There are currently 127 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Applying Num Vapocoolant Spray to Cervix Before Paracervical Block to Decrease Pain During Gynecology Procedures
NCT06227052
Recruiting
The purpose of this study is to assess if Num vapocoolant spray decreases pain associated with paracervical block in gynecology procedures.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: Queens Medical Center POB1 Clinic 1004, Honolulu, Hawaii
Conditions: Pain With Paracervical Block, Pain With Gynecology Procedure, Pain
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Measuring Analgesic Interventions
NCT03794362
Recruiting
It is generally recognized that pain assessment and management especially in newborns, children and other nonverbal populations is an unmet need. According to the American Medical Association, "the pediatric population is at risk of inadequate pain management, with age-related factors affecting pain management in children. Children are often given minimal or no analgesia for procedures that would routinely be treated aggressively in adults. Although much is now known about pain management in chi... Read More
Gender:
ALL
Ages:
Between 7 years and 21 years
Trial Updated:
07/03/2024
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Pain
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Reliability of Pupil Response to Acute Pain
NCT02628314
Recruiting
The purpose of this research study is to test whether researchers can reliably measure the response pupils have when an acute painful stimulus is experienced. Changes in the size of the pupil of the eye can be an indicator of brain activity in a region of the brain that is important for feeling pain.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/27/2024
Locations: Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Conditions: Pain, Osteoarthritis
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Neural Correlates of Hypoalgesia Driven by Observation
NCT03897998
Recruiting
Placebo effects held an ambivalent place in health care for at least two centuries. On the one hand, placebos are traditionally used as controls in clinical trials to correct for biases and the placebo response is viewed as an effect to be factored out in order to isolate and accurately measure the effects of the treatment. On the other hand, there is scientific evidence that placebo effects represent fascinating psychoneurobiological events involving the contribution of distinct central nervous... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/26/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo
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Impact of Bluetooth Haptics Device Distraction on Mechanical Pain Thresholds Induced by PinPrick Stimulators
NCT06271642
Recruiting
This is a prospective, crossover study of healthy participants evaluating the mechanical pain threshold for weighted pinprick stimuli.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
06/22/2024
Locations: Lucile Parkard Children's Hospital, Stanford, California
Conditions: Pain, Anxiety
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More Sleep: Pain Response to Longer Sleep
NCT05816434
Recruiting
This study is being done to find out whether extending sleep for at least an hour per night, seven days a week, predicts a higher tolerance and a higher threshold for pain. This is a 21-day study. Participants will be asked to wear sleep- and heart- monitoring watches. Pressure pain and cold pain will be measured at study visits.
Gender:
ALL
Ages:
Between 18 years and 24 years
Trial Updated:
06/19/2024
Locations: Pennsylvania State University, University Park, Pennsylvania
Conditions: Sleep, Pain
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A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
NCT05081596
Recruiting
The purpose of the study is to examine the effect of Problem Adaptation Therapy for Pain (PATH-Pain) on cognitive functioning, depression and pain-related disability in 100 older adults with cognitive impairment, chronic pain, and depression. The study will test if PATH-Pain has better cognitive, affective, and functional outcomes than Attention Control Usual Care.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/11/2024
Locations: Weill Cornell Medicine, White Plains, New York
Conditions: Depression, Pain, Cognitive Impairment
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Post-stroke Pain taVNS
NCT06456385
Recruiting
The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain. Investigators will recruit up to 20 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/07/2024
Locations: Medical University of South Carolina Institute of Psychiatry, Charleston, South Carolina
Conditions: Stroke, Pain
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Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
NCT06214923
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
06/05/2024
Locations: Luana Colloca, Baltimore, Maryland +1 locations
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
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Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
NCT04851301
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
05/22/2024
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
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Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment
NCT06426238
Recruiting
Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels. Studies have assessed the difference in pain levels between clear aligners and fixed appliances using subjective pain scales. No study has utilized PPT to evaluate the difference in pain between aligners and fixed braces at different time points. This study will aim to compare the self- reported and experimental pain pe... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
05/17/2024
Locations: Midwestern University, Downers Grove, Illinois
Conditions: Pain
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Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
NCT06326983
Recruiting
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondar... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
05/13/2024
Locations: Boston Children's Hospital, Waltham, Massachusetts
Conditions: Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction, Anesthesia, Pain
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