Texas is currently home to 5071 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy. (LIMBER-213)
Recruiting
This is a 2-part study. In Part 1, participants will be dosed at 2 different dose levels in order to select the RP2D for Part 2 of the study.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2021
Locations: Renovatio Clinical Consultants Llc, Spring, Texas
Conditions: Myelofibrosis, Polycythemia Vera, Thrombocythemia
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: Renovatio Clinical, Houston, Texas
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery
Recruiting
The two main objectives of this study are to demonstrate safety and effectiveness of implanting the PanOptix Trifocal IOL in patients who have had previous myopic Lasik. The primary objectives to demonstrate clinical safety will be the quality of vision questionnaire (QUVID) which will demonstrate the patient's perception of halos, glares, and starbursts before and after the implantation of the trifocal IOL. The primary objective to demonstrate clinical effectiveness will be done by measuring v... Read More
Gender:
All
Ages:
22 years and above
Trial Updated:
03/15/2021
Locations: Parkhurst NuVision, San Antonio, Texas
Conditions: Cataract, Refractive Errors
Pullback Pressure Gradient (PPG) Global Registry
Recruiting
The purpose of this study is to determine the predictive capacity of the Pullback Pressure Gradient (PPG) index for post-PCI FFR and to determine the impact of the PPG index on clinical decision making about revascularization and on clinical outcomes.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/04/2021
Locations: Memorial Hermann Texas Medical Center, Texas City, Texas
Conditions: Chronic Coronary Insufficiency, Non ST Elevation Myocardial Infarction
Veteran Affairs Osteoarthritis Knee Study
Recruiting
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in patients with knee osteoarthritis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/04/2021
Locations: Veteran Affairs North Texas Healthcare System, Dallas, Texas
Conditions: Knee Osteoarthritis
Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
Recruiting
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2021
Locations: The University of Texas Medical Branch at Galveston, Galveston, Texas
Conditions: Ankle Arthritis, Foot Arthritis
Reclaim™ Deep Brain Stimulation (DBS) Therapy for Obsessive-Compulsive Disorder (OCD)
Recruiting
There are two primary approaches to the treatment of OCD, pharmacotherapy and cognitive behavior therapy (CBT). Lack of therapeutic success with one approach leads to trials of the alternative approach or a combination of the two. A rarely used third therapy approach, appropriate for only the most severely afflicted and treatment resistant patients, is neurosurgical ablation of certain brain regions involved in mood and anxiety. The neurosurgical ablation procedures are irreversible in nature, a... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/12/2021
Locations: UT Health Science Center at Houston, Houston, Texas
Conditions: Obsessive-Compulsive Disorder (OCD)
Study to Assess the Food Effect of K-877 in Healthy Adult Volunteers
Recruiting
Study is to assess the effects of food on the Pharmacokinetics(PK) of single-dose administration of K-877 in healthy adult volunteers.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
02/02/2021
Locations: PPD Development, LP, Austin, Texas
Conditions: Healthy
Immune Response Following COVID-19 Vaccination
Recruiting
Few trials have reported the safety and efficacy of the COVID-19 vaccines. However, these trials were mostly focused on post-vaccination adverse events and short-term antibody detection with none monitoring the presence of immunoglobulin G (IgG) in blood at long-term follow-up after the vaccination. This study aims to evaluate the immune response in post-vaccinated individuals across a follow-up period of one year.
Gender:
All
Ages:
Between 16 years and 85 years
Trial Updated:
02/02/2021
Locations: Texas Cardiac arrhythmia Institute, St. David's Hospital, Austin, Texas
Conditions: IgM and IgG in Blood
Safety and Efficacy of Endoscopic Assisted Push Gastrostomy Using Gastrostomy Technique
Recruiting
Most pediatric gastroenterologists use an endoscopic pull technique to place gastrostomy tubes. We assessed an endoscopic gastropexy technique for gastrostomy tube placement that allows immediate placement of a low profile gastrostomy tube or gastro-jejunostomy tube. The procedure involves endoscopy with the placement of three T-fasteners that are placed through the skin into the stomach, placating and securing the stomach to the abdominal wall. This attachment process promotes formation of a st... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
01/26/2021
Locations: The Children's Hospital of San Antonio, San Antonio, Texas
Conditions: Gastrostomy, Gastrostomy Complications, Gastrostomy Tube Site Complication, Pain, Postoperative
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Amarillo, Texas
Conditions: Ulcerative Colitis
Comparison Of Radiation Exposure To Patients During Endoscopic Retrograde Cholangiopancreatography (ERCP) Performed By Endoscopists Trained In Judicious Use Of Fluoroscopy With Those Without Formal Training
Recruiting
Purpose: To compare the radiation exposure in patients during Endoscopic retrograde cholangiopancreatography (ERCP) done by Endoscopists formally trained in judicious use of fluoroscopy versus ERCPs done by Endoscopists without such formal training. Research design: This is an observational study to compare radiation exposure in patients during ERCPs based on formal training. Procedures to be used: None Risks and potential benefits There are no risks associated with this study as it is a retro... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
01/11/2021
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Pancreatic Cancer