There are currently 132 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Pain participants are California, Ohio, Florida and Illinois.
Neural and Psychological Mechanisms of Pain Perception
NCT02446262
Recruiting
Background: - Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, not just pain. Researchers want to understand how different factors influence pain. They want to test what happens when people expect different levels of pain and receive treatments that can modify pain. They want to see if these factors influence decisions about pain and how the body responds to it. They also want to compare pain with resp... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
05/23/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Pain, Normal Physiology, Healthy Volunteers
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Chronic Pain Diagnosis and Treatment in Torture Survivors
NCT04629963
Recruiting
The goal Aim 1 of this investigation is to characterize the diagnosis of chronic pain in torture survivors. The investigators hypothesize that using a validated pain screen to supplement the existing United Nations Istanbul Protocol can improve the ability to detect pain from 15% to 90% in this study population. Investigators will test this hypothesis by conducting a prospective, blind comparison to gold standard study. The goal of Aim 2 is to evaluate the acceptability of somatic pain treatment... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: Bellevue/New York University Program for Survivors of Torture, New York, New York +3 locations
Conditions: Pain, Pain, Chronic
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Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
NCT04851301
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
05/22/2024
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
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Relaxing Environment to Lower Anxiety During Onabotulinum Toxin Chemodenervation of the Bladder
NCT06319898
Recruiting
Chemodenervation of the bladder with onabotulinum toxin A is an effective treatment option for patients with refractory urgency urinary incontinence (UUI). It is often performed as an office-based procedure under local anesthesia. Alternatively, it can be performed in the operating room under general anesthesia. The ability to receive intra-detrusor chemodenervation in the office allows patients to avoid the risks associated with general anesthesia and is significantly more cost effective. The p... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/22/2024
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: Anxiety, Pain, Burnout, Professional
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The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial
NCT06075797
Recruiting
The goal of this pilot randomized controlled trial is to test the feasibility of running a full scale randomized controlled trial that compares the effect of the PQ-ResPOND intervention versus usual care to improve recurrent pain in children, adolescents, and young adults with severe neurologic impairment. The main questions it aims to answer are: Is the study feasible and acceptable for participants? Does PQ-ResPOND have a potential to be effective? Participants will: answer surveys (their p... Read More
Gender:
All
Ages:
1 year and above
Trial Updated:
05/20/2024
Locations: University of Alabama, Birmingham, Birmingham, Alabama +3 locations
Conditions: Cerebral Palsy Infantile, Disabilities Multiple, Pain
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Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment
NCT06426238
Recruiting
Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels. Studies have assessed the difference in pain levels between clear aligners and fixed appliances using subjective pain scales. No study has utilized PPT to evaluate the difference in pain between aligners and fixed braces at different time points. This study will aim to compare the self- reported and experimental pain pe... Read More
Gender:
All
Ages:
14 years and above
Trial Updated:
05/17/2024
Locations: Midwestern University, Downers Grove, Illinois
Conditions: Pain
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Decreasing Long-term Opioid Use in Cancer Survivors
NCT05067556
Recruiting
This is a feasibility pilot trial assessing a behavioral intervention for chronic pain among disease-free cancer survivors to decrease long-term opioid dependence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Pain, Chronic Pain, Cancer Pain, Survivorship
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A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain
NCT06379893
Recruiting
The purpose of this study is to investigate how topical diclofenac use can improve functional mobility and physical activity primarily, as well as other quality-of-life (QoL) parameters such as sleep, mood, and engagement in daily activities in participants with knee OA.
Gender:
All
Ages:
Between 40 years and 85 years
Trial Updated:
05/15/2024
Locations: Tandem Clinical Research, Marrero, Louisiana +7 locations
Conditions: Pain
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Cannabis Effects as a Function of Sex (CanSex)
NCT04385082
Recruiting
The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
05/15/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Abuse, Drug
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Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids
NCT04928157
Recruiting
Patients with chronic pain who use opioids appear to be at increased risk for breathing issues during sleep, termed sleep disordered breathing (SDB). Treatment of SDB often consists of use of a device during sleep that provides continuous positive airway pressure (CPAP) via a mask interface. The goal of this study is to determine whether patients with chronic pain who use opioids and have SDB might benefit from the use of CPAP in terms of sleep quality, pain, quality of life, and other measures.... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: University of California San Diego, San Diego, California
Conditions: Sleep Disorder; Breathing-Related, Pain, Sleep Apnea, Obstructive Sleep Apnea, Sleep, Sleep Disorder, Chronic Pain, Opioid Use
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Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
NCT06326983
Recruiting
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham. The overall aim is to evaluate the efficacy of an opioid anesthetic plan (morphine, ketorolac, and acetaminophen versus an opioid sparing anesthetic plan (dexmedetomidine, ketorolac and acetaminophen) for perioperative analgesia and recovery time in patients undergoing tonsillectomies and tonsillotomies at Boston Children's Hospital Waltham. Secondar... Read More
Gender:
All
Ages:
Between 3 years and 17 years
Trial Updated:
05/13/2024
Locations: Boston Children's Hospital, Waltham, Massachusetts
Conditions: Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction, Anesthesia, Pain
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Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
NCT04895306
Recruiting
The aim of this trial is to evaluate whether testosterone replacement results in greater improvement in pain perception, pain tolerance, sexual function, physical function and quality of life when compared with placebo in women with chronic back pain treated with opioids who have low testosterone.
Gender:
Female
Ages:
60 years and above
Trial Updated:
05/13/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Pain, Opioid Use, Androgen Deficiency
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