There are currently 135 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
NCT05081596
Recruiting
The purpose of the study is to examine the effect of Problem Adaptation Therapy for Pain (PATH-Pain) on cognitive functioning, depression and pain-related disability in 100 older adults with cognitive impairment, chronic pain, and depression. The study will test if PATH-Pain has better cognitive, affective, and functional outcomes than Attention Control Usual Care.
Gender:
All
Ages:
60 years and above
Trial Updated:
06/11/2024
Locations: Weill Cornell Medicine, White Plains, New York
Conditions: Depression, Pain, Cognitive Impairment
Register for Updates
Post-stroke Pain taVNS
NCT06456385
Recruiting
The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain. Investigators will recruit up to 20 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/07/2024
Locations: Medical University of South Carolina Institute of Psychiatry, Charleston, South Carolina
Conditions: Stroke, Pain
Register for Updates
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
NCT06214923
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
06/05/2024
Locations: Luana Colloca, Baltimore, Maryland +1 locations
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Register for Updates
Relaxing Environment to Lower Anxiety During Onabotulinum Toxin Chemodenervation of the Bladder
NCT06319898
Recruiting
Chemodenervation of the bladder with onabotulinum toxin A is an effective treatment option for patients with refractory urgency urinary incontinence (UUI). It is often performed as an office-based procedure under local anesthesia. Alternatively, it can be performed in the operating room under general anesthesia. The ability to receive intra-detrusor chemodenervation in the office allows patients to avoid the risks associated with general anesthesia and is significantly more cost effective. The p... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Anxiety, Pain, Burnout, Professional
Register for Updates
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
NCT04851301
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
05/22/2024
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Register for Updates
Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment
NCT06426238
Recruiting
Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels. Studies have assessed the difference in pain levels between clear aligners and fixed appliances using subjective pain scales. No study has utilized PPT to evaluate the difference in pain between aligners and fixed braces at different time points. This study will aim to compare the self- reported and experimental pain pe... Read More
Gender:
All
Ages:
14 years and above
Trial Updated:
05/17/2024
Locations: Midwestern University, Downers Grove, Illinois
Conditions: Pain
Register for Updates
Cannabis Effects as a Function of Sex (CanSex)
NCT04385082
Recruiting
The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
05/15/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Abuse, Drug
Register for Updates
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
NCT06326983
Recruiting
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondar... Read More
Gender:
All
Ages:
Between 3 years and 17 years
Trial Updated:
05/13/2024
Locations: Boston Children's Hospital, Waltham, Massachusetts
Conditions: Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction, Anesthesia, Pain
Register for Updates
Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
Register for Updates
Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI
NCT05492188
Recruiting
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and training phases followed by 1 month and 3 month follow-up visits).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/02/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Spinal Cord Injuries, Neuropathic Pain, Neurological Injury, Pain
Register for Updates
Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA
NCT05468398
Recruiting
The study team aims to investigate whether implementing virtual reality therapy (VRT) during Genicular nerve radiofrequency ablation (GNRFA) procedure will provide better alleviation of procedural pain and augmented satisfaction for patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: UC Irvine Gottschalk Medical Plaza, Irvine, California
Conditions: Pain, Patient Satisfaction
Register for Updates
The Role of Virtual Reality During Regional Anesthesia
NCT04163809
Recruiting
In this study, we will analyze the role of virtual reality in acute pain and anxiety management for regional anesthesia in pre-operative patients at Cedars-Sinai Medical Center.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/12/2024
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Anxiety, Pain
Register for Updates