Texas is currently home to 5044 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Verticalization Robotic Exoskeleton DoC
Recruiting
Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but this modality has not been thoroughly explored. The primary aim of this study is to compare the influence of verticalization with and without vestibular input on level of consciousness in patients experiencing disorders of consciousness (DoC).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/31/2021
Locations: TIRR Memorial Hermann, Houston, Texas
Conditions: Brain Injuries, Disorder of Consciousness
Genetic Mechanism of Conserved Ancestral Haplotype in SCA10
Recruiting
Spinocerebellar ataxia type 10 (SCA10) is a hereditary ataxia whose ancestral mutation occurred in East Asia. The mutation is likely to have migrated during peopling of American continents from East Asia. We found a specific rare DNA variation associated with SCA10. We test whether this variation played a key role in the birth and subsequent spreading of SCA10 mutation.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/30/2021
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Spinocerebellar Ataxia Type 10
The Impact of Social Phone Calls With Isolated Older Adults Receiving Protective Services for Abuse, Neglect and/or Exploitation
Recruiting
The purpose of this study is to see the the impact of social visits, through weekly phones calls, on quality of life outcomes of depression, anxiety, loneliness, isolation and self-rated health for older adults visited by Adult Protective Services (APS) for abuse, neglect and/or exploitation (ANE) and to also to determine the benefit of these conversations on the medical student's perspective of aging and ANE.
Gender:
All
Ages:
65 years and above
Trial Updated:
08/24/2021
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Senior Abuse
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: B-cell Acute Lymphoblastic Leukemia
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery
Recruiting
Cardiopulmonary bypass and arrest of the heart during cardiac surgery are necessary to allow the surgeon to perform heart operations. However, these processes can cause injury to the heart which may worsen post-operative outcomes. In fact, the effects of these injuries may continue after surgery, and lead to a long-term decrease in heart function. Neonates and young infants are at particular risk for this occurrence. While much research has been done in adults looking for medicines that might p... Read More
Gender:
All
Ages:
1 year and below
Trial Updated:
08/02/2021
Locations: Dell Children's Medical Center of Central Texas, Austin, Texas
Conditions: Heart Defects, Congenital
Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair
Recruiting
A multicenter, single-dose study in children 12 to <17 years of age, 6 to <12 years of age, and 2 to <6 years of age who are scheduled for elective open inguinal hernia repair. Enrollment in this study will start with the oldest age group (12 to <17 years) and will continue in a stepwise fashion until appropriate doses are established for all 3 pediatric age groups (12 to <17 years, 6 to <12 years, 2 to <6 years).
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
07/23/2021
Locations: Driscoll Children's Hospital, Corpus Christi, Texas
Conditions: Inguinal Hernia, Postoperative Pain
Breast Mesh Used in Two-staged Breast Reconstruction
Recruiting
This is the first prospective randomized and controlled study on the efficacy and safety of TiLOOP® Bra mesh in patients with expander-implant breast reconstruction. The investigators hypothesize that incoporating TiLOOP Bra mesh with tissue expanders will reduce the rates of capsular contraction, improve the efficiency of expansion and provide better aesthetic result.
Gender:
Female
Ages:
Between 18 years and 70 years
Trial Updated:
07/19/2021
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Breast Cancer, Radiation, Breast Reconstruction, Synthetic Mesh
Prospective US Radiofrequency SUI Trial
Recruiting
PURSUIT: Prospective US Radiofrequency SUI Trial (VI-17-06) is a prospective, randomized, sham controlled, double blind study in premenopausal women with stress urinary incontinence. The study will be conducted in 390 subjects, randomized 2:1 with active or sham treatment. Study duration is 12 months post treatment. The primary objective is to evaluate the efficacy of the Viveve treatment, SUI protocol, in improving mild to moderate stress urinary incontinence (SUI), assessed using the 1-hour Pa... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/19/2021
Locations: Advances In Health Research, Houston, Texas
Conditions: Urinary Incontinence, Stress
Retention of Whole-body Training Effects on Ambulatory Function in Children With Cerebral Palsy
Recruiting
This study will evaluate the retention effects of a four-week whole-body vibration training intervention in children with Cerebral Palsy. The primary outcomes for this study are gait function, including Timed Up and Go and the two-minute walk test. Secondary outcomes of this study include lower extremity gait function, coordination, and gait variability. For this study, a total of 10 children with Cerebral Palsy (CP) will be recruited with 5 being randomly placed into an experimental group and 5... Read More
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
07/02/2021
Locations: The University of Texas at El Paso, El Paso, Texas
Conditions: CP, Gait Disorders, Neurologic, Locomotion Disorder, Neurologic
Foundational Ingredients of Robotic Gait Training for People With Spinal Cord Injury During Inpatient Therapy
Recruiting
The FIRST project compares the dose of robotic gait training (RGT) with usual care gait training for patients with spinal cord injury (SCI) undergoing rehabilitation at Baylor Scott & White Institute for Rehabilitation (BSWIR).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
06/30/2021
Locations: Baylor Scott & White Institute for Rehabilitation, Dallas, Texas
Conditions: Spinal Cord Injuries
Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: TMC Life Research, Houston, Texas
Conditions: Female Sexual Arousal Disorder
Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery
Recruiting
The purpose of this study is to find out what effects (good and bad) that the study medicine called "liposomal bupivacaine" has on subjects that are undergoing a sternotomy. Liposomal bupivacaine solution, is a drug that the doctor will inject before they make the cut through patient's breastbone (sternotomy). Normally pain medicine like this is given right before the surgeon closes up the patient's breastbone, at the end of the surgery. For this study, they want to see if giving the medicine be... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2021
Locations: Baylor Scott & White Heart Hospital - Plano, Plano, Texas
Conditions: Cardiovascular Surgery, Pain, Postoperative, Block