There are currently 133 active clinical trials seeking participants for Pain research studies. The states with the highest number of trials for Autism participants are California, Ohio, Florida and Illinois.
The Warmth, Anticipation, Sensation, Aversion, and Body-part Imaging Study
NCT04653064
Recruiting
This functional magnetic-resonance imaging study of the brain will feature a within-subject crossover design to investigate the effects of a placebo cream on painful thermal stimulation rendered upon eight body sites. The investigators aim to 1.) improve the understanding of how the brain represents thermal pain responses somatotopically (i.e., across different body-sites) 2.) to test these brain representations with and without the presence of a pain-targeted placebo intervention, and 3.) to ex... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Dartmouth College, Hanover, New Hampshire
Conditions: Pain
Register for Updates
Clinical and Scientific Assessment of Pain and Painful Disorders
NCT02707029
Recruiting
Background: Researchers want to better understand pain by studying people with and without different kinds of pain. To do this, researchers will expose people to pleasant and unpleasant sensations. They will ask them questions about their pain. Researchers also want to see if these people are eligible for other research studies at the National Center for Complementary and Integrative Health. Objectives: To study the experience of pain. Also to find people eligible to join other NIH studies.... Read More
Gender:
All
Ages:
Between 12 years and 120 years
Trial Updated:
03/05/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Pain
Register for Updates
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Bunionectomy
NCT06215820
Recruiting
MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after bunionectomy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Investigator site 114, Sheffield, Alabama +14 locations
Conditions: Acute Pain, Post Operative Pain, Pain
Register for Updates
Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy
NCT06215859
Recruiting
MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after herniorrhaphy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Investigator site 210, Sheffield, Alabama +12 locations
Conditions: Acute Pain, Post Operative Pain, Pain
Register for Updates
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment
NCT03258580
Recruiting
Background: People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective: To study if social and cultural factors lead to differences in pain experience and how pain is interpreted by other individuals. Eligibility: Healthy adults ages 18-60 Design: Participants will h... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
03/01/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology, Healthy Volunteers, Pain
Register for Updates
Association Between Body Composition and Pain in Spinal Cord Injury
NCT05459207
Recruiting
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/29/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Pain, Inflammatory Response
Register for Updates
Reduced Opioid Prescription After Laparoscopic Hysterectomy
NCT05548582
Recruiting
Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
Register for Updates
Chronic Pain in Rheumatoid Arthritis
NCT05038553
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of Colorado, Denver, Colorado +4 locations
Conditions: Arthritis, Rheumatoid, Pain
Register for Updates
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
NCT05761574
Recruiting
The purpose of this study is to evaluate how well a fixed combination of acetaminophen/naproxen sodium relieves postoperative dental pain compared with acetaminophen, naproxen sodium and placebo.
Gender:
All
Ages:
Between 16 years and 50 years
Trial Updated:
02/27/2024
Locations: JBR Clinical Research LLC, Salt Lake City, Utah
Conditions: Pain
Register for Updates
Patient-Empowered Mobile Technology in Hospitalized Patients (TRU-PAIN)
NCT02895841
Recruiting
The purpose of this study is to learn more about the ways in which mobile technology can be integrated into inpatient care to help better track pain levels using mobile technology of patients with sickle cell disease, oncology patients, and bone marrow transplant patients. The study will assess whether or not daily mobile monitoring with wearable accelerometers (devices that detect movement as well as heart-rate) to monitor and manage medical treatments can have a lasting positive impact on outc... Read More
Gender:
All
Ages:
Between 8 years and 80 years
Trial Updated:
02/26/2024
Locations: Duke University, Durham, North Carolina
Conditions: Pain
Register for Updates
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
NCT06274008
Recruiting
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR) increase opioid exposure in young athletes. The purpose of the current study is to determine if extended-release Bupivacaine Liposome Injectable Suspension (Exparel) is effective in decreasing at home narcotic consumption compared to standard Bupivacaine Adductor Canal Block f... Read More
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
02/21/2024
Locations: CHOC Children's Hospital, Orange, California
Conditions: ACL Tear, Opioid Misuse, Pain, Anxiety
Register for Updates
Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction
NCT06241742
Recruiting
The goal of this clinical trial is to test the ability of HT-6184 to decrease inflammation and pain in patients after third molar removal. The main question it aims to answer are: Does HT-6184 decrease inflammation in patients after third molar removal? Does HT-6184 decrease pain in patients after third molar removal? Participants will be asked to do the following during the clinical trial: Take a single oral dose of HT-6184 or placebo Allow a oral surgeon remove their third molar teeth Bloo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: CenExel JBR, Murray, Utah
Conditions: Pain
Register for Updates