Texas is currently home to 5040 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
NCT02803957
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
All
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: Baylor - Plano, Plano, Texas
Conditions: Mitral Valve Insufficiency
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Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
NCT03050762
Recruiting
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
Gender:
All
Ages:
All
Trial Updated:
09/13/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Endocrine Disease
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Sugammadex vs. Placebo to Prevent Residual Neuromuscular Block in the Post---Anesthesia Care Unit
NCT02822001
Recruiting
The Primary objective of this study is to determine whether patients who receive sugammadex immediately after tracheal extubation will exhibit a decrease in the incidence of postoperative residual paralysis and an associated decrease in the incidence of postoperative respiratory depression (which can precede critical respiratory events, CRE). The Secondary objectives are to: a) determine whether patients receiving sugammadex will have a normal TOF ratio (>0.90) indicative of full neuromuscular... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2019
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Neuromuscular Blockade, Respiratory Insufficiency
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Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients
NCT03048266
Recruiting
Objectives: The aim of the present study is to assess the significance of metabolomics and genetics in diagnosing and survival evaluation for pNET in the periodic follow-up of MEN1 patients. Aim 1: To evaluate the relationship of serum global metabolic profiles with subsequent development of aggressive PNET and evaluate patients survival in a nested case-control study of MEN1 patients who have developed aggressive PNETs (cases) and MEN1 patients who have developed non-aggressive PNETs (control... Read More
Gender:
All
Ages:
All
Trial Updated:
05/21/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Multiple Endocrine Neoplasia
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Prospective Study of Colon Serrated Polyps
NCT02332785
Recruiting
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions. The findings will help us define the natural history of colon serrated lesions, develop techniques for endoscopic management of patients with serrated lesions, and identity areas for improvement. The data will be used for continuing quality improvement and presenting our outcomes at academic meeting... Read More
Gender:
All
Ages:
All
Trial Updated:
05/13/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Colon Polyps
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Prospective Study of Colonoscopic Resection of Large Polyps and Flat Lesions
NCT02332772
Recruiting
With this study, the investigators plan to review the performance of colonoscopic resection of large (> 1 cm) and flat lesions in the colon. The findings will help us define the role of colonoscopic resection of colon polyps and flat lesions and identity areas for improvement. The data will be used for continuing quality improvement and presenting our outcomes at academic meetings and publishing our results in peer reviewed journals.
Gender:
All
Ages:
All
Trial Updated:
05/10/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Colon Polyps
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The Collection and Storage of Umbilical Cord Blood for Transplantation
NCT01728545
Recruiting
The goal of this study is to collect blood samples from the umbilical cords of newborn babies, as soon as they are delivered, and to place these samples in the MD Anderson Cord Blood Bank. Your sample may be included in the National Cord Blood Inventory (NCBI) which is part of the CW Bill Young Cell Transplantation Program. The NCBI is a federally-supported program to assist in the collection of cord blood. Cord blood will be made available to patients through The National Marrow Donor Program (... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/10/2019
Locations: MD Anderson Cord Blood Bank Collection Sites, Houston, Texas
Conditions: Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Hematopoietic Stem Cell Transplantation
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Use of the OMNI® Surgical System in Combination With Cataract Extraction in Open Angle Glaucoma
NCT03861169
Recruiting
This study will prospectively assess the clinical effect of ab-interno transluminal viscoelastic delivery and trabeculotomy performed using the OMNI Surgical System in combination with Cataract Extraction on intraocular pressure (IOP) and the use of IOP-lowering medications in patients with mild-moderate open angle glaucoma (OAG).
Gender:
All
Ages:
22 years and above
Trial Updated:
02/28/2019
Locations: El Paso Eye Surgeons, El Paso, Texas
Conditions: Open Angle Glaucoma
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SOLEMN Study - Synergy Optical Coherence Tomography in Left Main PCI
NCT03474432
Recruiting
BACKGROUD: Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main coronary artery stenosis. Protected LM PCI is considered standard of care in most centers. OCT allows for precise determination of stent placement, stent expansion and apposition. The pattern of vessel healing can be very precisely studied if immediate post-stent implantation OCT/IVUS data is compared to the 6-month post-PCI interval. While OCT cannot be optimally used for ostial lesion ima... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/14/2019
Locations: Dallas VA Medical Center, Dallas, Texas
Conditions: Percutaneous Coronary Intervention, Optical Coherence Tomography, In-stent Coronary Artery Restenosis
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The Diabetic Foot Ulcer Registry
NCT02813161
Recruiting
This is an observational, longitudinal real world registry of diabetic foot ulcers created from electronic health record data obtained in the course of clinical care. Data from certified electronic health records transmit data as part of the requirement to share data with a specialty registry under Objective 10 of Meaningful Use of an EHR.
Gender:
All
Ages:
All
Trial Updated:
04/30/2018
Locations: CHI St. Luke's The Woodlands, The Woodlands, Texas
Conditions: Diabetic Foot Ulcer Outcome, Quality of Patient Care
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A Real World, Observational Registry of Chronic Wounds and Ulcers
NCT02280733
Recruiting
More than 100 hospital based outpatient wound centers in the USA and Puerto Rico agree to transmit structured data on all patients followed with chronic wounds and ulcers (e.g. diabetic foot ulcers, venous ulcers, pressure ulcers, arterial ulcers, surgical wounds, and traumatic wounds). Data are collected at point of care including adherence to wound care quality measures developed by the USWR as a Qualified Clinical Data Registry (QCDR).
Gender:
All
Ages:
All
Trial Updated:
04/30/2018
Locations: US Wound Registry, The Woodlands, Texas
Conditions: Diabetic Foot, Varicose Ulcer, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Wounds and Injuries, Pyoderma, Peripheral Arterial Disease, Diabetic Neuropathies, Lymphedema, Venous Insufficiency, Diabetes Complications, Amputation Stump
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HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
NCT01913106
Recruiting
The purpose of this study is to conduct a Phase I - II clinical trial to extend preclinical studies involving in situ HSV-tk + Valacyclovir gene therapy in combination with brachytherapy for recurrent prostate cancer. This will provide a novel therapeutic approach to prostate cancer and hopefully impact on the development of metastatic disease and the control of preexisting metastasis.
Gender:
Male
Ages:
All
Trial Updated:
06/29/2016
Locations: Houston Methodist, Houston, Texas
Conditions: Prostatic Neoplasms
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