Texas is currently home to 5044 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Prospective Evaluation and Comparison of Bilateral Synergy Implants and Bilateral PanOptix Implants
Recruiting
The purpose of this study is to evaluate the AcrySof PanOptix Intraocular Lens (IOL) for binocular distance corrected near visual acuity (DCNVA) compared to TECNIS Synergy IOL. Presbyopia correcting diffractive intraocular implants (extended depth of focus, multifocal, and trifocal) provide cataract and refractive surgeons with an effective treatment means for allowing patients to experience increased spectacle independence post-cataract surgery.
Gender:
All
Ages:
22 years and above
Trial Updated:
01/10/2022
Locations: Lehmann Eye Center, Nacogdoches, Texas
Conditions: Cataract
Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
Recruiting
The purpose of the study is to assess vascular function in African Americans, Hispanic and Caucasian Americans to better understand racial differences in cardiovascular health. The investigators will further investigate the affect of Beetroot juice on the vascular function of all participants.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
01/07/2022
Locations: University of Texas at Austin, Austin, Texas
Conditions: Healthy Adults
Impact of CBD-Rich Oil on Aversive Memory Reconsolidation
Recruiting
The purpose of this study is to test whether cannabidiol (CBD) rich hemp extract oil can interfere with the reconsolidation (storage) of pathological fear memory in humans.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
01/03/2022
Locations: University of Texas, Austin, Texas
Conditions: Anxiety and Fear
ERAS® Guidelines Validation of CRS With or Without HIPEC
Recruiting
Enhanced recovery after surgery (ERAS®) pathways have been shown to considerably reduce complications, length of stay and costs after most of surgical procedures by standardised application of best evidence-based perioperative care. Recently an international panel of expert have succeeded to elaborate dedicated recommendations for cytoreductive surgery (CRS) ± hyperthermic intraperitoneal chemotherapy (HIPEC) in a two-part series of guidelines based on expert consensus (Hübner et al., EJSO, 2020... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/22/2021
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Peritoneal Diseases
Proof of Principle Study to Evaluate the Safety, PK, Viral Shedding and Efficacy of Pentarlandir™ UPPTA for Patients With Early COVID-19
Recruiting
This is a clinical trial to evaluate the safety, PK, viral shedding and clinical effects of Pentarlandir™ UPPTA in patients with early COVID-19. Approximately 90 ambulatory subjects with mildly symptomatic early COVID-19, who have been diagnosed with COVID-19 within the prior 4 days will be enrolled.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
12/16/2021
Locations: Elite Medical Research, Dallas, Texas
Conditions: Coronavirus Disease 2019
A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma
Recruiting
This study will be a multicenter, prospective, open label, one-arm study intended to assess the Safety and Efficacy of EscharEx (EX-02) in the treatment of Basal Cell Carcinoma. In patients with one primary superficial or nodular basal cell carcinoma lesion with a diameter of 5-10mm (Histologically confirmed BCC) located on the trunk or upper extremities (not including the hands), with well-defined borders and no previous radiation therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/01/2021
Locations: Center for Clinical Studies, LTD. LLP, Webster, Texas
Conditions: Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
Natural History of COVID-19-Related Atrial Fibrillation
Recruiting
The unCOVer-AF prospective, multicenter registry aims at determining the natural history of atrial fibrillation (AF) via continuous cardiac rhythm monitoring in patients with a first arrhythmic episode during COVID-19 hospitalization.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2021
Locations: Texas Cardiac Arrhythmia Institute, Austin, Texas
Conditions: COVID-19, Atrial Fibrillation New Onset
A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme
Recruiting
The current design provides a window to analyze the impact of the ACT001+Pembrolizumab combination on the tumor microenvironment and disease outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/12/2021
Locations: UT MD Anderson Cancer Center, Dept of Neuro-Oncology, Houston, Texas
Conditions: Recurrent Glioblastoma Multiforme(GBM)
A Phase 1/2, Study of YL-15293 in Subjects With Advanced Solid Tumors With a KRAS G12C Mutation
Recruiting
This is a Phase 1/2, open-label, multicenter study designed to evaluate the maximum tolerated, safety, tolerability and PK of oral YY-15293 in patients with advanced solid tumors with a KRAS G12C mutation, to confirm the recommended phase 2 dose of YY-15293, and to obtain preliminary efficacy information in patients with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/11/2021
Locations: Oncology Consultants, Houston, Texas
Conditions: Advanced Solid Tumor
Sample Collection Study for the CellMax Life Circulating Tumor Cell and Circulating Tumor DNA Platforms for the Early Detection of Colorectal Cancer and Adenomas
Recruiting
The purpose of this study is to collect clinical specimens from subjects with a diagnosis of colorectal cancer/advanced adenoma or undergoing a screening colonoscopy and meeting study eligibility criteria.
Gender:
All
Ages:
Between 45 years and 80 years
Trial Updated:
11/09/2021
Locations: CellMax Site K, Houston, Texas
Conditions: Colorectal Cancer Screening
Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer
Recruiting
Esophageal cancer, which has a low 5-year overall survival rate for all stages (<20%) , is increasing in incidence. Previous studies have shown that the Hedgehog (Hh) and AKT signaling pathways are activated in a significant proportion of esophageal cancers. Itraconazole, a widely used anti-fungal medication, has been shown to inhibit various pathways involved in esophageal cancer tumorigenesis including Hh and AKT. In this phase II clinical trial, the investigators aim to evaluate the effect of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2021
Locations: Dallas VA Medical Center, Dallas, Texas
Conditions: Esophagus Adenocarcinoma, Esophagus Squamous Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma
Micro-hematology Analyzer for Viral/Bacterial Description
Recruiting
The purpose of the study is to evaluate the reliability and accuracy of a newly developed point-of-care analyzer, theCytoTracker, to measure complete blood count (CBC) parameters and discriminate between viral and bacterial infections.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
10/26/2021
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Infection Viral, Infection, Bacterial