:
03/31/2022
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Congenital Diaphragmatic Hernia
Study to Evaluate Effects of INL1 in Patients With Heart Failure and Reduced Ejection Fraction
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, dose-response trial in patients with chronic stable Heart Failure (HF) and reduced Left Ventricular Ejection Fraction (LVEF) to evaluate the efficacy and safety of three INL1 doses compared with placebo. Patients will be treated for approximately 12 weeks with one of three INL1 doses: 50 mg, 150 mg, 300 mg, or, placebo capsules, taken twice daily (BID).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/28/2022
Locations: East Texas Cardiology, Houston, Texas
Conditions: Heart Failure, Reduced Ejection Fraction
Mitochondrial Capacity Boost in ALS (MICABO-ALS) Trial
Recruiting
The purpose of this research is to investigate the validity of a previous clinical trial named EH301, which showed beneficial effects of anti-oxidant therapies in patients with amyotrophic lateral sclerosis (ALS). If validated by this study, providing over-the-counter anti-oxidants would be a simple, low risk, low-cost approach to significantly slow or stop the progression of ALS, for which currently no effective treatment exists. It is currently thought that oxidative stress is a major cause of... Read More
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
03/25/2022
Locations: VA North Texas Health Care System, Dallas, Texas
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Virtual Reality Pain Study
Recruiting
Investigating pain in hospitalized patients in two groups: virtual reality usage group vs standard of care
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2022
Locations: Baylor Institute for Rehabilitation, Dallas, Texas
Conditions: Hospitalized Patients 18 Years of Age or Older With Pain
The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes
Recruiting
The objective of this study is to collect both active and passive data using a wearable, multi-sensor device (Verily Study Watch) and phone application (Mood App) which aims to capture mental health status, in subjects participating in the RECOVER clinical trial (A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2022
Locations: BioBehavioral Research of Austin, Austin, Texas
Conditions: Treatment Resistant Depression
Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease
Recruiting
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2022
Locations: Prolato Clinical Research Center, Houston, Texas
Conditions: Glomerular Disease, Proteinuria